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The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…

Soft Condensed Matter · Physics 2019-02-27 Pierra A. Haas , Raymond E. Goldstein

In many biological systems, motile agents exhibit random motion with short-term directional persistence, together with crowding effects arising from spatial exclusion. We formulate and study a class of lattice-based models for multiple…

Biological Physics · Physics 2019-11-06 Stephen Zhang , Aaron Chong , Barry D. Hughes

Clouds play a central role in climate physics by interacting with precipitation, radiation, and circulation. Despite being a fundamental issue in convective organization, the self-aggregation of clouds lacks a theoretical explanation due to…

Atmospheric and Oceanic Physics · Physics 2026-05-19 Tomoro Yanase , Shin-ichiro Shima , Seiya Nishizawa , Hirofumi Tomita

Partial differential equation (PDE) models for infectious disease have received renewed interest in recent years. Most models of this type extend classical compartmental formulations with additional terms accounting for spatial dynamics,…

Populations and Evolution · Quantitative Biology 2025-04-29 Pierluigi Colli , Gabriela Marinoschi , Elisabetta Rocca , Alex Viguerie

The data-driven models allow one to define the model structure in cases when a priori information is not sufficient to build other types of models. The possible way to obtain physical interpretation is the data-driven differential equation…

Neural and Evolutionary Computing · Computer Science 2019-06-11 Michail Maslyaev , Alexander Hvatov , Anna Kalyuzhnaya

We study a class of nonlocal, energy-driven dynamical models that govern the motion of closed, embedded curves from both an energetic and dynamical perspective. Our energetic results provide a variety of ways to understand physically…

Analysis of PDEs · Mathematics 2017-11-29 James H. von Brecht , Ryan Blair

One of the fundamental problems in biology concerns the method by which a cluster of organisms can regulate the proportion of individuals that perform various roles or modes as if each individual knows a whole situation without a leader. A…

Adaptation and Self-Organizing Systems · Physics 2015-12-21 Mayuko Iwamoto , Daishin Ueyama

Natural phenomena frequently involve a very large number of interacting molecules moving in confined regions of space. Cellular transport by motor proteins is an example of such collective behavior. We derive a deterministic compartmental…

Subcellular Processes · Quantitative Biology 2017-11-01 Yoram Zarai , Michael Margaliot , Anatoly B. Kolomeisky

We describe a continuous-time modelling framework for biological population dynamics that accounts for demographic noise. In the spirit of the methodology used by statistical physicists, transitions between the states of the system are…

Populations and Evolution · Quantitative Biology 2018-07-19 George W. A. Constable , Alan J. McKane

Collective cell migration is a multicellular phenomenon that arises in various biological contexts, including cancer and embryo development. "Collectiveness" can be promoted by cell-cell interactions such as co-attraction and contact…

Cell Behavior · Quantitative Biology 2023-10-03 Viktoria Freingruber , Kevin J. Painter , Mariya Ptashnyk , Linus Schumacher

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

Phenotypically structured equations arise in population biology to describe the interaction of species with their environment that brings the nutrients. This interaction usually leads to selection of the fittest individuals. Models used in…

Analysis of PDEs · Mathematics 2015-06-18 Alexander Lorz , Benoit Perthame

We explore analytically and numerically agglomeration driven by advection and localized source. The system is inhomogeneous in one dimension, viz. along the direction of advection. We analyze a simplified model with mass-independent…

The biological theory of adaptive dynamics proposes a description of the long-term evolution of a structured asexual population. It is based on the assumptions of large population, rare mutations and small mutation steps, that lead to a…

Probability · Mathematics 2007-05-23 Nicolas Champagnat , Amaury Lambert

With the influx of complex and detailed tracking data gathered from electronic tracking devices, the analysis of animal movement data has recently emerged as a cottage industry amongst biostatisticians. New approaches of ever greater…

Applications · Statistics 2017-01-31 Toby A Patterson , Alison Parton , Roland Langrock , Paul G Blackwell , Len Thomas , Ruth King

In this paper we study some mathematical models describing evolution of population density and spread of epidemics in population systems in which spatial movement of individuals depends only on the departure and arrival locations and does…

Functional Analysis · Mathematics 2014-03-24 Shangbin Cui , Meng Bai

We classify and predict the asymptotic dynamics of a class of swarming models. The model consists of a conservation equation in one dimension describing the movement of a population density field. The velocity is found by convolving the…

Populations and Evolution · Quantitative Biology 2015-05-13 A. J. Leverentz , C. M. Topaz , A. J. Bernoff

Partial differential equation (PDE) models for infectious diseases, while less common than their ordinary differential equation (ODE) counterparts, have found successful applications for many years. Such models are typically of…

Populations and Evolution · Quantitative Biology 2026-01-27 Alex Viguerie , Malú Grave , Alvaro L. G. A. Coutinho , Alessandro Veneziani , Thomas J. R. Hughes

It is very important to understand urban mobility patterns because most trips are concentrated in urban areas. In the paper, a new model is proposed to model collective human mobility in urban areas. The model can be applied to predict…

Physics and Society · Physics 2014-10-28 Xiao Liang , Jichang Zhao , Li Dong , Ke Xu

We present a new class of macroscopic models for pedestrian flows. Each individual is assumed to move towards a fixed target, deviating from the best path according to the instantaneous crowd distribution. The resulting equation is a…

Analysis of PDEs · Mathematics 2011-04-21 Rinaldo M. Colombo , Mauro Garavello , Magali Lécureux-Mercier