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Cell-cell adhesion is an inherently nonlocal phenomenon. Numerous partial differential equation models with nonlocal term have been recently presented to describe this phenomenon, yet the mathematical properties of nonlocal adhesion model…

Analysis of PDEs · Mathematics 2021-03-17 Jaewook Ahn , Myeongju Chae , Jihoon Lee

We consider a couple of models for the dynamics of the populations of two interacting species, inspired by Lotka-Volterra's classical equations. The novelty of this work is that the interaction terms are non local and the interaction occurs…

Populations and Evolution · Quantitative Biology 2022-09-21 Mario I. Simoy , Marcelo N. Kuperman

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

Advective trapping occurs when solute enters low velocity zones in heterogeneous porous media. Classical local modeling approaches combine the impact of slow advection and diffusion into a hydrodynamic dispersion coefficient and many…

Fluid Dynamics · Physics 2020-12-02 Juan J. Hidalgo , Insa Neuweiler , Marco Dentz

The transition from a microscopic model for the movement of many particles to a macroscopic continuum model for a density flow is studied. The microscopic model for the free flow is completely deterministic, described by an interaction…

Statistical Mechanics · Physics 2021-01-12 Jennifer Weissen , Simone Göttlich , Dieter Armbruster

In this paper, we inspect well-known population genetics and social dynamics models. In these models, interacting individuals, while participating in a self-organizing process, give rise to the emergence of complex behaviors and patterns.…

Populations and Evolution · Quantitative Biology 2012-07-11 Sven Banisch , Tanya Araújo

With the aim of understanding the emergence of collective motion from local interactions of organisms in a "noisy" environment, we study biologically inspired, inherently non-equilibrium models consisting of self-propelled particles. In…

Biological Physics · Physics 2009-10-31 A. Czirok , T. Vicsek

It has been shown experimentally that contact interactions may influence the migration of cancer cells. Previous works have modelized this thanks to stochastic, discrete models (cellular automata) at the cell level. However, for the study…

Cell Behavior · Quantitative Biology 2009-03-26 Christophe Deroulers , Marine Aubert , Mathilde Badoual , Basil Grammaticos

In this paper we analyze a new temperature-dependent model for adhesive contact that encompasses nonlocal adhesive forces and damage effects, as well as nonlocal heat flux contributions on the contact surface. The related PDE system…

Analysis of PDEs · Mathematics 2021-04-13 Giovanna Bonfanti , Michele Colturato , Riccarda Rossi

We adapt a fitness function from evolutionary game theory as a mechanism for aggregation and dispersal in a partial differential equation (PDE) model of two interacting populations, described by density functions $u$ and $v$. We consider a…

Populations and Evolution · Quantitative Biology 2018-03-16 Russ deForest , Andrew Belmonte

We propose a (time) multiscale method for the coarse-grained analysis of self--propelled particle models of swarms comprising a mixture of `na\"{i}ve' and `informed' individuals, used to address questions related to collective motion and…

Populations and Evolution · Quantitative Biology 2012-02-28 Michael Raghib , Simon A. Levin , Ioannis G. Kevrekidis

There has been increasing experimental evidence of non-affine elastic deformation mechanisms in biological soft tissues. These observations call for novel constitutive models which are able to describe the dominant underlying…

Computational Physics · Physics 2021-03-04 Sebastian Skatulla , Carlo Sansour , Georges Limbert

Discrete time, spatially extended models play an important role in ecology, modelling population dynamics of species ranging from micro-organisms to birds. An important question is how 'bottom up', individual-based models can be…

Populations and Evolution · Quantitative Biology 2023-01-20 Linnéa Gyllingberg , David J. T. Sumpter , Åke Brännström

The notions of taxis and kinesis are introduced and used to describe two types of behavior of an organism in non-uniform conditions: (i) Taxis means the guided movement to more favorable conditions; (ii) Kinesis is the non-directional…

Populations and Evolution · Quantitative Biology 2018-12-06 A. N. Gorban , N. Çabukoǧlu

The mechanisms driving the collective movement of cells remain poorly understood. To contribute toward resolving this mystery, a model was formulated to theoretically explore the possible functions of polarized cell-cell adhesion in…

Biological Physics · Physics 2018-04-25 Katsuyoshi Matsushita

Nonlocal conservation laws are used to describe various realistic instances of crowd behaviors. First, a basic analytic framework is established through an "ad hoc" well posedness theorem for systems of nonlocal conservation laws in several…

Analysis of PDEs · Mathematics 2015-06-19 Raul Borsche , Rinaldo M. Colombo , Mauro Garavello , Anne Meurer

Complex biological processes involve collective behavior of entities (bacteria, cells, animals) over many length and time scales and can be described by discrete models that track individuals or by continuum models involving densities and…

Soft Condensed Matter · Physics 2023-11-16 F. Terragni , W. D. Martinson , M. Carretero , P. K. Maini , L. L. Bonilla

Adhesion between cells plays an important role in many biological processes such as tissue morphogenesis and homeostasis, wound healing and cancer cell metastasis. From a mathematical perspective, adhesion between multiple cell types has…

Cell Behavior · Quantitative Biology 2024-04-17 Shahzeb Raja Noureen , Richard L. Mort , Christian A. Yates

In many scientific fields, the generation and evolution of data are governed by partial differential equations (PDEs) which are typically informed by established physical laws at the macroscopic level to describe general and predictable…

Methodology · Statistics 2025-07-01 Ziyuan Chen , Shunxing Yan , Fang Yao

In this work, we introduce a novel first-order nonlocal partial differential equation with saturated diffusion to describe the macroscopic behavior of traffic dynamics. We show how the proposed model is better in comparison with existing…

Optimization and Control · Mathematics 2025-04-02 Dawson Do , Hossein Nick Zinat Matin , Masuma Mollika Miti , Maria Laura Delle Monache
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