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Purpose: To develop and validate a multi-parametric SAturation-recovery single-SHot Acquisition (mSASHA) cardiac T1 and T2 mapping technique with high accuracy and precision in a single breath-hold. Methods: The mSASHA acquisition consists…

Purpose: To implement and evaluate a new dictionary-based technique for native myocardial T1 and T2 mapping using Cartesian sampling. Methods: The proposed technique (Multimapping) consisted of single-shot Cartesian image acquisitions in 10…

Medical Physics · Physics 2022-01-05 Markus Henningsson

Purpose: To develop and evaluate MyoMapNet, a rapid myocardial T1 mapping approach that uses neural networks (NN) to estimate voxel-wise myocardial T1 and extracellular (ECV) from T1-weighted images collected after a single inversion pulse…

Medical Physics · Physics 2021-04-02 Hossam El-Rewaidy , Rui Guo , Amanda Paskavitz , Tuyen Yankama , Long Ngo , Bjoern Menze , Reza Nezafat

Background: Accurate myocardial T1 mapping at 5T remains a technical challenge due to field inhomogeneity and prolonged T1 values. The aim of this study is to develop an accurate and clinically applicable myocardial T1 mapping technique for…

Myocardial pathology segmentation (MyoPS) is critical for the risk stratification and treatment planning of myocardial infarction (MI). Multi-sequence cardiac magnetic resonance (MS-CMR) images can provide valuable information. For…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Wangbin Ding , Lei Li , Junyi Qiu , Sihan Wang , Liqin Huang , Yinyin Chen , Shan Yang , Xiahai Zhuang

Cardiac T1 mapping is a valuable quantitative MRI technique for diagnosing diffuse myocardial diseases. Traditional methods, relying on breath-hold sequences and cardiac triggering based on an ECG signal, face challenges with patient…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Eyal Hanania , Adi Zehavi-Lenz , Ilya Volovik , Daphna Link-Sourani , Israel Cohen , Moti Freiman

Myocardial motion and deformation are rich descriptors that characterize cardiac function. Image registration, as the most commonly used technique for myocardial motion tracking, is an ill-posed inverse problem which often requires prior…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Chen Qin , Shuo Wang , Chen Chen , Wenjia Bai , Daniel Rueckert

Purpose: To develop a free-breathing myocardial T1 mapping technique using inversion-recovery (IR) radial fast low-angle shot (FLASH) and calibrationless motion-resolved model-based reconstruction. Methods: Free-running (free-breathing,…

Purpose: To develop a cardiac T1 mapping method for free-breathing 3D T1 mapping of the whole heart at 3T with transmit B1 (B1+) correction Methods: A free-breathing, ECG-gated inversion recovery sequence with spoiled gradient-echo readout…

Medical Physics · Physics 2021-11-16 Paul Kyu Han , Thibault Marin , Yanis Djebra , Vanessa Landes , Yue Zhuo , Georges El Fakhri , Chao Ma

Myocardial pathology segmentation (MyoPS) can be a prerequisite for the accurate diagnosis and treatment planning of myocardial infarction. However, achieving this segmentation is challenging, mainly due to the inadequate and indistinct…

Image and Video Processing · Electrical Eng. & Systems 2022-11-30 Junyi Qiu , Lei Li , Sihan Wang , Ke Zhang , Yinyin Chen , Shan Yang , Xiahai Zhuang

Computational fluid dynamics (CFD) can be used for evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Tina Yao , Endrit Pajaziti , Michael Quail , Silvia Schievano , Jennifer A Steeden , Vivek Muthurangu

In this paper, we propose an enhanced 3D myocardial strain estimation procedure, which combines complementary displacement information from multiple orientations of a single imaging modality (untagged CMR SSFP images). To estimate…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Mohamed Abdelkhalek , Heba Aguib , Mohamed Moustafa , Khalil Elkhodary

Myocardial T1 mapping is a cardiac MRI technique, used to assess myocardial fibrosis. In this technique, a series of T1-weighted MRI images are acquired with different saturation or inversion times. These images are fitted to the T1 model…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Dar Arava , Mohammad Masarwy , Samah Khawaled , Moti Freiman

Animal cells use traction forces to sense the mechanics and geometry of their environment. Measuring these traction forces requires a workflow combining cell experiments, image processing and force reconstruction based on elasticity theory.…

Quantitative Methods · Quantitative Biology 2016-08-24 Jerome R. Soine , Nils Hersch , Georg Dreissen , Nico Hampe , Bernd Hoffmann , Rudolf Merkel , Ulrich S. Schwarz

Assessment of myocardial viability is essential in diagnosis and treatment management of patients suffering from myocardial infarction, and classification of pathology on myocardium is the key to this assessment. This work defines a new…

Magnetic resonance (MR) protocols rely on several sequences to assess pathology and organ status properly. Despite advances in image analysis, we tend to treat each sequence, here termed modality, in isolation. Taking advantage of the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-11 Agisilaos Chartsias , Giorgos Papanastasiou , Chengjia Wang , Scott Semple , David E. Newby , Rohan Dharmakumar , Sotirios A. Tsaftaris

Patient motion is well-known for degrading image quality during medical imaging. Especially positron emission tomography (PET) is susceptible to motion due to its usually long scan times. In hybrid PET/MRI (magnetic resonance imaging),…

Medical Physics · Physics 2019-05-21 Lynn Johann Frohwein , Florian Büther , Klaus Peter Schäfers

Brightfield time-lapse imaging is widely used in cardiac tissue engineering, yet the absence of standardized, interpretable analytical frameworks limits reproducibility and cross-platform comparison. We present an open, scalable…

Quantitative Methods · Quantitative Biology 2026-04-10 Hiba Kobeissi , Samuel J. DePalma , Javiera Jilberto , David Nordsletten , Brendon M. Baker , Emma Lejeune

Objective: To develop an accurate myocardial T1 mapping technique at 5T using Look-Locker-based multiple inversion-recovery with the real-time spoiled gradient echo (GRE) acquisition. Approach: The proposed T1 mapping technique (mIR-rt)…

Medical Physics · Physics 2025-08-29 Linqi Ge , Yihang Zhang , Huibin Zhu , Lang Zhang , Yihang Zhou , Haifeng Wang , Dong Liang , Hairong Zheng , Yanjie Zhu

In cardiac Magnetic Resonance Imaging (MRI) analysis, simultaneous myocardial segmentation and T2 quantification are crucial for assessing myocardial pathologies. Existing methods often address these tasks separately, limiting their…

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