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Early detection of cardiac dysfunction through routine screening is vital for diagnosing cardiovascular diseases. An important metric of cardiac function is the left ventricular ejection fraction (EF), where lower EF is associated with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Ece Ozkan , Thomas M. Sutter , Yurong Hu , Sebastian Balzer , Julia E. Vogt

T1 mapping is a quantitative magnetic resonance imaging (qMRI) technique that has emerged as a valuable tool in the diagnosis of diffuse myocardial diseases. However, prevailing approaches have relied heavily on breath-hold sequences to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Eyal Hanania , Ilya Volovik , Lilach Barkat , Israel Cohen , Moti Freiman

Myocardial motion tracking stands as an essential clinical tool in the prevention and detection of cardiovascular diseases (CVDs), the foremost cause of death globally. However, current techniques suffer from incomplete and inaccurate…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Chengkang Shen , Hao Zhu , You Zhou , Yu Liu , Si Yi , Lili Dong , Weipeng Zhao , David J. Brady , Xun Cao , Zhan Ma , Yi Lin

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

Computer Vision and Pattern Recognition · Computer Science 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

In silico tissue models enable evaluating quantitative models of magnetic resonance imaging. This includes validating and sensitivity analysis of imaging biomarkers and tissue microstructure parameters. We propose a novel method to generate…

The Magnetic Resonance Fingerprinting (MRF) approach aims to estimate multiple MR or physiological parameters simultaneously with a single fast acquisition sequence. Most of the MRF studies proposed so far have used simple MR sequence types…

Neurons and Cognition · Quantitative Biology 2024-07-16 Antoine Barrier , Thomas Coudert , Aurélien Delphin , Benjamin Lemasson , Thomas Christen

Purpose: Advancements in MRI Tissue Phase Velocity Mapping (TPM) allow for the acquisition of higher quality velocity cardiac images providing better assessment of regional myocardial deformation for accurate disease diagnosis,…

Medical Physics · Physics 2018-08-21 Christina Koutsoumpa , Jennifer Keegan , David Firmin , Guang-Zhong Yang , Duncan Gillies

Purpose: To develop a new sequence, MIMOSA, for highly-efficient T1, T2, T2*, proton density (PD), and source separation quantitative susceptibility mapping (QSM). Methods: MIMOSA was developed based on 3D-quantification using an…

Myocardial point tracking (MPT) has recently emerged as a promising direction for motion estimation in echocardiography, driven by advances in general-purpose point tracking methods. However, myocardial motion fundamentally differs from…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Md Abulkalam Azad , Vegard Holmstrøm , John Nyberg , Lasse Lovstakken , Håvard Dalen , Bjørnar Grenne , Andreas Østvik

Cardiac amyloidosis, a rare and highly morbid condition, presents significant challenges for detection through echocardiography. Recently, there has been a surge in proposing machine-learning algorithms to identify cardiac amyloidosis, with…

Image and Video Processing · Electrical Eng. & Systems 2024-06-10 Zishun Feng , Joseph A. Sivak , Ashok K. Krishnamurthy

Objective: We aim to provide an algorithm for the detection of myocardial infarction that operates directly on ECG data without any preprocessing and to investigate its decision criteria. Approach: We train an ensemble of fully…

Computers and Society · Computer Science 2019-02-06 Nils Strodthoff , Claas Strodthoff

Electrocardiogram (ECG) is an authoritative source to diagnose and counter critical cardiovascular syndromes such as arrhythmia and myocardial infarction (MI). Current machine learning techniques either depend on manually extracted features…

Machine Learning · Computer Science 2021-07-22 Zeeshan Ahmad , Anika Tabassum , Ling Guan , Naimul Khan

Elucidating the biomechanical behavior of the myocardium is crucial for understanding cardiac physiology, but cannot be directly inferred from clinical imaging and typically requires finite element (FE) simulations. However, conventional FE…

Medical Physics · Physics 2025-06-27 Siyu Mu , Wei Xuan Chan , Choon Hwai Yap

Myocardial motion tracking is important for assessing cardiac function and diagnosing cardiovascular diseases, for which cine cardiac magnetic resonance (CMR) has been established as the gold standard imaging modality. Many existing methods…

Image and Video Processing · Electrical Eng. & Systems 2025-07-24 Jiahui Yin , Xinxing Cheng , Jinming Duan , Yan Pang , Declan O'Regan , Hadrien Reynaud , Qingjie Meng

Myocardial Contrast Echocardiography (MCE) with micro-bubble contrast agent enables myocardial perfusion quantification which is invaluable for the early detection of coronary artery diseases. In this paper, we proposed a new segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Yuanwei Li , Chin Pang Ho , Navtej Chahal , Roxy Senior , Meng-Xing Tang

Advancing human induced pluripotent stem cell derived cardiomyocyte (hiPSC-CM) technology will lead to significant progress ranging from disease modeling, to drug discovery, to regenerative tissue engineering. Yet, alongside these potential…

PURPOSE To develop free-running multi-echo GRE for cardiac- and respiratory-motion-resolved whole-heart fat fraction quantification. METHODS Multi-echo readouts optimized for water-fat separation and quantification were integrated within a…

Recovering the 3D motion of the heart from cine cardiac magnetic resonance (CMR) imaging enables the assessment of regional myocardial function and is important for understanding and analyzing cardiovascular disease. However, 3D cardiac…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Qingjie Meng , Chen Qin , Wenjia Bai , Tianrui Liu , Antonio de Marvao , Declan P O'Regan , Daniel Rueckert

We developed a new magnetic resonance imaging method called multinuclear fingerprinting (MNF) which leverages simultaneously-acquired proton (1H) and sodium (23Na) data to generate seven quantitative maps of the whole brain: proton density…

Medical Physics · Physics 2026-05-25 Gonzalo G. Rodriguez , Zidan Yu , Lauren O'Donnell , Martijn A. Cloos , Guillaume Madelin

Cardiac T1 mapping provides critical quantitative insights into myocardial tissue composition, enabling the assessment of pathologies such as fibrosis, inflammation, and edema. However, the inherently dynamic nature of the heart imposes…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Tamir Shor , Moti Freiman , Chaim Baskin , Alex Bronstein