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Clustering is an essential data mining tool for analyzing and grouping similar objects. In big data applications, however, many clustering algorithms are infeasible due to their high memory requirements and/or unfavorable runtime…

Data Structures and Algorithms · Computer Science 2026-01-27 Gregor Ulm , Simon Smith , Adrian Nilsson , Emil Gustavsson , Mats Jirstrand

In recent years, stream processing has become a prominent approach for incrementally handling large amounts of data, with special support and libraries in many programming languages. Unfortunately, support in Prolog has so far been lacking…

Programming Languages · Computer Science 2019-09-20 Paul Tarau , Jan Wielemaker , Tom Schrijvers

Program classification can be regarded as a high-level abstraction of code, laying a foundation for various tasks related to source code comprehension, and has a very wide range of applications in the field of software engineering, such as…

Software Engineering · Computer Science 2022-05-03 Kesu Wang , Meng Yan , He Zhang , Haibo Hu

Protein language models (PLMs) face a fundamental divide: masked language models (MLMs) excel at fitness prediction while causal models enable generation, forcing practitioners to maintain separate architectures. We introduce…

Machine Learning · Computer Science 2026-02-03 Furkan Eris

A coreset is a subset of the training set, using which a machine learning algorithm obtains performances similar to what it would deliver if trained over the whole original data. Coreset discovery is an active and open line of research as…

Machine Learning · Computer Science 2020-02-21 Pietro Barbiero , Giovanni Squillero , Alberto Tonda

In this paper we present a novel tool to evaluate problem solving systems. Instead of using a system to solve a problem, we suggest using the problem to evaluate the system. By finding a numerical representation of a problem's complexity,…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Goren Gordon , Uri Einziger-Lowicz

Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often provide long lists of tens or hundreds of disease gene…

Quantitative Methods · Quantitative Biology 2011-06-03 Fantine Mordelet , Jean-Philippe Vert

Clustering is a difficult and widely-studied data mining task, with many varieties of clustering algorithms proposed in the literature. Nearly all algorithms use a similarity measure such as a distance metric (e.g. Euclidean distance) to…

Neural and Evolutionary Computing · Computer Science 2019-10-24 Andrew Lensen , Bing Xue , Mengjie Zhang

PHAST is a software package written in standard Fortran, with MPI and CUDA extensions, able to efficiently perform parallel multicanonical Monte Carlo simulations of single or multiple heteropolymeric chains, as coarse-grained models for…

Computational Physics · Physics 2017-02-08 Rafael B. Frigori

To facilitate flexible and efficient structural bioinformatics analyses, new functionality for three-dimensional structure processing and analysis has been introduced into PyCogent -- a popular feature-rich framework for sequence-based…

Biomolecules · Quantitative Biology 2018-10-01 Marcin Cieslik , Zygmunt Derewenda , Cameron Mura

Complex-valued sparse coding is a data representation which employs a dictionary of two-dimensional subspaces, while imposing a sparse, factorial prior on complex amplitudes. When trained on a dataset of natural image patches, it learns…

Machine Learning · Computer Science 2014-02-19 Wiktor Mlynarski

For decades, researchers have been applying computer simulation to address problems in biology. However, many of these "grand challenges" in computational biology, such as simulating how proteins fold, remained unsolved due to their great…

Biological Physics · Physics 2009-01-08 Stefan M. Larson , Christopher D. Snow , Michael Shirts , Vijay S. Pande

Various general-purpose distributed systems have been proposed to cope with high-diversity applications in the pipeline of Big Data analytics. Most of them provide simple yet effective primitives to simplify distributed programming. While…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-13 Yijie Mei , Yanyan Shen , Yanmin Zhu , Linpeng Huang

Technical signs of progress during the last decades has led to a situation in which the accumulation of genome sequence data is increasingly fast and cheap. The huge amount of molecular data available nowadays can help addressing new and…

Genomics · Quantitative Biology 2017-05-02 Christophe Guyeux , Bashar Al-Nuaimi , Bassam AlKindy , Jean-François Couchot , Michel Salomon

This paper presents a novel approach, called Prototype-based Self-Distillation (ProS), for unsupervised face representation learning. The existing supervised methods heavily rely on a large amount of annotated training facial data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-11-08 Xing Di , Yiyu Zheng , Xiaoming Liu , Yu Cheng

In order to achieve competitive performance, abstract machines for Prolog and related languages end up being large and intricate, and incorporate sophisticated optimizations, both at the design and at the implementation levels. At the same…

Programming Languages · Computer Science 2020-02-19 Jose F. Morales , Manuel Carro , Manuel Hermenegildo

We propose a low-computational strategy for the efficient implementation of the "atom selection step" in sparse representation algorithms. The proposed procedure is based on simple tests enabling to identify subsets of atoms which cannot be…

Signal Processing · Electrical Eng. & Systems 2018-12-06 Clément Dorffer , Angélique Drémeau , Cedric Herzet

Motivation: The availability of thousands of invidual genomes of one species should boost rapid progress in personalized medicine or understanding of the interaction between genotype and phenotype, to name a few applications. A key…

Computational Engineering, Finance, and Science · Computer Science 2017-03-03 Agnieszka Danek , Sebastian Deorowicz , Szymon Grabowski

We present new algorithms and fast implementations to find efficient approximations for modelling stochastic processes. For many numerical computations it is essential to develop finite approximations for stochastic processes. While the…

Optimization and Control · Mathematics 2020-12-03 Kipngeno Benard Kirui , Georg Ch. Pflug , Alois Pichler

Compact Genetic Algorithms (cGAs) are condensed variants of classical Genetic Algorithms (GAs) that use a probability vector representation of the population instead of the complete population. cGAs have been shown to significantly reduce…

Neural and Evolutionary Computing · Computer Science 2025-04-07 Prasanta Dutta , Anirban Mukhopadhyay
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