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Governments around the world aspire to ground decision-making on evidence. Many of the foundations of policy making - e.g. sensing patterns that relate to societal needs, developing evidence-based programs, forecasting potential outcomes of…

Artificial Intelligence · Computer Science 2023-12-12 Theodore Wolf , Nantas Nardelli , John Shawe-Taylor , Maria Perez-Ortiz

The immune system is a highly parallel and distributed intelligent system which has learning, memory, and associative capabilities. Artificial Immune System is an evolutionary paradigm inspired by the biological aspects of the immune system…

Cryptography and Security · Computer Science 2011-02-22 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

We propose a method of stacking multiple long short-term memory (LSTM) layers for modeling sentences. In contrast to the conventional stacked LSTMs where only hidden states are fed as input to the next layer, the suggested architecture…

Computation and Language · Computer Science 2019-11-04 Jihun Choi , Taeuk Kim , Sang-goo Lee

The similarity between neural and immune networks has been known for decades, but so far we did not understand the mechanism that allows the immune system, unlike associative neural networks, to recall and execute a large number of…

Disordered Systems and Neural Networks · Physics 2017-03-20 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari

This paper introduces Adaptive Mixture Importance Sampling (AMIS) as a novel approach for optimizing key performance indicators (KPIs) in large-scale recommender systems, such as online ad auctions. Traditional importance sampling (IS)…

Machine Learning · Computer Science 2024-09-23 Yimeng Jia , Kaushal Paneri , Rong Huang , Kailash Singh Maurya , Pavan Mallapragada , Yifan Shi

Foundation models have rapidly advanced AI, raising the question of whether their decisions will ultimately surpass human strategies in real-world domains. The exponential, and possibly super-exponential, pace of AI development makes such…

Machine Learning · Computer Science 2025-12-02 Moein E. Samadi , Andreas Schuppert

We introduce an approach for understanding control policies represented as recurrent neural networks. Recent work has approached this problem by transforming such recurrent policy networks into finite-state machines (FSM) and then analyzing…

Machine Learning · Computer Science 2021-07-13 Mohamad H. Danesh , Anurag Koul , Alan Fern , Saeed Khorram

The original Finite Selection Model (FSM) was developed in the 1970s to enhance the design of the RAND Health Insurance Experiment (HIE; Newhouse et al. 1993). At the time of its development by Carl Morris (Morris 1979), there were…

Methodology · Statistics 2021-05-07 Ambarish Chattopadhyay , Carl N. Morris , Jose R. Zubizarreta

Fine-tuning is widely applied in image classification tasks as a transfer learning approach. It re-uses the knowledge from a source task to learn and obtain a high performance in target tasks. Fine-tuning is able to alleviate the challenge…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Xuyang Shen , Jo Plested , Sabrina Caldwell , Yiran Zhong , Tom Gedeon

We argue that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It…

Populations and Evolution · Quantitative Biology 2008-01-08 E. Ahmed , A. H. Hashish

Agent-based simulators (ABS) are a popular epidemiological modelling tool to study the impact of various non-pharmaceutical interventions in managing an epidemic in a city (or a region). They provide the flexibility to accurately model a…

Physics and Society · Physics 2025-10-13 Daksh Mittal , Sandeep Juneja

Probabilistic models based on Restricted Boltzmann Machines (RBMs) imply the evaluation of normalized Boltzmann factors, which in turn require from the evaluation of the partition function Z. The exact evaluation of Z, though, becomes a…

Machine Learning · Computer Science 2020-07-24 Ferran Mazzanti , Enrique Romero

Understanding and modelling the complexity of the immune system is a challenge that is shared by the ImmunoComplexiT$^1$ thematic network from the RNSC. The immune system is a complex biological, adaptive, highly diversified, self-organized…

Quantitative Methods · Quantitative Biology 2020-08-27 Véronique Thomas-Vaslin

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Accurate cell counting in microscopic images is important for medical diagnoses and biological studies. However, manual cell counting is very time-consuming, tedious, and prone to subjective errors. We propose a new density regression-based…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shenghua He , Kyaw Thu Minn , Lilianna Solnica-Krezel , Hua Li , Mark Anastasio

Structured State Space Models (SSMs) have emerged as compelling alternatives to Transformer architectures, offering linear-time complexity and superior performance in various sequence modeling tasks. Despite their advantages, SSMs like the…

Computation and Language · Computer Science 2024-08-02 Tian Meng , Yang Tao , Wuliang Yin

Qualitative models provide crucial instruments for modelling complex biological systems. While advances in automated reasoning and symbolic encodings have enabled rigorous inference of these models from data, the process remains highly…

Molecular Networks · Quantitative Biology 2026-05-14 Ondřej Huvar , Nikola Beneš , Martin Jonáš , David Šafránek , Samuel Pastva

Model-based Testing (MBT) is an effective approach for testing when parts of a system-under-test have the characteristics of a finite state machine (FSM). Despite various strategies in the literature on this topic, little work exists to…

Software Engineering · Computer Science 2022-04-05 Vaclav Rechtberger , Miroslav Bures , Bestoun S. Ahmed , Youcef Belkhier , Jiri Nema , Hynek Schvach

A number of works in the field of intrusion detection have been based on Artificial Immune System and Soft Computing. Artificial Immune System based approaches attempt to leverage the adaptability, error tolerance, self- monitoring and…

Cryptography and Security · Computer Science 2012-05-22 Sugata Sanyal , Manoj Rameshchandra Thakur

While reinforcement learning from scratch has shown impressive results in solving sequential decision-making tasks with efficient simulators, real-world applications with expensive interactions require more sample-efficient agents.…

Machine Learning · Computer Science 2025-09-22 Remo Sasso , Michelangelo Conserva , Dominik Jeurissen , Paulo Rauber