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Parkinson's disease (PD) is a neurodegenerative condition characterized by notable motor and non-motor manifestations. The assessment tool known as the Unified Parkinson's Disease Rating Scale (UPDRS) plays a crucial role in evaluating the…

Sound · Computer Science 2025-02-14 Arman Mohammadigilani , Hani Attar , Hamidreza Ehsani Chimeh , Mostafa Karami

Spatio-temporal data sets are rapidly growing in size. For example, environmental variables are measured with ever-higher resolution by increasing numbers of automated sensors mounted on satellites and aircraft. Using such data, which are…

Methodology · Statistics 2019-11-14 Marcin Jurek , Matthias Katzfuss

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

Neurons and Cognition · Quantitative Biology 2018-11-16 Patrick Schwab , Walter Karlen

We search for digital biomarkers from Parkinson's Disease by observing approximate repetitive patterns matching hypothesized step and stride periodic cycles. These observations were modeled as a cycle of hidden states with randomness…

Quantitative Methods · Quantitative Biology 2017-11-15 Avinash Bukkittu , Baihan Lin , Trung Vu , Itsik Pe'er

Remote photoplethysmography (rPPG) is an attractive method for noninvasive, convenient and concomitant measurement of physiological vital signals. Public benchmark datasets have served a valuable role in the development of this technology…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Jiankai Tang , Kequan Chen , Yuntao Wang , Yuanchun Shi , Shwetak Patel , Daniel McDuff , Xin Liu

People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-05-25 Mohammadreza Iman , Amy Giuntini , Hamid Reza Arabnia , Khaled Rasheed

This paper introduces a stochastic hybrid system (SHS) framework in state space model to capture sensor, communication, and system contingencies in modern power systems (MPS). Within this new framework, the paper concentrates on the…

Systems and Control · Electrical Eng. & Systems 2024-01-31 Shuo Yuan , Le Yi Wang , George Yin , Masoud H. Nazari

Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The existing assessment method for PD is usually the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) to assess the severity of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Xiang Xiang , Zihan Zhang , Jing Ma , Yao Deng

Parkinson's disease (PD) is a slowly progressive debilitating neurodegenerative disease which is prominently characterised by motor symptoms. Indoor localisation, including number and speed of room to room transitions, provides a proxy…

Machine Learning · Computer Science 2022-05-13 Ferdian Jovan , Ryan McConville , Catherine Morgan , Emma Tonkin , Alan Whone , Ian Craddock

Estimating the state of an environment from high-dimensional, multimodal, and noisy observations is a fundamental challenge in reinforcement learning (RL). Traditional approaches rely on probabilistic models to account for the uncertainty,…

Machine Learning · Computer Science 2026-02-13 Alfredo Reichlin , Adriano Pacciarelli , Danica Kragic , Miguel Vasco

Speech-language pathologists (SLPs) frequently use vocal exercises in the treatment of patients with speech disorders. Patients receive treatment in a clinical setting and need to practice outside of the clinical setting to generalize…

Computers and Society · Computer Science 2016-05-23 Harishchandra Dubey , J. Cody Goldberg , Kunal Mankodiya , Leslie Mahler

Spurred in part by the ever-growing number of sensors and web-based methods of collecting data, the use of Intensive Longitudinal Data (ILD) is becoming more common in the social and behavioural sciences. The ILD collected in this field are…

Methodology · Statistics 2022-01-25 Jasper Ginn , Sebastian Mildiner Moraga , Emmeke Aarts

Longitudinal voice biomarkers provide a non-invasive source of information for monitoring Parkinson's disease progression, but their statistical analysis is difficult because repeated measurements from the same subject are correlated,…

Machine Learning · Statistics 2026-04-28 Ran Tong , Lanruo Wang , Tong Wang , Wei Yan

Complex multilayer network datasets have become ubiquitous in various applications, including neuroscience, social sciences, economics, and genetics. Notable examples include brain connectivity networks collected across multiple patients or…

Social and Information Networks · Computer Science 2026-03-06 Alexander Kagan , Peter W. MacDonald , Elizaveta Levina , Ji Zhu

Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint…

Many diseases, including cancer and chronic conditions, require extended treatment periods and long-term strategies. Machine learning and AI research focusing on electronic health records (EHRs) have emerged to address this need. Effective…

We investigate nonlinear state-space models without a closed-form transition density, and propose reformulating such models over their latent noise variables rather than their latent state variables. In doing so the tractable noise density…

Computation · Statistics 2013-12-11 Lawrence M. Murray , Emlyn M. Jones , John Parslow

Speech is a noninvasive digital phenotype that can offer valuable insights into mental health conditions, but it is often treated as a single modality. In contrast, we propose the treatment of patient speech data as a trimodal multimedia…

Computation and Language · Computer Science 2025-07-24 Mai Ali , Christopher Lucasius , Tanmay P. Patel , Madison Aitken , Jacob Vorstman , Peter Szatmari , Marco Battaglia , Deepa Kundur

This paper considers a representation learning strategy to model speech signals from patients with Parkinson's disease and cleft lip and palate. In particular, it compares different parametrized representation types such as wideband and…

Audio and Speech Processing · Electrical Eng. & Systems 2022-09-20 Gabriel Figueiredo Miller , Juan Camilo Vásquez-Correa , Juan Rafael Orozco-Arroyave , Elmar Nöth

Clinical patient records are an example of high-dimensional data that is typically collected from disparate sources and comprises of multiple likelihoods with noisy as well as missing values. In this work, we propose an unsupervised…

Machine Learning · Statistics 2021-04-21 Siddharth Ramchandran , Miika Koskinen , Harri Lähdesmäki