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Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

Infectious disease transmission in human populations has a complex two-way interaction with changes in host behaviour. It is increasingly recognised that incorporating adaptive behavioural change into epidemic models is important for…

Populations and Evolution · Quantitative Biology 2026-04-14 Michael J. Plank , Matt Ryan , Lloyd Chapman , Roslyn I. Hickson , Thomas House , Emma McBryde , James M. McCaw

We formulate models for the spread of infection on networks that are amenable to analysis in the large population limit. We distinguish three different levels: (1) binding sites, (2) individuals, and (3) the population. In the tradition of…

Populations and Evolution · Quantitative Biology 2017-03-03 Ka Yin Leung , Odo Diekmann

We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…

Physics and Society · Physics 2022-12-08 S. P. Lukyanets , I. S. Gandzha , O. V. Kliushnichenko

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

In the infectious disease literature, significant effort has been devoted to studying dynamics at a single scale. For example, compartmental models describing population-level dynamics are often formulated using differential equations. In…

Populations and Evolution · Quantitative Biology 2025-04-16 Yuan Yin , Jennifer A. Flegg , Mark B. Flegg

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

We combine a pedestrian dynamics model with a contact tracing method to simulate the initial spreading of a highly infectious airborne disease in a confined environment. We focus on a medium size population (up to 1000 people) with a small…

Physics and Society · Physics 2020-04-22 Krithika Rathinakumar , Annalisa Quaini

Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space…

Populations and Evolution · Quantitative Biology 2014-12-18 Chiara Poletto , Sandro Meloni , Ashleigh Van Metre , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Infection dynamics have been studied extensively on complex networks, yielding insight into the effects of heterogeneity in contact patterns on disease spread. Somewhat separately, metapopulations have provided a paradigm for modeling…

Physics and Society · Physics 2013-08-09 Jason Hindes , Sarabjeet Singh , Christopher R. Myers , David J. Schneider

The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and…

Physics and Society · Physics 2019-10-02 Wei Wang , Quan-Hui Liu , Junhao Liang , Yanqing Hu , Tao Zhou

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

Probability · Mathematics 2025-11-07 Berk Tan Perçin

Infection spread among individuals is modelled with a continuous time Markov chain, in which subject interactions depend on their distance in space. The well known SIR model and non local variants of the latter are then obtained as large…

Probability · Mathematics 2023-09-27 Franco Flandoli , Francesco Grotto , Andrea Papini , Cristiano Ricci

We consider Susceptible-Infected-Recovered (SIR) models on dense dynamic random graphs, in which the joint dynamics of vertices and edges are co-evolutionary, i.e., they influence each other bidirectionally. In particular, edges appear and…

Probability · Mathematics 2026-02-17 Simone Baldassarri , Peter Braunsteins , Frank den Hollander , Michel Mandjes

We propose an epidemic compartment model, which includes mortality caused by the disease, but excludes demographic birth and death processes. Individuals are represented by random walkers, which are in one of the following states…

We consider a stochastic epidemic model with sideward contact tracing. We assume that infection is driven by interactions within mixing events (gatherings of two or more individuals). Once an infective is diagnosed, each individual who was…

Populations and Evolution · Quantitative Biology 2025-03-28 Dongni Zhang , Martina Favero

Most epidemic processes on networks can be modelled by a compartmental model, that specifies the spread of a disease in a population. The corresponding compartmental graph describes how the viral state of the nodes (individuals) changes…

Physics and Society · Physics 2023-11-29 Massimo A. Achterberg , Piet Van Mieghem

We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…

Populations and Evolution · Quantitative Biology 2022-03-03 Michael Bestehorn , Thomas M. Michelitsch , Bernard A. Collet , Alejandro P. Riascos , Andrzej F. Nowakowski

In this paper we investigate a susceptible-infected-susceptible (SIS) epidemic model describing data dissemination in opportunistic networks with heterogeneous setting of transmission parameters. We obtained the estimation of the final…

Social and Information Networks · Computer Science 2014-03-28 Vadim Alexeev , Liudmila Rozanova , Alexander Temerev

The structure of heterogeneous networks and human mobility patterns profoundly influence the spreading of endemic diseases. In small-scale communities, individuals engage in social interactions within confined environments, such as homes…

Physics and Society · Physics 2025-05-20 Yusheng Li , Yichao Yao , Minyu Feng , Tina P. Benko , Matjaž Perc , Jernej Završnik