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We use a simple SIR-like epidemic model which integrates known age-contact patterns for the United States to model the effect of age-targeted mitigation strategies for a COVID-19-like epidemic. We find that, among strategies which end with…

Populations and Evolution · Quantitative Biology 2020-09-09 Maria Chikina , Wesley Pegden

As the COVID-19 pandemic evolves, reliable prediction plays an important role for policy making. The classical infectious disease model SEIR (susceptible-exposed-infectious-recovered) is a compact yet simplistic temporal model. The…

Machine Learning · Computer Science 2020-10-20 Yunling Zheng , Zhijian Li , Jack Xin , Guofa Zhou

At the time of writing, the ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had already resulted in more than thirty-two million cases infected and more than one million deaths worldwide.…

Optimization and Control · Mathematics 2023-03-22 Chung-Han Hsieh

Due to its impact, COVID-19 has been stressing the academy to search for curing, mitigating, or controlling it. However, when it comes to controlling, there are still few studies focused on under-reporting estimates. It is believed that…

Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population…

Quantitative Methods · Quantitative Biology 2021-12-28 Lucas Böttcher , Maria D'Orsogna , Tom Chou

Understanding the number of individuals who have been infected with the novel coronavirus SARS-CoV-2, and the extent to which social distancing policies have been effective at limiting its spread, are critical for effective policy going…

Applications · Statistics 2020-04-21 James Johndrow , Kristian Lum , Maria Gargiulo , Patrick Ball

We point out an instantiation of Simpson's paradox in Covid-19 case fatality rates (CFRs): comparing a large-scale study from China (17 Feb) with early reports from Italy (9 Mar), we find that CFRs are lower in Italy for every age group,…

Applications · Statistics 2021-06-24 Julius von Kügelgen , Luigi Gresele , Bernhard Schölkopf

COVID-19 is a new pandemic disease that is affecting almost every country with a negative impact on social life and economic activities. The number of infected and deceased patients continues to increase globally. Mathematical models can…

The outbreak of the novel coronavirus, COVID-19, has been declared a pandemic by the WHO. The structures of social contact critically determine the spread of the infection and, in the absence of vaccines, the control of these structures…

Populations and Evolution · Quantitative Biology 2020-03-27 Rajesh Singh , R. Adhikari

With the prevalence of COVID-19, the modeling of epidemic propagation and its analyses have played a significant role in controlling epidemics. However, individual behaviors, in particular the self-protection and migration, which have a…

Social and Information Networks · Computer Science 2025-11-25 Yuhan Li , Ziyan Zeng , Minyu Feng , Jürgen Kurths

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

Applications · Statistics 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

We provide a predictive analysis of the spread of COVID-19, also known as SARS-CoV-2, using the dataset made publicly available online by the Johns Hopkins University. Our main objective is to provide predictions of the number of infected…

Machine Learning · Computer Science 2020-05-26 Alireza M. Javid , Xinyue Liang , Arun Venkitaraman , Saikat Chatterjee

Qatar has undergone distinct waves of COVID-19 infections, compounded by the emergence of variants, posing additional complexities. This research uniquely delves into the varied efficacy of existing vaccines and the pivotal role of…

Applications · Statistics 2023-12-29 Elizabeth Amona , Indranil Sahoo , Edward Boone , Ryad Ghanam

The Covid-19 outbreak of 2020 has required many governments to develop mathematical-statistical models of the outbreak for policy and planning purposes. This work provides a tutorial on building a compartmental model using Susceptibles,…

Applications · Statistics 2020-05-27 Ryad Ghanam , Edward L. Boone , Abdel-Salam G. Abdel-Salam

In this paper, a mathematical model is proposed to analyze the dynamic behavior of COVID-19. Based on inter-city networked coupling effects, a fractional-order SEIHDR system with the real-data from 23 January to 18 March, 2020 of COVID-19…

Physics and Society · Physics 2020-05-01 Zhenzhen Lu , Yongguang Yu , YangQuan Chen , Guojian Ren , Conghui Xu , Shuhui Wang , Zhe Yin

In this paper, we introduce and study an age-structured epidemiological compartment model and its respective problem, applied but not limited to the COVID-19 pandemic, in order to investigate the role of the age of the individuals in the…

Dynamical Systems · Mathematics 2023-11-28 Vasiliki Bitsouni , Nikolaos Gialelis , Vasilis Tsilidis

Relevance: Laboratory diagnosis of the novel coronavirus (SARS-CoV-2) infection combined with quarantine for contacts of infected individuals affects the spread of SARS-CoV-2 infection and levels of related mortality. Practices for testing…

Populations and Evolution · Quantitative Biology 2020-10-27 Edward Goldstein

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

The number of new infections per day is a key quantity for effective epidemic management. It can be estimated relatively directly by testing of random population samples. Without such direct epidemiological measurement, other approaches are…

Applications · Statistics 2021-06-18 Simon N. Wood

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek
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