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Magnetron sputtering is an essential technique in combinatorial materials science, enabling the efficient synthesis of thin-film materials libraries with continuous compositional gradients. For exploring multidimensional search spaces,…

Materials Science · Physics 2024-11-22 Felix Thelen , Rico Zehl , Jan Lukas Bürgel , Diederik Depla , Alfred Ludwig

In computed tomography (CT) reconstruction, scattering causes server quality degradation of the reconstructed CT images by introducing streaks and cupping artifacts which reduce the detectability of low contrast objects. Monte Carlo (MC)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Ammar Alsaffar , Steffen Kieß , Kaicong Sun , Sven Simon

Modern precision experiments trapping low-energy particles require detailed simulations of particle trajectories and spin precession to determine systematic measurement limitations and apparatus deficiencies. We developed PENTrack, a tool…

Instrumentation and Detectors · Physics 2017-05-24 Wolfgang Schreyer , Tatsuya Kikawa , Martin J. Losekamm , Stephan Paul , Rüdiger Picker

Depth-of-interaction (DOI) encoding is an effective strategy for reducing parallax error and preserving spatial resolution in positron emission tomography (PET), particularly in compact small-animal scanners. To enable efficient…

Medical Physics · Physics 2026-03-10 Satzhan Sitmukhambetov , Junwei Du , Mingwu Jin , Yujie Chi

PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve…

Instrumentation and Detectors · Physics 2015-03-19 A. Miceli , P. Amaudruz , F. Benard , D. A. Bryman , L. Kurchaninov , J. P. Martin , A. Muennich , F. Retiere , T. J. Ruth , V. Sossi , A. J. Stoessl

Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs

We propose a novel fast track finding system capable of reconstructing four dimensional particle trajectories in real time using precise space and time information of the hits. Recent developments in silicon pixel detectors achieved 150 ps…

Instrumentation and Detectors · Physics 2015-12-31 Nicola Neri , Marco Petruzzo

For dose calculations in ion beam therapy, it is vital to accurately determine the relative stopping power (RSP) distribution within the treated volume. Currently, RSP values are extrapolated from Hounsfield units (HU), measured with x-ray…

Organ-specific, targeted Field-of-View (FoV) Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) inserts are viable solutions for a number of imaging tasks where whole-body PET/MRI systems lack the necessary sensitivity and…

Instrumentation and Detectors · Physics 2019-09-19 J. M. C. Brown , S. E. Brunner , D. R. Schaart

This work explores the combination of liquid xenon as a scintillating medium and silicon photomultipliers as a readout in Positron Emission Tomography (PET) for enhanced Time-Of-Flight resolution. We present the results of our first…

Plastic scintillators are widely used as particle detectors in many fields, mainly, medicine, particle physics and astrophysics. Traditionally, they are coupled to a photo-multplier (PMT) but now silicon photo-multipliers (SiPM) are…

Instrumentation and Methods for Astrophysics · Physics 2018-09-28 G. Ros , G. Sáez-Cano , G. A. Medina-Tanco , A. D. Supanitsky

We have recently introduced the idea of making use of three-photon positron annihilations in positron emission tomography. In this paper the basic characteristics of the three-gamma imaging in PET are studied by means of Monte Carlo…

Medical Physics · Physics 2009-11-11 Krzysztof Kacperski , Nicholas M. Spyrou

Monte Carlo simulation plays an important role in the study of time of flight (TOF) positron emission tomography (PET) prototype. As it can incorporate accurate physical modeling of scintillation detection process, from scintillation light…

Instrumentation and Detectors · Physics 2013-09-17 Ze Chen , Zheng-Guo Hu , Jin-Da Chen , Xiu-Ling Zhang , Zhi-Yu Sun , Wen-Xue Huang , Jian-Song Wang , Zhong-Yan Guo , Guo-Qing Xiao

Nowadays, in Positron Emission Tomography (PET) systems, a Time of Flight information is used to improve the image reconstruction process. In Time of Flight PET (TOF-PET), fast detectors are able to measure the difference in the arrival…

Positron Emission Tomography (PET) is a crucial tool in medical imaging, particularly for diagnosing diseases like cancer and Alzheimer's. The advent of Positronium Lifetime Imaging (PLI) has opened new avenues for assessing the tissue…

Medical Physics · Physics 2024-03-25 Zhuo Chen , Chien-Min Kao , Hsin-Hsiung Huang , Lingling An

Research conducted in the framework of the J-PET project aims to develop a cost-effective total-body positron emission tomography scanner. As a first step on the way to construct a full-scale J-PET tomograph from long strips of plastic…

In the context of particle therapy monitoring, we are developing a gamma-ray detector to determine the ion range in vivo from the measurement of particle time-of-flight. For this application, a beam monitor capable to tag in time the…

Positron Annihilation Lifetime Spectroscopy (PALS) has shown to be a powerful tool to study the nanostructures of porous materials. Positron Emissions Tomography (PET) are devices allowing imaging of metabolic processes e.g. in human…

In the last years, high-resolution time tagging has emerged as the tool to tackle the problem of high-track density in the detectors of the next generation of experiments at particle colliders. Time resolutions below 50ps and event average…

Time-Of-Flight (TOF) is a noble technique that is used in Positron Emission Tomography (PET) imaging worldwide. The scintillator based imaging system that is being used around the world for TOF-PET is very expensive. Multi-gap Resistive…

Instrumentation and Detectors · Physics 2018-07-02 Rajesh Ganai , Shaifali Mehta , Mehulkumar Shiroya , Mitali Mondal , Zubayer Ahammed , Subhasis Chattopadhyay