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Motivation: Next Generation Sequencing technologies revolutionized many fields in biology by enabling the fast and cheap sequencing of large amounts of genomic data. The ever increasing sequencing capacities enabled by current sequencing…

Genomics · Quantitative Biology 2012-07-24 Himanshu Asnani , Dinesh Bharadia , Mainak Chowdhury , Idoia Ochoa , Itai Sharon , Tsachy Weissman

Storing and archiving data produced by next-generation sequencing (NGS) is a huge burden for research institutions. Reference-based compression algorithms are effective in dealing with these data. Our work focuses on compressing FASTQ…

Information Theory · Computer Science 2024-04-04 Yuanjian Liu , Huihao Luo , Zhijun Han , Yao Hu , Yehui Yang , Kyle Chard , Sheng Di , Ian Foster , Jiesheng Wu

Motivation: High-throughput sequencing (HTS) enables population-scale genomics but generates massive datasets, creating bottlenecks in storage, transfer, and analysis. FASTQ, the standard format for over two decades, stores one byte per…

Motivation The Burrows-Wheeler transform (BWT) is the foundation of many algorithms for compression and indexing of text data, but the cost of computing the BWT of very large string collections has prevented these techniques from being…

Data Structures and Algorithms · Computer Science 2015-03-20 Anthony J. Cox , Markus J. Bauer , Tobias Jakobi , Giovanna Rosone

Error-bounded lossy compression has been effective in significantly reducing the data storage/transfer burden while preserving the reconstructed data fidelity very well. Many error-bounded lossy compressors have been developed for a wide…

The Burrows-Wheeler-Transform (BWT) is an invertible permutation of a text known to be highly compressible but also useful for sequence analysis, what makes the BWT highly attractive for lossless data compression. In this paper, we present…

Data Structures and Algorithms · Computer Science 2018-04-06 Uwe Baier

This paper proposes a new method that combines check-pointing methods with error-controlled lossy compression for large-scale high-performance Full-Waveform Inversion (FWI), an inverse problem commonly used in geophysical exploration. This…

Error-bounded lossy compression has been widely adopted in many scientific domains because it can address the challenges in storing, transferring, and analyzing unprecedented amounts of scientific data. Although error-bounded lossy…

Databases · Computer Science 2025-07-15 Jinyang Liu , Pu Jiao , Kai Zhao , Xin Liang , Sheng Di , Franck Cappello

Efficient lossless compression is essential for minimizing storage costs and transmission overhead while preserving data integrity. Traditional compression techniques, such as dictionary-based and statistical methods, often struggle to…

Artificial Intelligence · Computer Science 2026-02-13 Mahdi Khodabandeh , Ghazal Shabani , Arash Yousefi Jordehi , Seyed Abolghasem Mirroshandel

We present a new semi-external algorithm that builds the Burrows--Wheeler transform variant of Bauer et al. (a.k.a., BCR BWT) in linear expected time. Our method uses compression techniques to reduce computational costs when the input is…

Data Structures and Algorithms · Computer Science 2023-08-15 Diego Díaz-Domínguez , Gonzalo Navarro

Motivation: FASTQ is a standard file format for DNA sequencing data which stores both nucleotides and quality scores. A typical sequencing study can easily generate hundreds of gigabytes of FASTQ files, while public archives such as ENA and…

Genomics · Quantitative Biology 2014-06-18 Lilian Janin , Ole Schulz-Trieglaff , Anthony J. Cox

This paper introduces a novel technique to preserve spectral features in lossy compression based on a novel fast Fourier correction algorithm\added{ for regular-grid data}. Preserving both spatial and frequency representations of data is…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-06 Congrong Ren , Robert Underwood , Sheng Di , Emrecan Kutay , Zarija Lukic , Aylin Yener , Franck Cappello , Hanqi Guo

Increasing data volumes from scientific simulations and instruments (supercomputers, accelerators, telescopes) often exceed network, storage, and analysis capabilities. The scientific community's response to this challenge is scientific…

Traditional lossless text compression preserves every byte, but its gains on natural language are often modest in realistic operating regimes. We study \emph{lossy semantic text compression}, where the encoder strategically deletes parts of…

Computation and Language · Computer Science 2026-05-29 Yuchun Zou , Junhong Tong , Jun Li

Long-term location tracking, where trajectory compression is commonly used, has gained high interest for many applications in transport, ecology, and wearable computing. However, state-of-the-art compression methods involve high space-time…

Data Structures and Algorithms · Computer Science 2014-12-09 Jiajun Liu , Kun Zhao , Philipp Sommer , Shuo Shang , Brano Kusy , Raja Jurdak

Motivation: Rapid technological progress in DNA sequencing has stimulated interest in compressing the vast datasets that are now routinely produced. Relatively little attention has been paid to compressing the quality scores that are…

Genomics · Quantitative Biology 2013-05-02 Lilian Janin , Giovanna Rosone , Anthony J. Cox

Today's scientific high performance computing (HPC) applications or advanced instruments are producing vast volumes of data across a wide range of domains, which introduces a serious burden on data transfer and storage. Error-bounded lossy…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-01 Xiaodong Yu , Sheng Di , Kai Zhao , jiannan Tian , Dingwen Tao , Xin Liang , Franck Cappello

The Burrows-Wheeler Transform (BWT) is a fundamental component in many data structures for text indexing and compression, widely used in areas such as bioinformatics and information retrieval. The extended BWT (eBWT) generalizes the…

Data Structures and Algorithms · Computer Science 2025-06-06 Florian Ingels , Anaïs Denis , Bastien Cazaux

With the ever-increasing execution scale of high performance computing (HPC) applications, vast amounts of data are being produced by scientific research every day. Error-bounded lossy compression has been considered a very promising…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-24 Jinyang Liu , Sheng Di , Kai Zhao , Xin Liang , Zizhong Chen , Franck Cappello

Error-bounded lossy compression has been a critical technique to significantly reduce the sheer amounts of simulation datasets for high-performance computing (HPC) scientific applications while effectively controlling the data distortion…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-08-23 Tripti Agarwal , Sheng Di , Jiajun Huang , Yafan Huang , Ganesh Gopalakrishnan , Robert Underwood , Kai Zhao , Xin Liang , Guanpeng Li , Franck Cappello
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