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Lobar cerebral microbleeds (CMBs) and localized non-hemorrhage iron deposits in the basal ganglia have been associated with brain aging, vascular disease and neurodegenerative disorders. Particularly, CMBs are small lesions and require…

We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Aaron Pries , Peter J. Schreier , Artur Lamm , Stefan Pede , Jürgen Schmidt

Vertebral body compression fractures are reliable early signs of osteoporosis. Though these fractures are visible on Computed Tomography (CT) images, they are frequently missed by radiologists in clinical settings. Prior research on…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Maxim Pisov , Vladimir Kondratenko , Alexey Zakharov , Alexey Petraikin , Victor Gombolevskiy , Sergey Morozov , Mikhail Belyaev

Degenerative discopathy is a common pathology which may require spine surgery. A metallic cylindrical pin is inserted into the vertebral body to maintain soft tissues and may be used as a reflector of ultrasonic wave to estimate bone…

Estimating the marginal and joint densities of the long-term average intakes of different dietary components is an important problem in nutritional epidemiology. Since these variables cannot be directly measured, data are usually collected…

Methodology · Statistics 2022-05-18 Abhra Sarkar

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 David Butler , Adrian Hilton , Gustavo Carneiro

Segmentation of bone regions allows for enhanced diagnostics, disease characterisation and treatment monitoring in CT imaging. In contrast enhanced whole-body scans accurate automatic segmentation is particularly difficult as low dose whole…

Medical Physics · Physics 2020-08-14 Patrick Leydon , Martin O'Connell , Derek Greene , Kathleen M Curran

Osteosarcoma is the most common primary bone cancer, mainly affecting the youngest and oldest populations. Its detection at early stages is crucial to reduce the probability of developing bone metastasis. In this context, accurate and fast…

Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

Medical Physics · Physics 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

Accurate prediction of knee osteoarthritis (KOA) progression from structural MRI has a potential to enhance disease understanding and support clinical trials. Prior art focused on manually designed imaging biomarkers, which may not fully…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Plain X-ray is one of the most common image modalities for clinical diagnosis (e.g. bone fracture, pneumonia, cancer screening, etc.). X-ray image segmentation is an essential step for many computer-aided diagnostic systems, yet it remains…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Youssef ElTantawy , Alexia Karantana , Xin Chen

We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…

Background: MR-based subchondral bone effectively predicts knee osteoarthritis. However, its clinical application is limited by the cost and time of MR. Purpose: We aim to develop a novel distillation-learning-based method named SRRD for…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Yuqi Hu , Xiangyu Zhao , Gaowei Qing , Kai Xie , Chenglei Liu , Lichi Zhang

Intravital X-ray microscopy (XRM) in preclinical mouse models is of vital importance for the identification of microscopic structural pathological changes in the bone which are characteristic of osteoporosis. The complexity of this method…

Quantitative bone single-photon emission computed tomography (QBSPECT) has the potential to provide a better quantitative assessment of bone metastasis than planar bone scintigraphy due to its ability to better quantify activity in…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Junyu Chen , Ye Li , Licia P. Luna , Hyun Woo Chung , Steven P. Rowe , Yong Du , Lilja B. Solnes , Eric C. Frey

Bone segmentation is an essential step for the preoperative planning of fracture trauma surgery. The automated segmentation of fractured bone from computed tomography (CT) scans remains challenging, due to the large differences of fractures…

Computer Vision and Pattern Recognition · Computer Science 2024-05-03 Yu Zhou , Xiahao Zou , Yi Wang

The present research tackles the difficulty of predicting osteoporosis risk via machine learning (ML) approaches, emphasizing the use of explainable artificial intelligence (XAI) to improve model transparency. Osteoporosis is a significant…

Machine Learning · Computer Science 2025-10-03 Farhana Elias , Md Shihab Reza , Muhammad Zawad Mahmud , Samiha Islam , Shahran Rahman Alve

Lung diseases represent a significant global health challenge, with Chest X-Ray (CXR) being a key diagnostic tool due to its accessibility and affordability. Nonetheless, the detection of pulmonary lesions is often hindered by overlapping…

Image and Video Processing · Electrical Eng. & Systems 2025-07-10 Yifei Sun , Zhanghao Chen , Hao Zheng , Wenming Deng , Jin Liu , Wenwen Min , Ahmed Elazab , Xiang Wan , Changmiao Wang , Ruiquan Ge

Osteosarcoma, the most common primary bone cancer, often requires accurate necrosis assessment from whole slide images (WSIs) for effective treatment planning and prognosis. However, manual assessments are subjective and prone to…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Manh Duong Nguyen , Dac Thai Nguyen , Trung Viet Nguyen , Homi Yamada , Huy Hieu Pham , Phi Le Nguyen

Computer-aided diagnosis (CAD) is today considered a vital tool in the field of biological image categorization, segmentation, and other related tasks. The current breakthrough in computer vision algorithms and deep learning approaches has…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Sayeda Sanzida Ferdous Ruhi , Fokrun Nahar , Adnan Ferdous Ashrafi