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Large language models (LLMs) struggle in real-world clinical consultations. Single-turn consultation systems require patients to describe all symptoms at once, which often leads to unclear complaints and vague diagnoses. Traditional…

Computation and Language · Computer Science 2026-05-01 Yichun Feng , Jiawei Wang , Lu Zhou , Yikai Zheng , Zhen Lei , Yixue Li

The role played by physical activity in slowing down the progression of type-2 diabetes is well recognized. However, except for general clinical guidelines, quantitative real-time estimates of the recommended amount of physical activity,…

Systems and Control · Electrical Eng. & Systems 2025-03-13 Pierluigi Francesco De Paola , Alessandro Borri , Alessia Paglialonga , Pasquale Palumbo , Fabrizio Dabbene

Machine learning shows remarkable success for recognizing patterns in data. Here we apply the machine learning (ML) for the diagnosis of early stage diabetes, which is known as a challenging task in medicine. Blood glucose levels are…

Quantitative Methods · Quantitative Biology 2021-02-24 Woo Seok Lee , Junghyo Jo , Taegeun Song

Type 2 diabetes prevention and treatment can benefit from personalized lifestyle prescriptions. However, the delivery of personalized lifestyle medicine prescriptions is limited by the shortage of trained professionals and the variability…

Applications · Statistics 2025-11-03 Yuhan Tang

This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes…

Systems and Control · Electrical Eng. & Systems 2025-03-11 Omar Mameche , Abdelhadi Abedou , Taqwa Mezaache , Mohamed Tadjine

This paper presents a Vehicle-to-Grid (V2G) coordination framework using reinforcement learning (RL). {An intelligent control strategy based on the soft actor-critic algorithm is developed for voltage regulation through single and multi-hub…

Systems and Control · Electrical Eng. & Systems 2026-03-10 Jingbo Wang , Roshni Anna Jacob , Harshal D. Kaushik , Jie Zhang

Type 1 diabetes is a serious disease in which individuals are unable to regulate their blood glucose levels, leading to various medical complications. Artificial pancreas (AP) systems have been developed as a solution for type 1 diabetic…

Signal Processing · Electrical Eng. & Systems 2023-05-18 Ke Ma , Hongkai Chen , Shan Lin

Objective: Anemia is a frequent comorbidity in hemodialysis patients that can be successfully treated by administering erythropoiesis-stimulating agents (ESAs). ESAs dosing is currently based on clinical protocols that often do not account…

Reinforcement Learning (RL) is a learning paradigm concerned with learning to control a system so as to maximize an objective over the long term. This approach to learning has received immense interest in recent times and success manifests…

Artificial Intelligence · Computer Science 2018-07-26 Sanyam Kapoor

This paper proposes a deep reinforcement learning (DRL)-based event-triggered controller design for networked artificial pancreas (AP) systems. Although existing DRL-based AP controllers typically assume periodic control updates, networked…

Systems and Control · Electrical Eng. & Systems 2026-05-18 Junya Ikemoto , Satoshi Maruyama , Kazumune Hashimoto

Preference-based reinforcement learning has gained prominence as a strategy for training agents in environments where the reward signal is difficult to specify or misaligned with human intent. However, its effectiveness is often limited by…

Machine Learning · Computer Science 2025-08-27 Jonathan Erskine , Taku Yamagata , Raúl Santos-Rodríguez

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

We systematically investigated a reinforcement learning (RL)-based closed-loop active flow control strategy to enhance the lift-to-drag ratio of a wing section with an NLF(1)-0115 airfoil at an angle of attack 5 degree. The effects of key…

Fluid Dynamics · Physics 2025-05-09 Qiong Liu , Luis Javier Trujillo Corona , Fangjun Shu , Andreas Gross

This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood…

Systems and Control · Electrical Eng. & Systems 2024-01-31 Beatrice Sonzogni , José María Manzano , Marco Polver , Fabio Previdi , Antonio Ferramosca

Diabetes cases worldwide have risen steadily over the past decades, lending urgency to the search for more efficient, effective, and personalized ways to treat the disease. Current treatment strategies, however, may fail to maintain…

Tissues and Organs · Quantitative Biology 2014-03-05 S. M. Kissler , C. Cichowitz , S. Sankaranarayanan , D. M. Bortz

Modelling pedestrian-driver interactions is critical for understanding human road user behaviour and developing safe autonomous vehicle systems. Existing approaches often rely on rule-based logic, game-theoretic models, or 'black-box'…

Artificial Intelligence · Computer Science 2025-11-03 Yueyang Wang , Mehmet Dogar , Gustav Markkula

To avoid myopic behavior, multi-step lookahead Bayesian optimization (BO) algorithms consider the sequential nature of BO and have demonstrated promising results in recent years. However, owing to the curse of dimensionality, most of these…

Machine Learning · Computer Science 2026-04-24 Mujin Cheon , Jay H. Lee , Dong-Yeun Koh , Calvin Tsay

Bus bunching remains a challenge for urban transit due to stochastic traffic and passenger demand. Traditional solutions rely on multi-agent reinforcement learning (MARL) in loop-line settings, which overlook realistic operations…

Artificial Intelligence · Computer Science 2026-03-20 Yifan Zhang

Traditional AI-based healthcare systems often rely on single-modal data, limiting diagnostic accuracy due to incomplete information. However, recent advancements in foundation models show promising potential for enhancing diagnosis…

Artificial Intelligence · Computer Science 2025-03-24 Sihan Wang , Suiyang Jiang , Yibo Gao , Boming Wang , Shangqi Gao , Xiahai Zhuang

Modern software applications demand efficient and reliable testing methodologies to ensure robust user interface functionality. This paper introduces an autonomous reinforcement learning (RL) agent integrated within a Behavior-Driven…

Software Engineering · Computer Science 2026-02-10 Ali Hassaan Mughal