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This survey focuses on the most important aspects of the mathematical theory of population genetic models of selection and migration between discrete niches. Such models are most appropriate if the dispersal distance is short compared to…

Populations and Evolution · Quantitative Biology 2019-12-13 Reinhard Bürger

Understanding how stochastic and non-linear deterministic processes interact is a major challenge in population dynamics theory. After a short review, we introduce a stochastic individual-centered particle model to describe the evolution in…

Probability · Mathematics 2009-06-29 Regis Ferriere , Viet Chi Tran

We study dynamics emergent from a two-dimensional reaction--diffusion process modelled via a finite lattice dynamical system, as well as an analogous PDE system, involving spatially nonlocal interactions. These models govern the evolution…

Tissues and Organs · Quantitative Biology 2018-11-14 Andrew L. Krause , Dmitry Beliaev , Robert A. Van Gorder , Sarah L. Waters

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Reaction-diffusion models are used to describe systems in fields as diverse as physics, chemistry, ecology and biology. The fundamental quantities in such models are individual entities such as atoms and molecules, bacteria, cells or…

Computational Physics · Physics 2016-03-02 Fabian Spill , Pilar Guerrero , Tomas Alarcon , Philip K. Maini , Helen Byrne

In this paper, we propose and study several inverse problems of determining unknown parameters in nonlocal nonlinear coupled PDE systems, including the potentials, nonlinear interaction functions and time-fractional orders. In these coupled…

Analysis of PDEs · Mathematics 2024-07-23 Ming-Hui Ding , Hongyu Liu , Catharine W. K. Lo

We study the emergence of the collective spatio-temporal macroscopic properties of the immune system, by representing individually the elementary interactions between its microscopic components (antibodies, antigens, cytokines). The results…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun. R. Cohen

Migrating cells choose their preferential direction of motion in response to different signals and stimuli sensed by spanning their external environment. However, the presence of dense fibrous regions, lack of proper substrate, and cell…

Cell Behavior · Quantitative Biology 2019-08-23 Nadia Loy , Luigi Preziosi

The strong Allee effect plays an important role on the evolution of population in ecological systems. One important concept is the Allee threshold that determines the persistence or extinction of the population in a long time. In general, a…

Analysis of PDEs · Mathematics 2024-08-05 Fanze Kong , Juncheng Wei

As a nonlocal extension of continuum mechanics, peridynamics has been widely and effectively applied in different fields where discontinuities in the field variables arise from an initially continuous body. An important component of the…

Numerical Analysis · Mathematics 2021-09-22 Xiao Xu , Marta D'Elia , John T. Foster

The brain-body-environment framework studies adaptive behavior through embodied and situated agents, emphasizing interactions between brains, biomechanics, and environmental dynamics. However, many models often treat the brain as a network…

Neurons and Cognition · Quantitative Biology 2025-10-01 Denizhan Pak , Quan Le Thien , Christopher J. Agostino

We study molecular dynamics within populations of diffusively coupled cells under the assumption of fast diffusive exchange. As a technical tool, we propose conditions on boundedness and ultimate boundedness for systems with a singular…

Cell Behavior · Quantitative Biology 2012-12-19 Steffen Waldherr , Frank Allgöwer

We study a stochastic epidemic model with multiple patches (locations), where individuals in each patch are categorized into three compartments, Susceptible, Infected and Recovered/Removed, and may migrate from one patch to another in any…

Probability · Mathematics 2023-08-21 Guodong Pang , Etienne Pardoux

Ecologists have long investigated how demographic and movement parameters determine the spatial distribution and critical habitat size of a population. However, most models oversimplify movement behavior, neglecting how landscape…

Populations and Evolution · Quantitative Biology 2024-03-11 Vivian Dornelas , Pablo de Castro , Justin M. Calabrese , William F. Fagan , Ricardo Martinez-Garcia

Persistence of motion is the tendency of an object to maintain motion in a direction for short time scales without necessarily being biased in any direction in the long term. One of the most appropriate mathematical tools to study this…

Soft Condensed Matter · Physics 2018-04-04 Enrico Gavagnin , Christian A. Yates

This paper is concerned with mathematical modeling of intelligent systems, such as human crowds and animal groups. In particular, the focus is on the emergence of different self-organized patterns from non-locality and anisotropy of the…

Mathematical Physics · Physics 2010-09-07 Emiliano Cristiani , Benedetto Piccoli , Andrea Tosin

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Two phase solid-fluid mixture models are ubiquitous in biological applications. For instance, models for growth of tissues and biofilms combine time dependent and quasi-stationary boundary value problems set in domains whose boundary moves…

Analysis of PDEs · Mathematics 2024-01-17 Ana Carpio , Gema Duro

The dispersal of cells from an initially constrained location is a crucial aspect of many physiological phenomena ranging from morphogenesis to tumour spreading. In such processes, the way cell-cell interactions impact the motion of single…

We introduce a generic, purely mechanical model for environment sensitive motion of mammalian cells that is applicable to chemotaxis, haptotaxis, and durotaxis as modes of motility. It is able to theoretically explain all relevant…

Cell Behavior · Quantitative Biology 2016-05-09 Patrick Bitter , Kristof Leon Beck , Peter Lenz