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In the era of information explosion, spatio-temporal data mining serves as a critical part of urban management. Considering the various fields demanding attention, e.g., traffic state, human activity, and social event, predicting multiple…

Artificial Intelligence · Computer Science 2023-09-19 Zijian Zhang , Xiangyu Zhao , Qidong Liu , Chunxu Zhang , Qian Ma , Wanyu Wang , Hongwei Zhao , Yiqi Wang , Zitao Liu

Prokaryotic gene prediction plays an important role in understanding the biology of organisms and their function with applications in medicine and biotechnology. Although the current gene finders are highly sensitive in finding long genes,…

Genomics · Quantitative Biology 2023-07-21 Tony Tu , Gautham Krishna , Amirali Aghazadeh

Genome-resolved metagenomics has contributed largely to discovering prokaryotic genomes. When applied to microscopic eukaryotes, challenges such as the high number of introns and repeat regions found in nuclear genomes have hampered the…

Genomics · Quantitative Biology 2025-10-14 Yuhao Tong , Vanessa Rossetto Marcelino , Robert Turnbull , Heroen Verbruggen

Read mapping is a fundamental, yet computationally-expensive step in many genomics applications. It is used to identify potential matches and differences between fragments (called reads) of a sequenced genome and an already known genome…

The Binary Search Tree (BST) is average in computer science which supports a compact data structure in memory and oneself even conducts a row of quick algorithms, by which people often apply it in dynamical circumstance. Besides these…

Data Structures and Algorithms · Computer Science 2018-10-05 Yong Tan

Language model approaches have recently been integrated into binary analysis tasks, such as function similarity detection and function signature recovery. These models typically employ a two-stage training process: pre-training via Masked…

Software Engineering · Computer Science 2024-12-24 Hanxiao Lu , Hongyu Cai , Yiming Liang , Antonio Bianchi , Z. Berkay Celik

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

The fall of prices of the high-throughput genome sequencing changes the landscape of modern genomics. A number of large scale projects aimed at sequencing many human genomes are in progress. Genome sequencing also becomes an important aid…

Data Structures and Algorithms · Computer Science 2017-03-03 Sebastian Deorowicz , Agnieszka Danek , Marcin Niemiec

Understanding the dynamic nature of protein structures is essential for comprehending their biological functions. While significant progress has been made in predicting static folded structures, modeling protein motions on microsecond to…

In this paper, we study an under-explored but important factor of diffusion generative models, i.e., the combinatorial complexity. Data samples are generally high-dimensional, and for various structured generation tasks, additional…

Machine Learning · Computer Science 2026-04-30 Rui Xu , Jiepeng Wang , Hao Pan , Yang Liu , Xin Tong , Shiqing Xin , Changhe Tu , Taku Komura , Wenping Wang

Personalizing generative models offers a way to guide image generation with user-provided references. Current personalization methods can invert an object or concept into the textual conditioning space and compose new natural sentences for…

Detecting variation in the evolutionary process along chromosomes is increasingly important as whole-genome data becomes more widely available. For example, factors such as incomplete lineage sorting, horizontal gene transfer, and…

Populations and Evolution · Quantitative Biology 2017-01-03 Elizabeth S. Allman , Laura S. Kubatko , John A. Rhodes

ProSper is a python library containing probabilistic algorithms to learn dictionaries. Given a set of data points, the implemented algorithms seek to learn the elementary components that have generated the data. The library widens the scope…

Signal Processing · Electrical Eng. & Systems 2019-08-20 Georgios Exarchakis , Jörg Bornschein , Abdul-Saboor Sheikh , Zhenwen Dai , Marc Henniges , Jakob Drefs , Jörg Lücke

Scanning transmission electron microscopy (STEM) is an extremely versatile method for studying materials on the atomic scale. Many STEM experiments are supported or validated with electron scattering simulations. However, using the…

The labelling of speech corpora is a laborious and time-consuming process. The ProsoBeast Annotation Tool seeks to ease and accelerate this process by providing an interactive 2D representation of the prosodic landscape of the data, in…

Audio and Speech Processing · Electrical Eng. & Systems 2021-06-16 Branislav Gerazov , Michael Wagner

Memory profiling captures programs' dynamic memory behavior, assisting programmers in debugging, tuning, and enabling advanced compiler optimizations like speculation-based automatic parallelization. As each use case demands its unique…

Performance · Computer Science 2023-11-07 Ziyang Xu , Yebin Chon , Yian Su , Zujun Tan , Sotiris Apostolakis , Simone Campanoni , David I. August

Important graph mining problems such as Clustering are computationally demanding. To significantly accelerate these problems, we propose ProbGraph: a graph representation that enables simple and fast approximate parallel graph mining with…

This paper introduces provGen, a generator aimed at producing large synthetic provenance graphs with predictable properties and of arbitrary size. Synthetic provenance graphs serve two main purposes. Firstly, they provide a variety of…

Databases · Computer Science 2014-06-11 Hugo Firth , Paolo Missier

Provenance management must be present to enhance the overall security and reliability of long-tail microscopy (LTM) data management systems. However, there are challenges in provenance for domains with LTM data. The provenance data need to…

Cryptography and Security · Computer Science 2021-09-23 Hessam Moeini , Todd Nicholson , Klara Nahrstedt , Gianni Pezzarossi

Background: High-throughput proteomics techniques, such as mass spectrometry (MS)-based approaches, produce very high-dimensional data-sets. In a clinical setting one is often interested in how mass spectra differ between patients of…