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Related papers: Basal-Bolus Advisor for Type 1 Diabetes (T1D) Pati…

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People with type 1 diabetes (T1D) lack the ability to produce the insulin their bodies need. As a result, they must continually make decisions about how much insulin to self-administer to adequately control their blood glucose levels.…

Machine Learning · Computer Science 2020-09-22 Ian Fox , Joyce Lee , Rodica Pop-Busui , Jenna Wiens

Type 1 Diabetes (T1D) management requires continuous adjustment of insulin and lifestyle behaviors to maintain blood glucose within a safe target range. Although automated insulin delivery (AID) systems have improved glycemic outcomes, many…

People with Type 1 diabetes (T1D) require regular exogenous infusion of insulin to maintain their blood glucose concentration in a therapeutically adequate target range. Although the artificial pancreas and continuous glucose monitoring…

Signal Processing · Electrical Eng. & Systems 2020-09-08 Taiyu Zhu , Kezhi Li , Pau Herrero , Pantelis Georgiou

Managing physiological variables within clinically safe target zones is a central challenge in healthcare, particularly for chronic conditions such as Type 1 Diabetes Mellitus (T1DM). Reinforcement learning (RL) offers promise for…

Machine Learning · Computer Science 2025-08-07 David H. Mguni , Jing Dong , Wanrong Yang , Ziquan Liu , Muhammad Salman Haleem , Baoxiang Wang

Self-monitoring of blood glucose (SMBG) and continuous glucose monitoring (CGM) are commonly used by type 1 diabetes (T1D) patients to measure glucose concentrations. The proposed adaptive basal-bolus algorithm (ABBA) supports inputs from…

Systems and Control · Electrical Eng. & Systems 2024-12-20 Qingnan Sun , Marko V. Jankovic , João Budzinski , Brett Moore , Peter Diem , Christoph Stettler , Stavroula G. Mougiakakou

The widespread adoption of effective hybrid closed loop systems would represent an important milestone of care for people living with type 1 diabetes (T1D). These devices typically utilise simple control algorithms to select the optimal…

Machine Learning · Computer Science 2023-05-08 Harry Emerson , Matthew Guy , Ryan McConville

The existing adaptive basal-bolus advisor (ABBA) was further developed to benefit patients under insulin therapy with multiple daily injections (MDI). Three different in silico experiments were conducted with the DMMS.R simulator to…

Tissues and Organs · Quantitative Biology 2019-06-21 Qingnan Sun , Marko V. Jankovic , Stavroula G. Mougiakakou

Patients with diabetes who are self-monitoring have to decide right before each meal how much insulin they should take. A standard bolus advisor exists, but has never actually been proven to be optimal in any sense. We challenged this rule…

Machine Learning · Statistics 2020-07-24 Frédéric Logé , Erwan Le Pennec , Habiboulaye Amadou-Boubacar

People with type 1 diabetes (T1D) struggle to calculate the optimal insulin dose at mealtime, especially when under multiple daily injections (MDI) therapy. Effectively, they will not always perform rigorous and precise calculations, but…

Artificial Intelligence · Computer Science 2023-09-19 Anas El Fathi , Marc D. Breton

In this paper we investigate the use of model-based reinforcement learning to assist people with Type 1 Diabetes with insulin dose decisions. The proposed architecture consists of multiple Echo State Networks to predict blood glucose levels…

Despite recent advances in insulin preparations and technology, adjusting insulin remains an ongoing challenge for the majority of people with type 1 diabetes (T1D) and longstanding type 2 diabetes (T2D). In this study, we propose the…

Blood Glucose (BG) control involves keeping an individual's BG within a healthy range through extracorporeal insulin injections is an important task for people with type 1 diabetes. However,traditional patient self-management is cumbersome…

Artificial Intelligence · Computer Science 2024-03-18 Weiwei Gu , Senquan Wang

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

We propose a dual-hormone delivery strategy by exploiting deep reinforcement learning (RL) for people with Type 1 Diabetes (T1D). Specifically, double dilated recurrent neural networks (RNN) are used to learn the hormone delivery strategy,…

Quantitative Methods · Quantitative Biology 2019-10-10 Taiyu Zhu , Kezhi Li , Pantelis Georgiou

Automated insulin delivery for Type 1 Diabetes must balance glucose control and safety under uncertain meals and physiological variability. While reinforcement learning (RL) enables adaptive personalization, existing approaches struggle to…

Machine Learning · Computer Science 2026-01-23 Yushen Liu , Yanfu Zhang , Xugui Zhou

Calculating mealtime insulin doses poses a significant challenge for individuals with Type 1 Diabetes (T1D). Doses should perfectly compensate for expected post-meal glucose excursions, requiring a profound understanding of the individual's…

Quantitative Methods · Quantitative Biology 2024-06-24 Anas El Fathi , Elliott Pryor , Marc D. Breton

Type I Diabetes (T1D) is a chronic disease in which the body's ability to synthesize insulin is destroyed. It can be difficult for patients to manage their T1D, as they must control a variety of behavioral factors that affect glycemic…

Logic in Computer Science · Computer Science 2019-06-25 Josephine Lamp , Simone Silvetti , Marc Breton , Laura Nenzi , Lu Feng

Regular physical activity is known to be beneficial to people suffering from diabetes type 2. Nevertheless, most such people are sedentary. Smartphones create new possibilities for helping people to adhere to their physical activity goals,…

Computers and Society · Computer Science 2018-05-16 Irit Hochberg , Guy Feraru , Mark Kozdoba , Shie Mannor , Moshe Tennenholtz , Elad Yom-Tov

This paper proposes a robust control design method using reinforcement-learning for controlling partially-unknown dynamical systems under uncertain conditions. The method extends the optimal reinforcement-learning algorithm with a new…

Systems and Control · Electrical Eng. & Systems 2020-04-17 Phuong D. Ngo , Fred Godtliebsen

Type 1 diabetes mellitus (T1D) is characterized by insulin deficiency and blood glucose (BG) control issues. The state-of-the-art solution for continuous BG control is reinforcement learning (RL), where an agent can dynamically adjust…

Machine Learning · Computer Science 2026-01-26 Jingchi Jiang , Rujia Shen , Boran Wang , Yi Guan
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