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Multi-mode fibers (MMFs) and single-mode fibers (SMFs) are widely used in optical communication networks. MMFs are the practical choice in terms of cost in applications that require short distances. Beyond that, SMFs are necessary because…

Optics · Physics 2023-02-22 Oussama Korichi , Markus Hiekkamäki , Robert Fickler

Fluorescence microscopic imaging in centimeter-deep tissue has been highly sought-after for many years because much interesting in vivo micro-information, such as microcirculation, tumor angiogenesis, and metastasis, may deeply locate in…

Multimode fibres offer the advantages of high resolution and miniaturization over single mode fibers in the field of optical imaging. However, multimode fibre's imaging is susceptible to perturbations of MMF that can lead to secondary…

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Fluorescence microscopes can record the dynamics of living cells with high spatio-temporal resolution in a single plane. However, monitoring rapid and dim fluorescence fluctuations, e.g induced by neuronal activity in the brain, remains…

Optical fibers are widely used in bioimaging systems as flexible endoscopes capable of low-invasive penetration inside hollow tissue cavities. Here, we report on the technique which allows magnetic resonance imaging (MRI) of hollow-core…

The wavelength and state of polarization (SOP) are fundamental properties of an optical field which are essential for applications in optical communications, imaging and other fields. However, it is challenging for existing spectrometers…

Optics · Physics 2025-02-25 Yuxuan Xiong , Hao Wu , Mingming Zhang , Yucheng Yao , Ming Tang

In vivo calcium imaging through microscopes has enabled deep brain imaging of previously inaccessible neuronal populations within the brains of freely moving subjects. However, microendoscopic data suffer from high levels of background…

Event-based image sensors provide microsecond temporal resolution but lack spectral discrimination, whereas diffractive spectral imagers encode wavelength information at conventional frame rates. We introduce a fluorescence microscopy…

Optics · Physics 2026-03-20 Richard G. Baird , Boyden Myers , Erik M. Jorgensen , Rajesh Menon

Space-division multiplexing (SDM) is one of the key enabling technologies to increase the capacity of fiber communication systems. However, implementing SDM-based systems using multimode fiber has been challenging with the need for compact,…

Optics · Physics 2023-11-08 Wu Zhou , Zunyue Zhang , Hao Chen , Hon Ki Tsang , Yeyu Tong

Multimode fiber (MMF) has been proven to have good potential in imaging and optical communication because of its advantages of small diameter and large mode numbers. However, due to the mode coupling and modal dispersion, it is very…

Optics · Physics 2025-05-15 Minyu Fan , Kun Liu , Jie Zhu , Yu Cao , Sha Wang

Head-mounted miniaturized microscopes, commonly known as miniscopes, have undergone rapid development and seen widespread adoption over the past two decades, enabling the imaging of neural activity in freely-behaving animals such as…

Neurons and Cognition · Quantitative Biology 2026-03-13 Weijian Zong , Weijian Yang

Multi-photon microscopy is a powerful tool in biomolecular research. Less complex and more cost effective excitation light sources will make this technique accessible to a broader community. Especially semiconductor diode seeded fiber…

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial method for white matter (WM) parcellation to enable analysis of brains structural connectivity in health and disease. Current fiber clustering strategies primarily use…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Bocheng Guo , Jin Wang , Yijie Li , Junyi Wang , Mingyu Gao , Puming Feng , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

When light propagates through opaque material, the spatial information it holds becomes scrambled, but not necessarily lost. Two classes of techniques have emerged to recover this information: methods relying on optical memory effects, and…

When light propagates through a multimode optical fibre (MMF), the spatial information it carries is scrambled. Wavefront shaping can undo this scrambling, typically one spatial mode at a time - enabling deployment of MMFs as ultra-thin…

In many laboratories, conventional bright-field transmission microscopes are available to study the structure and organization principles of fibrous tissue samples, but they usually provide only 2D information. To access the third…

Magnetic Resonance Fingerprinting (MRF) is a time-efficient approach to quantitative MRI, enabling the mapping of multiple tissue properties from a single, accelerated scan. However, achieving accurate reconstructions remains challenging,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-19 Perla Mayo , Carolin M. Pirkl , Alin Achim , Bjoern H. Menze , Mohammad Golbabaee

Holographic wavefront manipulation enables converting hair-thin multimode optical fibres into minimally invasive lensless imaging instruments conveying much higher information densities than conventional endoscopes. Their most prominent…

In the domain of disordered photonics, the characterization of optically opaque materials for light manipulation and imaging is a primary aim. Among various complex devices, multi-mode optical fibers stand out as cost-effective and…