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A method for automatically finding a program (bytecode) realizing the given algorithm is developed. The algorithm is specified as a set of tests (input\_data) $ \rightarrow $ (output\_data). Genetic methods made it possible to find the…

Neural and Evolutionary Computing · Computer Science 2018-07-18 S. I. Khashin , S. E. Vaganov

Locating the promoter region in DNA sequences is of paramount importance in the field of bioinformatics. This is a problem widely studied in the literature, however, not yet fully resolved. Some researchers have presented remarkable results…

Machine Learning · Computer Science 2021-12-08 Lauro Moraes , Pedro Silva , Eduardo Luz , Gladston Moreira

Procrustes problems are matrix approximation problems searching for a~transformation of the given dataset to fit another dataset. They find applications in numerous areas, such as factor and multivariate analysis, computer vision,…

Optimization and Control · Mathematics 2023-05-01 Terézia Fulová , Mária Trnovská

Accumulation of standardized data collections is opening up novel opportunities for holistic characterization of genome function. The limited scalability of current preprocessing techniques has, however, formed a bottleneck for full…

Quantitative Methods · Quantitative Biology 2013-04-09 Leo Lahti , Aurora Torrente , Laura L. Elo , Alvis Brazma , Johan Rung

Visual Programming has recently emerged as an alternative to end-to-end black-box visual reasoning models. This type of method leverages Large Language Models (LLMs) to generate the source code for an executable computer program that solves…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Jaywon Koo , Ziyan Yang , Paola Cascante-Bonilla , Baishakhi Ray , Vicente Ordonez

We present the data model, design choices, and performance of ProvSQL, a general and easy-to-deploy provenance tracking and probabilistic database system implemented as a PostgreSQL extension. ProvSQL's data and query models closely reflect…

Databases · Computer Science 2025-12-18 Aryak Sen , Silviu Maniu , Pierre Senellart

Recent developments in next generation sequencing technology have led to the creation of extensive, open-source protein databases consisting of hundreds of millions of sequences. To render these sequences applicable in biomedical…

Machine Learning · Computer Science 2024-12-10 Azwad Tamir , Jiann-Shiun Yuan

Metagenomics enables the reconstruction of microbial genomes in complex microbial communities without the need for culturing. Since assembly typically results in fragmented genomes the grouping of genome fragments (contigs) belonging to the…

Genome sequence analysis, which examines the DNA sequences of organisms, drives advances in many critical medical and biotechnological fields. Given its importance and the exponentially growing volumes of genomic sequence data, there are…

In large-scale industrial LLM systems, prompt templates often expand to thousands of tokens as teams iteratively incorporate sections such as task instructions, few-shot examples, and heuristic rules to enhance robustness and coverage. This…

Computation and Language · Computer Science 2025-10-09 Zhentao Xu , Fengyi Li , Albert Chen , Xiaofeng Wang

Genomic data sets are growing dramatically as the cost of sequencing continues to decline and small sequencing devices become available. Enormous community databases store and share this data with the research community, but some of these…

We present AngstromPro, a versatile, modular and open-source software built on Python for managing, visualizing and analyzing large datasets acquired via Scanning Tunneling Microscopes (STM). Its robust architecture features a top-level…

Superconductivity · Physics 2026-04-22 Huiyu Zhao , Jiahao Yan , Catherine Dawson , Haitao Yang , Hong-Jun Gao

For nearly 50 years microbiologists have been determining prokaryotic genome relatedness by means of nucleic acid reassociation kinetics. These methods, however, are technically challenging, difficult to reproduce, and - given the time and…

Genomics · Quantitative Biology 2012-02-24 Paul A. Muller , Slava S. Epstein

Modeling sequence evolution on phylogenetic trees is a useful technique in computational biology. Especially powerful are models which take account of the heterogeneous nature of sequence evolution according to the "grammar" of the encoded…

Quantitative Methods · Quantitative Biology 2015-06-04 Oscar Westesson , Ian Holmes

Motivation: Quality control of genomic data is an essential but complicated multi-step procedure, often requiring separate installation and expert familiarity with a combination of disparate bioinformatics tools. Results: To provide an…

Genomics · Quantitative Biology 2021-05-06 Christina Vasilopoulou , Benjamin Wingfield , Andrew P. Morris , William Duddy

DNA sequencing, especially of microbial genomes and metagenomes, has been at the core of recent research advances in large-scale comparative genomics. The data deluge has resulted in exponential growth in genomic datasets over the past…

Nowadays, due to the increasing amount of experimental data obtained by sequencing, the most interest is focused on determining the functions and characteristics of its individual parts of the genome instead of determining the nucleotide…

Genomics · Quantitative Biology 2021-02-09 Marina Galchenkova , Aleksei Korzhenkov

In this paper a novel biclustering algorithm based on artificial intelligence (AI) is introduced. The method called EBIC aims to detect biologically meaningful, order-preserving patterns in complex data. The proposed algorithm is probably…

Machine Learning · Computer Science 2018-07-27 Patryk Orzechowski , Moshe Sipper , Xiuzhen Huang , Jason H. Moore

The multivariate probit is popular for modeling correlated binary data, with an attractive balance of flexibility and simplicity. However, considerable challenges remain in computation and in devising a clear statistical framework. Interest…

Methodology · Statistics 2020-04-22 Bryan W. Ting , Fred A. Wright , Yi-Hui Zhou

Prototypical networks aim to build intrinsically explainable models based on the linear summation of concepts. Concepts are coherent entities that we, as humans, can recognize and associate with a certain object or entity. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Hugues Turbé , Mina Bjelogrlic , Gianmarco Mengaldo , Christian Lovis