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Tracking the pose of instruments is a central problem in image-guided surgery. For microscopic scenarios, optical coherence tomography (OCT) is increasingly used as an imaging modality. OCT is suitable for accurate pose estimation due to…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Nils Gessert , Matthias Schlüter , Alexander Schlaefer

Cellular electron cryo-tomography enables the 3D visualization of cellular organization in the near-native state and at submolecular resolution. However, the contents of cellular tomograms are often complex, making it difficult to…

Quantitative Methods · Quantitative Biology 2017-12-29 Xiangrui Zeng , Miguel Ricardo Leung , Tzviya Zeev-Ben-Mordehai , Min Xu

Albeit the recent progress in single image 3D human pose estimation due to the convolutional neural network, it is still challenging to handle real scenarios such as highly occluded scenes. In this paper, we propose to address the problem…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Xiang Guo , Yuchao Dai

Learning and predicting the pose parameters of a 3D hand model given an image, such as locations of hand joints, is challenging due to large viewpoint changes and articulations, and severe self-occlusions exhibited particularly in…

Computer Vision and Pattern Recognition · Computer Science 2018-05-23 Qi Ye , Tae-Kyun Kim

Classifying structural variability in noisy projections of biological macromolecules is a central problem in Cryo-EM. In this work, we build on a previous method for estimating the covariance matrix of the three-dimensional structure…

Computer Vision and Pattern Recognition · Computer Science 2015-12-08 Joakim Andén , Eugene Katsevich , Amit Singer

Cryo-electron microscopy (cryo-EM) has achieved near-atomic level resolution of biomolecules by reconstructing 2D micrographs. However, the resolution and accuracy of the reconstructed particles are significantly reduced due to the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-03 Jing Zhang , Tengfei Zhao , ShiYu Hu , Xin Zhao

In the tasks of image aesthetic quality evaluation, it is difficult to reach both the high score area and low score area due to the normal distribution of aesthetic datasets. To reduce the error in labeling and solve the problem of normal…

Computer Vision and Pattern Recognition · Computer Science 2022-01-11 Xin Jin , Hao Lou , Huang Heng , Xiaodong Li , Shuai Cui , Xiaokun Zhang , Xiqiao Li

Multiple approaches to use deep learning for image restoration have recently been proposed. Training such approaches requires well registered pairs of high and low quality images. While this is easily achievable for many imaging modalities,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Tim-Oliver Buchholz , Mareike Jordan , Gaia Pigino , Florian Jug

We introduce DiffFit, a differentiable algorithm for fitting protein atomistic structures into an experimental reconstructed Cryo-Electron Microscopy (cryo-EM) volume map. In structural biology, this process is necessary to…

Quantitative Methods · Quantitative Biology 2025-01-09 Deng Luo , Zainab Alsuwaykit , Dawar Khan , Ondřej Strnad , Tobias Isenberg , Ivan Viola

Single particle, cryogenic electron microscopy (cryo-EM) experiments now routinely produce high-resolution data for large proteins and their complexes. Building an atomic model into a cryo-EM density map is challenging, particularly when no…

Biomolecules · Quantitative Biology 2020-09-04 Po-Nan Li , Saulo H. P. de Oliveira , Soichi Wakatsuki , Henry van den Bedem

Learned image reconstruction techniques using deep neural networks have recently gained popularity, and have delivered promising empirical results. However, most approaches focus on one single recovery for each observation, and thus neglect…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Chen Zhang , Riccardo Barbano , Bangti Jin

Most recent approaches to monocular 3D pose estimation rely on Deep Learning. They either train a Convolutional Neural Network to directly regress from image to 3D pose, which ignores the dependencies between human joints, or model these…

Computer Vision and Pattern Recognition · Computer Science 2016-05-18 Bugra Tekin , Isinsu Katircioglu , Mathieu Salzmann , Vincent Lepetit , Pascal Fua

Single particle cryo-electron microscopy has become a critical tool in structural biology over the last decade, able to achieve atomic scale resolution in three dimensional models from hundreds of thousands of (noisy) two-dimensional…

Numerical Analysis · Mathematics 2023-07-19 Aaditya V. Rangan , Leslie Greengard

Depth and ego-motion estimations are essential for the localization and navigation of autonomous robots and autonomous driving. Recent studies make it possible to learn the per-pixel depth and ego-motion from the unlabeled monocular video.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Guangming Wang , Jiquan Zhong , Shijie Zhao , Wenhua Wu , Zhe Liu , Hesheng Wang

Many imaging modalities involve reconstruction of unknown objects from collections of noisy projections related by random rotations. In one of these modalities, cryogenic electron microscopy (cryo-EM), the extremely low signal-to-noise…

Image and Video Processing · Electrical Eng. & Systems 2025-10-16 Joakim Andén , Justus Sagemüller

Single-particle cryo-EM has transformed structural biology but still faces challenges in resolving conformational heterogeneity at atomic resolution. Existing cryo-EM heterogeneity analysis methods either lack atomic details or tend to…

Biomolecules · Quantitative Biology 2025-10-21 Chengwei Zhang , Shimian Li , Yihao Niu , Zhen Zhu , Sihao Yuan , Sirui Liu , Yi Qin Gao

Robots rely on visual relocalization to estimate their pose from camera images when they lose track. One of the challenges in visual relocalization is repetitive structures in the operation environment of the robot. This calls for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Fereidoon Zangeneh , Leonard Bruns , Amit Dekel , Alessandro Pieropan , Patric Jensfelt

Clustering algorithms start with a fixed divergence, which captures the possibly asymmetric distance between a sample and a centroid. In the mixture model setting, the sample distribution plays the same role. When all attributes have the…

Machine Learning · Computer Science 2017-01-10 Mehmet Emin Basbug , Barbara Engelhardt

Deep Neural Networks trained as image auto-encoders have recently emerged as a promising direction for advancing the state-of-the-art in image compression. The key challenge in learning such networks is twofold: To deal with quantization,…

Computer Vision and Pattern Recognition · Computer Science 2019-06-05 Fabian Mentzer , Eirikur Agustsson , Michael Tschannen , Radu Timofte , Luc Van Gool

We introduce CHAMP, a novel method for learning sequence-to-sequence, multi-hypothesis 3D human poses from 2D keypoints by leveraging a conditional distribution with a diffusion model. To predict a single output 3D pose sequence, we…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Harry Zhang , Luca Carlone