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Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA), which quantifies areal bone mineral density but overlooks bone microarchitecture and surrounding soft tissues. High-resolution peripheral…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Mohseu Rashid Subah , Mohammed Abdul Gani Zilani , Thomas L. Nickolas , Matthew R. Allen , Stuart J. Warden , Rachel K. Surowiec

Osteoporosis silently erodes skeletal integrity worldwide; however, early detection through imaging can prevent most fragility fractures. Artificial intelligence (AI) methods now mine routine Dual-energy X-ray Absorptiometry (DXA), X-ray,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-02 Abdul Rahman , Bumshik Lee

Osteoporosis, a major global epidemic, often goes undetected until a fracture occurs, largely due to poor access to screening using gold standard methods, such as dual-energy X-ray absorptiometry (DXA). As a potential nonionizing radiation…

Medical Physics · Physics 2026-03-20 Mohammad Hosseini , Sadia Afrin , Anthony Yosick , Hani Awad , Andrew J. Berger

Osteoporosis and osteopenia remain vastly underdiagnosed. Current clinical screening relies almost exclusively on dual-energy X-ray absorptiometry (DXA), which measures bone mineral density (BMD) but fails to capture the compositional…

Medical Physics · Physics 2025-10-29 Mohammad Hosseini , Sadia Afrin , Anthony Yosick , Emma Schenker , Hani Awad , Andrew J. Berger

Osteoporosis is a skeletal disorder that leads to increased fracture risk due to decreased strength of cortical and trabecular bone. Even with state-of-the-art non-invasive assessment methods there is still a high underdiagnosis rate.…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Stefan Reinhold , Timo Damm , Sebastian Büsse , Stanislav N. Gorb , Claus-C. Glüer , Reinhard Koch

Bone marrow lesions (BMLs) are critical indicators of knee osteoarthritis (OA). Since they often appear as small, irregular structures with indistinguishable edges in knee magnetic resonance images (MRIs), effective detection of BMLs in MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Shihua Qin , Ming Zhang , Juan Shan , Taehoon Shin , Jonghye Woo , Fangxu Xing

Background: Osteoporosis and osteopenia are often undiagnosed until fragility fractures occur. Dual-energy X-ray absorptiometry (DXA) is the reference standard for bone mineral density (BMD) assessment, but access remains limited. Knee…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Zhaochen Li , Xinghao Yan , Runni Zhou , Xiaoyang Li , Chenjie Zhu , Gege Wang , Yu Shi , Lixin Zhang , Rongrong Fu , Liehao Yan , Yuan Chai

The diagnosis of primary bone tumors is challenging, as the initial complaints are often non-specific. Early detection of bone cancer is crucial for a favorable prognosis. Incidentally, lesions may be found on radiographs obtained for other…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Tal Zimbalist , Ronnie Rosen , Keren Peri-Hanania , Yaron Caspi , Bar Rinott , Carmel Zeltser-Dekel , Eyal Bercovich , Yonina C. Eldar , Shai Bagon

Low bone mineral density (BMD) is believed to influence the outcome of instrumented spinal surgery and can lead to reoperation. Purpose of this observational and case-control study was to investigate the association of BMD with the risk of…

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

Osteoporosis can be identified by looking at 2D x-ray images of the bone. The high degree of similarity between images of a healthy bone and a diseased one makes classification a challenge. A good bone texture characterization technique is…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Rahul Paul , Saeed Alahamri , Sulav Malla , Ghulam Jilani Quadri

Dual energy CT (DECT) enhances tissue characterization because it can produce images of basis materials such as soft-tissue and bone. DECT is of great interest in applications to medical imaging, security inspection and nondestructive…

Medical Physics · Physics 2018-09-05 Qiaoqiao Ding , Tianye Niu , Xiaoqun Zhang , Yong Long

Purpose: Proximal femur image analyses based on quantitative computed tomography (QCT) provide a method to quantify the bone density and evaluate osteoporosis and risk of fracture. We aim to develop a deep-learning-based method for…

Bone health studies are crucial in medical practice for the early detection and treatment of Osteopenia and Osteoporosis. Clinicians usually make a diagnosis based on densitometry (DEXA scans) and patient history. The applications of AI in…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Alvaro Lopez Pellicer , Andre Mariucci , Plamen Angelov , Marwan Bukhari , Jemma G. Kerns

In this paper, we present a deep-learning based method for estimating the 3D structure of a bone from a pair of 2D X-ray images. Our triplet loss-trained neural network selects the most closely matching 3D bone shape from a predefined set…

Computer Vision and Pattern Recognition · Computer Science 2020-10-12 Jana Čavojská , Julian Petrasch , Nicolas J. Lehmann , Agnès Voisard , Peter Böttcher

Bone marrow (BM) metabolic quantification with 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is of broad clinical significance for accurate assessment of BM at staging and follow-up, especially when immunotherapy is…

We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling…

Logic in Computer Science · Computer Science 2011-11-10 Pietro Liò , Emanuela Merelli , Nicola Paoletti

Quantitative computed tomography (QCT) is a widely used tool for osteoporosis diagnosis and monitoring. The assessment of cortical markers like cortical bone mineral density (BMD) and thickness is a demanding task, mainly because of the…

Image and Video Processing · Electrical Eng. & Systems 2019-02-18 Stefan Reinhold. Timo Damm , Lukas Huber , Reimer Andresen , Reinhard Barkmann , Claus-C. Glüer , Reinhard Koch

Bones are always wrapped by soft tissues. As a result, bones in their X-ray images are obscured and become unclear. In this paper, we tackle this problem and propose a novel task to virtually decompose the soft tissue and bone by image…

Image and Video Processing · Electrical Eng. & Systems 2020-07-30 Yuanhao Gong

Chest X-rays (CXRs) are commonly utilized as a low-dose modality for lung screening. Nonetheless, the efficacy of CXRs is somewhat impeded, given that approximately 75% of the lung area overlaps with bone, which in turn hampers the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Zhanghao Chen , Yifei Sun , Wenjian Qin , Ruiquan Ge , Cheng Pan , Wenming Deng , Zhou Liu , Wenwen Min , Ahmed Elazab , Xiang Wan , Changmiao Wang