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The "reproducibility crisis" has been a highly visible source of scientific controversy and dispute. Here, I propose and review several avenues for identifying and prioritizing research studies for the purpose of targeted validation. Of the…

Computers and Society · Computer Science 2018-04-24 Gopal P. Sarma

Replication of scientific experiments is critical to the advance of science. Unfortunately, the discipline of Computer Science has never treated replication seriously, even though computers are very good at doing the same thing over and…

General Literature · Computer Science 2013-04-15 Ian P. Gent

The rapid growth of scientific literature has made manual extraction of structured knowledge increasingly impractical. To address this challenge, we introduce SCILIRE, a system for creating datasets from scientific literature. SCILIRE has…

Computation and Language · Computer Science 2026-03-16 Necva Bölücü , Jessica Irons , Changhyun Lee , Brian Jin , Maciej Rybinski , Huichen Yang , Andreas Duenser , Stephen Wan

The FAIR principles for scientific data (Findable, Accessible, Interoperable, Reusable) are also relevant to other digital objects such as research software and scientific workflows that operate on scientific data. The FAIR principles can…

Digital Libraries · Computer Science 2022-12-16 Sean R. Wilkinson , Greg Eisenhauer , Anuj J. Kapadia , Kathryn Knight , Jeremy Logan , Patrick Widener , Matthew Wolf

A major challenge for niche scientific and technical domains in leveraging coding agents is the lack of access to up-to-date, domain- specific knowledge. Foundational models often demonstrate limited reasoning capabilities in specialized…

Artificial Intelligence · Computer Science 2026-04-22 Santosh Ganji

Scientific computing can in some sense be distilled to the execution of an application - or rather sets of applications which are combined into complex workflows. Due to the complexity and number both of scientific packages as well as…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-08-01 Bruce Becker , Sean Murray

In computational physics, chemistry, and biology, the implementation of new techniques in a shared and open source software lowers barriers to entry and promotes rapid scientific progress. However, effectively training new software users…

As LLMs make their way into many aspects of our lives, one place that warrants increased scrutiny with LLM usage is scientific research. Using LLMs for generating or analyzing data for research purposes is gaining popularity. But when such…

Human-Computer Interaction · Computer Science 2024-05-13 Chirag Shah

Computational scientists are facing a new era where the old ways of developing and reusing code have to be left behind and a few daring steps are to be made towards new horizons. The present work analyzes the needs that drive this change,…

Computational Engineering, Finance, and Science · Computer Science 2021-08-23 Zsolt I. Lázár , Jouke R. Heringa , Bazil Pârv , Simon W. de Leeuw

Despite much creative work on methods and tools, reproducibility -- the ability to repeat the computational steps used to obtain a research result -- remains elusive. One reason for these difficulties is that extant tools for capturing…

Software Engineering · Computer Science 2022-08-30 Ian Foster , Carl Kesselman

With the advent of deep learning, text generation language models have improved dramatically, with text at a similar level as human-written text. This can lead to rampant misinformation because content can now be created cheaply and…

Computation and Language · Computer Science 2023-01-24 Sai Gurrapu , Lifu Huang , Feras A. Batarseh

With recent increasing computational and data requirements of scientific applications, the use of large clustered systems as well as distributed resources is inevitable. Although executing large applications in these environments brings…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-06-30 Alexandru Costan , Florin Pop , Corina Stratan , Ciprian Dobre , Catalin Leordeanu , Valentin Cristea

Large language models (LLMs) for code have become indispensable in various domains, including code generation, reasoning tasks and agent systems. While open-access code LLMs are increasingly approaching the performance levels of proprietary…

We introduce CSLib, an open-source framework for proving computer-science-related theorems and writing formally verified code in the Lean proof assistant. CSLib aims to be for computer science what Lean's Mathlib is for mathematics. Mathlib…

Literature is the primary expression of scientific knowledge and an important source of research data. However, scientific knowledge expressed in narrative text documents is not inherently machine reusable. To facilitate knowledge reuse,…

Computational methods have reshaped the landscape of modern biology. While the biomedical community is increasingly dependent on computational tools, the mechanisms ensuring open data, open software, and reproducibility are variably…

Other Quantitative Biology · Quantitative Biology 2020-07-28 Jaqueline J. Brito , Jun Li , Jason H. Moore , Casey S. Greene , Nicole A. Nogoy , Lana X. Garmire , Serghei Mangul

The FAIR (Findable, Accessible, Interoperable, and Reusable) data principles [1] promote the interoperability of scientific data by encouraging the use of persistent identifiers, standardized vocabularies, and formal metadata structures.…

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

Reproducibility is a key requirement for scientific progress. It allows the reproduction of the works of others, and, as a consequence, to fully trust the reported claims and results. In this work, we argue that, by facilitating…

Information Retrieval · Computer Science 2021-02-02 Alejandro Bellogín , Alan Said