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Mental disorders represent a critical global health challenge, and social media is increasingly viewed as a vital resource for real-time digital phenotyping and intervention. To leverage this data, large language models (LLMs) have been…

Computation and Language · Computer Science 2025-12-23 Zhuohan Ge , Darian Li , Yubo Wang , Nicole Hu , Xinyi Zhu , Haoyang Li , Xin Zhang , Mingtao Zhang , Shihao Qi , Yuming Xu , Han Shi , Chen Jason Zhang , Qing Li

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Multimodal large language models (MLLMs) have emerged as a promising paradigm for dental image analysis. However, their ability to capture the multi-level cognitive processes required for radiographic analysis remains unclear. Here, we…

Computation and Language · Computer Science 2026-05-11 Rongyang Wang , Shuang Zhou , Jiashuo Wang , Wenya Xie , Xiaoxia Che

Depression is a widespread mental disorder that affects millions worldwide. While automated depression assessment shows promise, most studies rely on limited or non-clinically validated data, and often prioritize complex model design over…

Computation and Language · Computer Science 2025-08-07 Zhuang Chen , Guanqun Bi , Wen Zhang , Jiawei Hu , Aoyun Wang , Xiyao Xiao , Kun Feng , Minlie Huang

Large language models (LLMs) exhibit remarkable similarity to neural activity in the human language network. However, the key properties of language shaping brain-like representations, and their evolution during training as a function of…

Computation and Language · Computer Science 2025-09-23 Badr AlKhamissi , Greta Tuckute , Yingtian Tang , Taha Binhuraib , Antoine Bosselut , Martin Schrimpf

The escalating global mental health crisis, marked by persistent treatment gaps, availability, and a shortage of qualified therapists, positions Large Language Models (LLMs) as a promising avenue for scalable support. While LLMs offer…

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large language models, such as GPT-4 and Med-PaLM, have shown impressive performance on clinical tasks; however, they require access to compute, are closed-source, and cannot be deployed on device. Mid-size models such as BioGPT-large,…

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Large Language Models (LLMs) have shown significant potential in understanding human communication and interaction. However, their performance in the domain of child-inclusive interactions, including in clinical settings, remains less…

Computation and Language · Computer Science 2024-11-19 Tiantian Feng , Anfeng Xu , Rimita Lahiri , Helen Tager-Flusberg , So Hyun Kim , Somer Bishop , Catherine Lord , Shrikanth Narayanan

Mental health disorders pose a growing public health concern in the Arab world, emphasizing the need for accessible diagnostic and intervention tools. Large language models (LLMs) offer a promising approach, but their application in Arabic…

Computation and Language · Computer Science 2025-01-14 Noureldin Zahran , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

The relationship between communicated language and intended meaning is often probabilistic and sensitive to context. Numerous strategies attempt to estimate such a mapping, often leveraging recursive Bayesian models of communication. In…

Computation and Language · Computer Science 2023-05-03 Benjamin Lipkin , Lionel Wong , Gabriel Grand , Joshua B Tenenbaum

Language Models (LMs) are being proposed for mental health applications where the heightened risk of adverse outcomes means predictive performance may not be a sufficient litmus test of a model's utility in clinical practice. A model that…

Artificial Intelligence · Computer Science 2024-12-05 Seyedali Mohammadi , Edward Raff , Jinendra Malekar , Vedant Palit , Francis Ferraro , Manas Gaur

Large Language Models (LLMs) are becoming widely used to support various workflows across different disciplines, yet their potential in discrete choice modelling remains relatively unexplored. This work examines the potential of LLMs as…

Econometrics · Economics 2026-03-18 Georges Sfeir , Gabriel Nova , Stephane Hess , Sander van Cranenburgh

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients,…

Artificial Intelligence · Computer Science 2025-10-30 Eranga Bandara , Ross Gore , Atmaram Yarlagadda , Anita H. Clayton , Preston Samuel , Christopher K. Rhea , Sachin Shetty

Large Language Models (LLMs) have demonstrated remarkable abilities in text comprehension and logical reasoning, indicating that the text representations learned by LLMs can facilitate their language processing capabilities. In…

Artificial Intelligence · Computer Science 2025-01-16 Yuqi Ren , Renren Jin , Tongxuan Zhang , Deyi Xiong

Large Language Models (LLMs) are transforming mental health care by enhancing accessibility, personalization, and efficiency in therapeutic interventions. These AI-driven tools empower mental health professionals with real-time support,…

Computers and Society · Computer Science 2025-01-22 Hari Mohan Pandey

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Large Language Models (LLMs) have demonstrated surprising performance on many tasks, including writing supportive messages that display empathy. Here, we had these models generate empathic messages in response to posts describing common…

Computation and Language · Computer Science 2024-03-28 Yoon Kyung Lee , Jina Suh , Hongli Zhan , Junyi Jessy Li , Desmond C. Ong