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There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely…

Applications · Statistics 2022-06-08 Nicholas J. Irons , Adrian E. Raftery

COVID-19 has shown a relatively low mortality rate in young healthy individuals, with the majority of this group being asymptomatic or having mild symptoms, while the severity of the disease among individuals with underlying health…

Physics and Society · Physics 2020-06-22 Dario Ortega Anderez , Eiman Kanjo , Ganna Pogrebna , Shane Johnson , John Alan Hunt

Epidemiological forecasts are beset by uncertainties about the underlying epidemiological processes, and the surveillance process through which data are acquired. We present a Bayesian inference methodology that quantifies these…

In this article, we model and study the spread of COVID-19 in Germany, Japan, India and highly impacted states in India, i.e., in Delhi, Maharashtra, West Bengal, Kerala and Karnataka. We consider recorded data published in Worldometers and…

Physics and Society · Physics 2022-03-15 Ian Cooper , Argha Mondal , Chris G. Antonopoulos , Arindam Mishra

We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor class). We show that recording…

Understanding differences in hospital case-fatality rates (HCFRs) of coronavirus disease (COVID-19) may help evaluate its severity and the capacity of the healthcare system to reduce mortality. We examined the variability in HCFRs of…

The case fatality ratio (CFR) for COVID-19 is difficult to estimate. One difficulty is due to ignoring or overestimating time delay between reporting and death. We claim that all of these cause large errors and artificial time dependence of…

Populations and Evolution · Quantitative Biology 2020-07-02 Phoebus Rosakis , Maria Marketou

Strategies adopted globally to mitigate the threat of COVID-19 have primarily involved lockdown measures with substantial economic and social costs with varying degrees of success. Morbidity patterns of COVID-19 variants have a strong…

Populations and Evolution · Quantitative Biology 2022-01-19 Fatima-Zahra Jaouimaa , Daniel Dempsey , Suzanne van Osch , Stephen Kinsella , Kevin Burke , Jason Wyse , James Sweeney

To reduce the biases of traditional survey-based methods, this paper proposes an epidemic model-based approach to inference the incubation period distribution of COVID-19 utilizing the publicly reported confirmed case number. We construct…

Populations and Evolution · Quantitative Biology 2020-07-23 Shiyang Lai , Tianqi Zhao , Ningyuan Fan

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

Populations and Evolution · Quantitative Biology 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…

Applications · Statistics 2021-04-15 Claire Donnat , Susan Holmes

An epidemic disease caused by a new coronavirus has spread in Northern Italy with a strong contagion rate. We implement an SEIR model to compute the infected population and number of casualties of this epidemic. The example may ideally…

Populations and Evolution · Quantitative Biology 2020-05-12 Jose' M. Carcione , Juan E. Santos , Claudio Bagaini , Jing Ba

Following the emergence of a novel coronavirus (SARS-CoV-2) and its spread outside of China, Europe has experienced large epidemics. In response, many European countries have implemented unprecedented non-pharmaceutical interventions…

In this paper, we estimate the seroprevalence against COVID-19 by country and derive the seroprevalence over the world. To estimate seroprevalence, we use serological surveys (also called the serosurveys) conducted within each country. When…

Applications · Statistics 2022-02-01 Kwangmin Lee , Seongmin Kim , Seongil Jo , Jaeyong Lee

In this paper, we examine cross-country differences, in terms of the age distribution of symptomatic cases, hospitalizations, intensive care unit (ICU) cases, and fatalities due to the novel COVID-19. By calculating conditional…

Quantitative Methods · Quantitative Biology 2020-04-15 Enes Eryarsoy , Dursun Delen

This article presents a new model to predict the evolution of infective diseases under uncertainty or low-quality information, just as it has happened in the initial scenario during the CoVid-19 spread in China and Europe. The model has…

Other Quantitative Biology · Quantitative Biology 2020-04-14 Efren M. Benavides

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

This note considers the problem of conducting statistical inference on the share of individuals in some subgroup of a population that experience some event. The specific complication is that the size of the subgroup needs to be estimated,…

Applications · Statistics 2020-05-15 Christoph Rothe

As the ravages caused by COVID-19 pandemic are becoming inevitable with every moment, monitoring and understanding of transmission and fatality rate has become even more paramount for containing its spread. The key purpose of this analysis…

Populations and Evolution · Quantitative Biology 2020-08-12 Fakhar Mustafa , Rehan Ahmed Khan Sherwani , Syed Salman Saqlain , Muhammad Asad Meraj , Haseeb ur Rehman , Rida Ayyaz

Solid estimates describing the clinical course of SARS-CoV-2 infections are still lacking due to under-ascertainment of asymptomatic and mild-disease cases. In this work, we quantify age-specific probabilities of transitions between stages…