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Quantifying the number of deaths caused by the COVID-19 crisis has been an ongoing challenge for scientists, and no golden standard to do so has yet been established. We propose a principled approach to calculate age-adjusted yearly excess…

Applications · Statistics 2023-12-20 Giacomo De Nicola , Göran Kauermann

Epidemic models play a key role in understanding and responding to the emerging COVID-19 pandemic. Widely used compartmental models are static and are of limited use to evaluate intervention strategies with the emerging pandemic. Applying…

Populations and Evolution · Quantitative Biology 2021-01-01 Shuo Wang , Xian Yang , Ling Li , Philip Nadler , Rossella Arcucci , Yuan Huang , Zhongzhao Teng , Yike Guo

We present a modified age-structured SIR model based on known patterns of social contact and distancing measures within Washington, USA. We find that population age-distribution has a significant effect on disease spread and mortality rate,…

Populations and Evolution · Quantitative Biology 2022-10-18 Vishaal Ram , Laura P. Schaposnik

Coronavirus Disease 2019 (COVID-19) is an emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with rapid human-to-human transmission and a high case fatality rate particularly in older…

In this paper we analyze the effects of commuting and social inequalities for the epidemic development of the novel coronavirus (COVID-19). With this aim we consider a SEIRD (susceptible, exposed, infected, recovered and dead by disease)…

Populations and Evolution · Quantitative Biology 2020-08-18 João A. M. Gondim , Thiago Yukio Tanaka

The COVID-19 pandemic has had worldwide devastating effects on human lives, highlighting the need for tools to predict its development. Dynamics of such public-health threats can often be efficiently analysed through simple models that help…

Populations and Evolution · Quantitative Biology 2021-06-04 Pedro L. de Andres , Lucia de Andres-Bragado , Linard D. Hoessly

The Covid-19 outbreak of 2020 has required many governments to develop and adopt mathematical-statistical models of the pandemic for policy and planning purposes. To this end, this work provides a tutorial on building a compartmental model…

Applications · Statistics 2023-09-13 Elizabeth B Amona , Ryad A Ghanam , Edward L Boone , Indranil Sahoo , Laith J Abu-Raddad

In this paper, we study the effectiveness of the modelling approach on the pandemic due to the spreading of the novel COVID-19 disease and develop a susceptible-infected-removed (SIR) model that provides a theoretical framework to…

Populations and Evolution · Quantitative Biology 2020-08-26 Ian Cooper , Argha Mondal , Chris G. Antonopoulos

In this paper, we apply statistical methods for functional data to explain the heterogeneity in the evolution of number of deaths of Covid-19 over different regions. We treat the cumulative daily number of deaths in a specific region as a…

Applications · Statistics 2021-09-07 Julian A. A. Collazos , Ronaldo Dias , Marcelo C. Medeiros

The viral load of patients infected with SARS-CoV-2 varies on logarithmic scales and possibly with age. Controversial claims have been made in the literature regarding whether the viral load distribution actually depends on the age of the…

Reliable mortality estimates at the subnational level are essential in the study of health inequalities within a country. One of the difficulties in producing such estimates is the presence of small populations, where the stochastic…

Applications · Statistics 2017-12-05 Monica Alexander , Emilio Zagheni , Magali Barbieri

This study aims to determine the demographic, epidemiologic, and clinical characteristics of COVID-19 cases that are highly susceptible to COVID-19 infection, with longer hospitalization and at higher risk of mortality and to provide…

Quantitative Methods · Quantitative Biology 2021-06-08 Roel F. Ceballos

We introduce a Bayesian sequential data assimilation method for COVID-19 forecasting. It is assumed that suitable transmission, epidemic and observation models are available and previously validated and the transmission and epidemic models…

In this paper, based on the Akaike information criterion, root mean square error and robustness coefficient, a rational evaluation of various epidemic models/methods, including seven empirical functions, four statistical inference methods…

Populations and Evolution · Quantitative Biology 2021-09-16 Wuyue Yang , Dongyan Zhang , Liangrong Peng , Changjing Zhuge , Liu Hong

We used Bayesian model inversion to estimate epidemic parameters from the reported case and death rates from seven countries using data from late January 2020 to April 5th 2020. Two distinct generative model types were employed: first a…

As of December 2020, the COVID-19 pandemic has infected over 75 million people, making it the deadliest pandemic in modern history. This study develops a novel compartmental epidemiological model specific to the SARS-CoV-2 virus and…

Populations and Evolution · Quantitative Biology 2021-11-19 Caden Lin

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

Physics and Society · Physics 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis

Raw data on the cumulative number of deaths at a country level generally indicate a spatially variable distribution of the incidence of COVID-19 disease. An important issue is to determine whether this spatial pattern is a consequence of…

Populations and Evolution · Quantitative Biology 2020-07-21 Lionel Roques , Olivier Bonnefon , Virgile Baudrot , Samuel Soubeyrand , Henri Berestycki

This study develops a framework for quantification of the impact of changes in population mobility due to social distancing on the COVID-19 infection growth rate. Using the Susceptible-Infected-Recovered (SIR) epidemiological model we…

Populations and Evolution · Quantitative Biology 2020-06-05 Benjamin Seibold , Zivjena Vucetic , Slobodan Vucetic

Analysing and understanding the transmission and evolution of the COVID-19 pandemic is mandatory to be able to design the best social and medical policies, foresee their outcomes and deal with all the subsequent socio-economic effects. We…

Populations and Evolution · Quantitative Biology 2025-07-28 Radu D. Stochiţoiu , Marian Petrica , Traian Rebedea , Ionel Popescu , Marius Leordeanu