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The fast scintillation decay time and the high scintillation yield of liquid xenon makes it an appropriate material for nuclear medicine. Moreover, being a continuous medium with a uniform response, liquid xenon allows one to avoid most of…

An explicit positronium (Ps) source model was implemented in Geant4 to provide direct event-level control over annihilation channel selection, decay timing, and photon emission topology. The implementation supports direct annihilation,…

Medical Physics · Physics 2026-04-29 Jason G Parker

Scanning transmission electron microscopy (STEM) has become the technique of choice for quantitative characterization of atomic structure of materials, where the minute displacements of atomic columns from high-symmetry positions can be…

Materials Science · Physics 2021-10-05 Kevin M. Roccapriore , Nicole Creange , Maxim Ziatdinov , Sergei V. Kalinin

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

Liquid xenon offers several features, which make it suitable for applications in nuclear medicine, such as high scintillation yield and fast scintillation decay time. Moreover, being a continuous medium with a uniform response, liquid xenon…

Instrumentation and Detectors · Physics 2021-03-02 Carmen Romo-Luque

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

The National Electrical Manufacturers Association's (NEMA) NU 4-2008 standard specifies methodology for evaluating the performance of small-animal PET scanners. The standard's goal is to enable comparison of different PET scanners over a…

Medical Physics · Physics 2020-03-03 Patrick Hallen , David Schug , Volkmar Schulz

The low cost and high resolution gas-based Multi-gap Resistive Plate Chamber (MRPC) opens a new possibility to find an efficient alternative detector for Time of Flight (TOF) based Positron Emission Tomography, where the sensitivity of the…

Instrumentation and Detectors · Physics 2011-06-30 A. Banerjee , S. Chattopadhyay

Particle therapy relies on up-to-date knowledge of the stopping power of the patient tissues to deliver the prescribed dose distribution. The stopping power describes the average particle motion, which is encoded in the distribution of…

Beam tests using tracking telescopes are a standard method for determining the spatial resolution of detectors. This requires the precise knowledge of the position resolution of beam tracks reconstructed at the Device Under Test (DUT). A…

Instrumentation and Detectors · Physics 2025-01-13 M. Antonello , L. Eikelmann , E. Garutti , R. Klanner , J. Schwandt , G. Steinbrück , A. Vauth

Positron Emission Tomography (PET) is an imaging technique which can be used to investigate chemical changes in human biological processes such as cancer development or neurochemical reactions. Most dynamic PET scans are currently analyzed…

Applications · Statistics 2014-11-11 Ci-Ren Jiang , John A D Aston , Jane-Ling Wang

Artificial intelligence (AI) is entering medical imaging, mainly enhancing image reconstruction. Nevertheless, improvements throughout the entire processing, from signal detection to computation, potentially offer significant benefits. This…

Machine Learning · Computer Science 2023-10-27 Stephan Naunheim , Yannick Kuhl , David Schug , Volkmar Schulz , Florian Mueller

The high cost and low image quality traditionally associated with proton computed tomography (pCT) have prevented it from seeing significant use in clinical settings. A cheap, compact, high-density scintillating glass detector capable of…

Medical Physics · Physics 2022-06-22 Adam Zieser , Ugur Akgun , Yasar Onel

GePEToS is a simulation framework developed over the last few years for assessing the instrumental performance of future PET scanners. It is based on Geant4, written in Object-Oriented C++ and runs on Linux platforms. The validity of…

Medical Physics · Physics 2015-06-26 S. Jan , J. Collot , M. -L. Gallin-Martel , P. Martin , F. Mayet , E. Tournefier

The international PEN collaboration aims to obtain the branching ratio for the pion electronic decay $\pi^+ \to e^+\nu_e(\gamma)$, aka $\pi_{e2}$, to a relative precision of $5\times 10^{-4}$ or better. The PEN apparatus comprises a number…

Instrumentation and Detectors · Physics 2021-07-07 C. J. Glaser , D. Pocanic , A. van der Schaaf , V. A. Baranov , N. V. Khomutov , N. P. Kravchuk , N. A. Kuchinsky

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

We have analyzed and compared the performance of two novel fast-neutron imaging methods with time-of-flight spectroscopy capability. Using MCNP and GEANT code simulations of neutron and charged-particle transport in the detectors, key…

Instrumentation and Detectors · Physics 2009-11-10 D. Vartsky , I. Mor , M. B. Goldberg , I. Mardor , G. Feldman , D. Bar , A. Shor , V. Dangendorf , G. Laczko , A. Breskin , R. Chechik

Purpose: The scattering phenomenon creates degrading effects in positron emission tomography (PET) and the corresponding events are rejected conventionally. We have proposed a mathematical model to retrace the original line of response of…

Medical Physics · Physics 2022-04-05 Satyajit Ghosh , Pragya Das

This paper describes the characterization of crystal matrices and silicon photomultiplier arrays for a novel Positron Emission Tomography (PET) detector, namely the external plate of the EndoTOFPET-US system. The EndoTOFPET-US collaboration…

An innovative particle detector that offers a compelling combination of cost-effectiveness and high accuracy is introduced. The detector features plastic scintillators paired with a sparse arrangement of SiPMs, strategically positioned…

Instrumentation and Detectors · Physics 2024-10-15 Yoav Simhony , Alex Segal , Yuri Orlov , Ofer Amrani , Erez Etzion