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Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Yan , Jinzheng Cai , Dakai Jin , Shun Miao , Dazhou Guo , Adam P. Harrison , Youbao Tang , Jing Xiao , Jingjing Lu , Le Lu

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

Nucleus segmentation is an important analysis task in digital pathology. However, methods for automatic segmentation often struggle with new data from a different distribution, requiring users to manually annotate nuclei and retrain…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Titus Griebel , Anwai Archit , Constantin Pape

Deep learning models trained with large amounts of data have become a recent and effective approach to predictive problem solving -- these have become known as "foundation models" as they can be used as fundamental tools for other…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 José Guilherme de Almeida , Nuno M. Rodrigues , Sara Silva , Nickolas Papanikolaou

Semi-supervised learning has attracted much attention due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods, which is especially important for medical image segmentation which…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yichi Zhang , Jin Yang , Yuchen Liu , Yuan Cheng , Yuan Qi

The recently proposed Segment Anything Model (SAM) is a general tool for image segmentation, but it requires additional adaptation and careful fine-tuning for medical image segmentation, especially for small, irregularly-shaped, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Yaxi Chen , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

The field of medical image segmentation is hindered by the scarcity of large, publicly available annotated datasets. Not all datasets are made public for privacy reasons, and creating annotations for a large dataset is time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Iira Häkkinen , Iaroslav Melekhov , Erik Englesson , Hossein Azizpour , Juho Kannala

Foundation medical segmentation models, with MedSAM being the most popular, have achieved promising performance across organs and lesions. However, MedSAM still suffers from compromised performance on specific lesions with intricate…

Quantitative Methods · Quantitative Biology 2025-07-16 Kecheng Chen , Xinyu Luo , Tiexin Qin , Jie Liu , Hui Liu , Victor Ho Fun Lee , Hong Yan , Haoliang Li

Recently, the Segment Anything Model (SAM) has demonstrated promising segmentation capabilities in a variety of downstream segmentation tasks. However in the context of universal medical image segmentation there exists a notable performance…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Chao Qin , Jiale Cao , Huazhu Fu , Fahad Shahbaz Khan , Rao Muhammad Anwer

Tumor lesion segmentation on CT or MRI images plays a critical role in cancer diagnosis and treatment planning. Considering the inherent differences in tumor lesion segmentation data across various medical imaging modalities and equipment,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Hairong Shi , Songhao Han , Shaofei Huang , Yue Liao , Guanbin Li , Xiangxing Kong , Hua Zhu , Xiaomu Wang , Si Liu

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical…

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Shuangping Huang , Hao Liang , Qingfeng Wang , Chulong Zhong , Zijian Zhou , Miaojing Shi

Foundation segmentation models such as SAM and SAM-2 perform well on natural images but struggle with brain MRIs where structures like the caudate and thalamus lack sharp boundaries and have low contrast. Rather than fine tune these models…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Keith Moore

Accurate segmentation of 3D medical images is critical for clinical applications like disease assessment and treatment planning. While the Segment Anything Model 2 (SAM2) has shown remarkable success in video object segmentation by…

Image and Video Processing · Electrical Eng. & Systems 2025-10-13 Yeqing Yang , Le Xu , Lixia Tian

Volumetric segmentation is important in medical imaging, but current methods face challenges like requiring lots of manual annotations and being tailored to specific tasks, which limits their versatility. General segmentation models used…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Zifan Chen , Xinyu Nan , Jiazheng Li , Jie Zhao , Haifeng Li , Ziling Lin , Haoshen Li , Heyun Chen , Yiting Liu , Lei Tang , Li Zhang , Bin Dong

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

Deformable registration is a fundamental task in medical image processing, aiming to achieve precise alignment by establishing nonlinear correspondences between images. Traditional methods offer good adaptability and interpretability but…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Jing Hu , Kaiwei Yu , Hongjiang Xian , Shu Hu , Xin Wang

Segmentation in medical imaging is a critical component for the diagnosis, monitoring, and treatment of various diseases and medical conditions. Presently, the medical segmentation landscape is dominated by numerous specialized deep…

The advent of foundation models signals a new era in artificial intelligence. The Segment Anything Model (SAM) is the first foundation model for image segmentation. In this study, we evaluate SAM's ability to segment features from eye…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Virmarie Maquiling , Sean Anthony Byrne , Diederick C. Niehorster , Marcus Nyström , Enkelejda Kasneci
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