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The aim of this article is to introduce a reporting framework for reproducible, interactive research applied to Big Clinical Data, based on open source technologies. The framework is constituted by the following three axes: (i) data, (ii)…

NOMAD CAMELS (short: CAMELS) is a configurable, open-source measurement software that records fully self-describing experimental data. It has its origins in the field of experimental physics where a wide variety of measurement instruments…

Instrumentation and Detectors · Physics 2024-03-13 Alexander D. Fuchs , Johannes A. F. Lehmeyer , Heinz Junkes , Heiko B. Weber , Michael Krieger

PLUMED is an open-source software package that is widely used for analyzing and enhancing molecular dynamics simulations that works in conjunction with most available molecular dynamics softwares. While the computational cost of PLUMED…

Computational Physics · Physics 2025-11-05 Daniele Rapetti , Massimiliano Bonomi , Carlo Camilloni , Giovanni Bussi , Gareth A. Tribello

In order to operate in a regulated world, researchers need to ensure compliance with ever-evolving landscape of information security regulations and best practices. This work explains the concept of Controlled Unclassified Information (CUI)…

Computers and Society · Computer Science 2022-11-29 Baijian Yang , Carolyn Ellis , Preston Smith , Huyunting Huang

Data-driven scientific discovery requires the iterative integration of scientific domain knowledge, statistical expertise, and an understanding of data semantics to make nuanced analytical decisions, e.g., about which variables,…

Reproducibility is one of the core dimensions that concur to deliver Trustworthy Artificial Intelligence. Broadly speaking, reproducibility can be defined as the possibility to reproduce the same or a similar experiment or method, thereby…

Artificial Intelligence · Computer Science 2023-02-27 Riccardo Albertoni , Sara Colantonio , Piotr Skrzypczyński , Jerzy Stefanowski

The high incidence of irreproducible research has led to urgent appeals for transparency and equitable practices in open science. For the scientific disciplines that rely on computationally intensive analyses of large data sets, a granular…

Science has a data management problem, as well as a project management problem. While industrial-grade data science teams have embraced the agile mindset, and adopted or created all kind of tools to create reproducible workflows,…

Computers and Society · Computer Science 2022-07-05 Juan Julián Merelo-Guervós , Mario García-Valdez

As computational analysis becomes increasingly more complex in health research, transparent sharing of analytical code is vital for reproducibility and trust. This practical guide, aligned to open science practices, outlines actionable…

Computational experiments have become essential for scientific discovery, allowing researchers to test hypotheses, analyze complex datasets, and validate findings. However, as computational experiments grow in scale and complexity, ensuring…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-03 Eleni Adamidi , Panayiotis Deligiannis , Nikos Foutris , Thanasis Vergoulis

The emergence of "big data" offers unprecedented opportunities for not only accelerating scientific advances but also enabling new modes of discovery. Scientific progress in many disciplines is increasingly enabled by our ability to examine…

Computers and Society · Computer Science 2017-07-03 Vasant G. Honavar , Mark D. Hill , Katherine Yelick

Ensuring the reproducibility of scientific work is crucial as it allows the consistent verification of scientific claims and facilitates the advancement of knowledge by providing a reliable foundation for future research. However,…

Software Engineering · Computer Science 2025-04-14 Lázaro Costa , Susana Barbosa , Jácome Cunha

The drive for reproducibility in the computational sciences has provoked discussion and effort across a broad range of perspectives: technological, legislative/policy, education, and publishing. Discussion on these topics is not new, but…

Quantitative Methods · Quantitative Biology 2018-10-10 Daniel G. Hurley , Joseph Cursons , Matthew Faria , David M. Budden , Vijay Rajagopal , Edmund J. Crampin

Crowdsourcing is a multidisciplinary research area including disciplines like artificial intelligence, human-computer interaction, database, and social science. To facilitate cooperation across disciplines, reproducibility is a crucial…

Databases · Computer Science 2016-09-06 Ruochen Jiang , Jiannan Wang

Open-source scientific software is effectively closed to modification by its complexity. With recent advances in technology, an agentic AI team led by a single human can now rapidly and robustly modify large codebases and re-open science to…

Software Engineering · Computer Science 2025-12-16 Ling-Hong Hung , Ka Yee Yeung

Collaborative data collection initiatives are increasingly becoming pivotal to cultural institutions and scholars, to boost the population of born-digital archives. For over a decade, organisations have been leveraging Semantic Web…

Digital Libraries · Computer Science 2022-06-17 Marilena Daquino , Mari Wigham , Enrico Daga , Lucia Giagnolini , Francesca Tomasi

Critical goals of scientific computing are to increase scientific rigor, reproducibility, and transparency while keeping up with ever-increasing computational demands. This work presents an integrated framework well-suited for data…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-13 Paul Nuyujukian

Computational Workflows are widely used in data analysis, enabling innovation and decision-making. In many domains (bioinformatics, image analysis, & radio astronomy) the analysis components are numerous and written in multiple different…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-24 Michael R. Crusoe , Sanne Abeln , Alexandru Iosup , Peter Amstutz , John Chilton , Nebojša Tijanić , Hervé Ménager , Stian Soiland-Reyes , Bogdan Gavrilovic , Carole Goble