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Accurate segmentation of anatomical structures and pathological regions in medical images is crucial for diagnosis, treatment planning, and disease monitoring. While the Segment Anything Model (SAM) and its variants have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Yiqing Shen , Xinyuan Shao , Blanca Inigo Romillo , David Dreizin , Mathias Unberath

Recent advancements in large foundation models have shown promising potential in the medical industry due to their flexible prompting capability. One such model, the Segment Anything Model (SAM), a prompt-driven segmentation model, has…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Qi Wu , Yuyao Zhang , Marawan Elbatel

Foundation models are experiencing a surge in popularity. The Segment Anything model (SAM) asserts an ability to segment a wide spectrum of objects but required supervised training at unprecedented scale. We compared SAM's performance…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Danielle Ferreira , Rima Arnaout

The Medical Segment Anything Model (MedSAM) has shown remarkable performance in medical image segmentation, drawing significant attention in the field. However, its sensitivity to varying prompt types and locations poses challenges. This…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Nan Zhou , Ke Zou , Kai Ren , Mengting Luo , Linchao He , Meng Wang , Yidi Chen , Yi Zhang , Hu Chen , Huazhu Fu

The Segment Anything Model (SAM) has achieved a notable success in two-dimensional image segmentation in natural images. However, the substantial gap between medical and natural images hinders its direct application to medical image…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Quan Quan , Fenghe Tang , Zikang Xu , Heqin Zhu , S. Kevin Zhou

While foundation models in radiology are expected to be applied to various clinical tasks, computational cost constraints remain a major challenge when training on 3D-CT volumetric data. In this study, we propose TotalFM, a radiological…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Kohei Yamamoto , Tomohiro Kikuchi

The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi

Medical imaging is essential for the diagnosis and treatment of diseases, with medical image segmentation as a subtask receiving high attention. However, automatic medical image segmentation models are typically task-specific and struggle…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Ruochen Gao , Donghang Lyu , Marius Staring

The Segment Anything Model (SAM) has set a new standard in interactive image segmentation, offering robust performance across various tasks. However, its significant computational requirements limit its deployment in real-time or…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Kunal Dasharath Patil , Gowthamaan Palani , Ganapathy Krishnamurthi

The Segment Anything Model (SAM) has demonstrated impressive performance in zero-shot promptable segmentation on natural images. The recently released Segment Anything Model 2 (SAM 2) claims to outperform SAM on images and extends the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-16 Sourya Sengupta , Satrajit Chakrabarty , Ravi Soni

Medical Image Foundation Models have proven to be powerful tools for mask prediction across various datasets. However, accurately assessing the uncertainty of their predictions remains a significant challenge. To address this, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Xin Wang , Xiaoyu Liu , Peng Huang , Pu Huang , Shu Hu , Hongtu Zhu

Skin cancer is a prevalent and potentially fatal disease that requires accurate and efficient diagnosis and treatment. Although manual tracing is the current standard in clinics, automated tools are desired to reduce human labor and improve…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Mingzhe Hu , Yuheng Li , Xiaofeng Yang

Segmentation of cellular structures in electron microscopy (EM) images is fundamental to analyzing the morphology of neurons and glial cells in the healthy and diseased brain tissue. Current neuronal segmentation applications are based on…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Zewen Zhuo , Ilya Belevich , Ville Leinonen , Eija Jokitalo , Tarja Malm , Alejandra Sierra , Jussi Tohka

Recent "segment anything" efforts show promise by learning from large-scale data, but adapting such models directly to medical images remains challenging due to the complexity of medical data, noisy annotations, and continual learning…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Zhiling Yan , Sifan Song , Dingjie Song , Yiwei Li , Rong Zhou , Weixiang Sun , Zhennong Chen , Sekeun Kim , Hui Ren , Tianming Liu , Quanzheng Li , Xiang Li , Lifang He , Lichao Sun

Brain tumor segmentation presents a formidable challenge in the field of Medical Image Segmentation. While deep-learning models have been useful, human expert segmentation remains the most accurate method. The recently released Segment…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Mohammad Peivandi , Jason Zhang , Michael Lu , Dongxiao Zhu , Zhifeng Kou

Medical image segmentation involves partitioning medical images into meaningful regions, with a focus on identifying anatomical structures and lesions. It has broad applications in healthcare, and deep learning methods have enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Donghang Lyu , Ruochen Gao , Marius Staring

Recently, large foundation models trained on vast datasets have demonstrated exceptional capabilities in feature extraction and general feature representation. The ongoing advancements in deep learning-driven large models have shown great…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Meiqi Hu , Lingzhi Lu , Chengxi Han , Xiaoping Liu

The newly released Segment Anything Model (SAM) is a popular tool used in image processing due to its superior segmentation accuracy, variety of input prompts, training capabilities, and efficient model design. However, its current model is…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Aimee Guo , Grace Fei , Hemanth Pasupuleti , Jing Wang

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

Leveraging the Segment Anything Model (SAM) for medical image segmentation remains challenging due to its limited adaptability across diverse medical domains. Although fine-tuned variants, such as MedSAM, improve performance in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jianghao Wu , Yicheng Wu , Yutong Xie , Wenjia Bai , You Zhang , Feilong Tang , Yulong Li , Imran Razzak , Daniel F Schmidt , Yasmeen George