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We study theoretically the thermodynamics, over a broad temperature range (5 C to 125 C), related to hydrated water upon protein unfolding. The hydration effect is modeled as interacting dipoles in an external field, mimicking the influence…

Condensed Matter · Physics 2009-11-07 Audun Bakk , Johan S. Hoye , Alex Hansen

Iron oxide nano particles with nominal Fe2O3 stoichiometry were synthesized by a wet, soft chemical method with the heat treatment temperatures from 250{\deg}C to 900{\deg}C in air. The variation in the structural properties of the nano…

Materials Science · Physics 2011-11-29 Debajeet K. Bora , Artur Braun , Selma Erat , Olga Safonova , Thomas Graule , Edwin C. Constable

Understanding and ultimately controlling the transformations and properties of nanoscale systems, from proteins to synthetic nanomaterial assemblies, is limited by the inability to uncover their dynamics on their characteristic length and…

Measurements of chain conformation in proteins/polyelectrolytes complexes (lysozyme and PSSNa) show that the crossover observed between an open structure -a chain network crosslinked by the proteins, and a globular one - dense globules of ~…

Soft Condensed Matter · Physics 2009-03-31 Jérémie Gummel , Fabrice Cousin , François Boué

We have proposed a model to analyze the growth kinetics of lysozyme crystals/aggregates under non-isothermal conditions. The model was formulated through an analysis of the entropy production of the growth process which was obtained by…

Materials Science · Physics 2011-03-24 I. Santamaria-Holek , Adam Gadomski , J. M. Rubi

Despite numerous efforts from numerical approaches to complement experimental measurements, several fundamental challenges have still hindered one's ability to truly provide an atomistic picture of the nucleation process in nanocrystals.…

We propose a new strategy to improve the self-assembly properties of DNA-functionalised colloids. The problem that we address is that DNA-functionalised colloids typically crystallize in a narrow temperature window, if at all. The…

Soft Condensed Matter · Physics 2013-01-22 B. M. Mognetti , M. E. Leunissen , D. Frenkel

We investigate the competition between spinodal decomposition and dynamical arrest using aqueous solutions of the globular protein lysozyme as a model system for colloids with short-range attractions. We show that quenches below a…

Soft Condensed Matter · Physics 2012-12-10 Frederic Cardinaux , Thomas Gibaud , Anna Stradner , Peter Schurtenberger

The proneness of water to crystallize is a major obstacle to understanding its putative exotic behavior in the supercooled state. It also represents a strong practical limitation to cryopreservation of biological systems. Adding some…

The phase transition between water and ice is ubiquitous and one of the most important phenomena in nature. Here, we performed time-resolved x-ray scattering experiments capturing the melting and recrystallization dynamics of ice. The…

I examine a variety snow crystal growth experiments performed at temperatures near -2 C, as a function of supersaturation, background gas pressure, and crystal morphology. Although the different experimental data were obtained using quite…

Materials Science · Physics 2020-04-15 Kenneth G. Libbrecht

Protein corona formation and nanoparticle aggregation have been heavily discussed over the last years since the lack of fine-mapping of these two combined effects has hindered the targeted delivery evolution and the personalized…

We study the dynamics of hydration water/protein association in folded proteins, using lysozyme and myoglobin as examples. Extensive molecular dynamics simulations are performed to identify underlying mechanisms of the dynamical transition…

Soft Condensed Matter · Physics 2015-05-13 J. Servantie , C. Atilgan , A. R. Atilgan

Motivated by recent experiments showing the promise of noble gases as cryoprotectants, we perform molecular dynamics modeling of phase transitions in water with xenon under cooling. We study the structure and dynamics of xenon water…

Soft Condensed Matter · Physics 2014-07-16 Vasilii I. Artyukhov , Alexander Yu. Pulver , Alex Peregudov , Igor Artyuhov

In the present work, we provide a dielectric study on two differently concentrated aqueous lysozyme solutions in the frequency range from 1 MHz to 40 GHz and for temperatures from 275 to 330 K. We analyze the three dispersion regions,…

Soft Condensed Matter · Physics 2012-03-29 M. Wolf , R. Gulich , P. Lunkenheimer , A. Loidl

Neutron elastic, inelastic and high energy x-ray scattering techniques are used to explore the nature of the polaron order and dynamics in La0.7Ca0.3MnO3. Static polaron correlations develop within a narrow temperature regime as the Curie…

Strongly Correlated Electrons · Physics 2007-08-02 J. W. Lynn , D. N Argyriou , Y. Ren , Y. Chen , Y. M. Mukovskii , D. A. Shulyatev

Protein crystal production is a major bottleneck for the structural characterisation of proteins. To advance beyond large-scale screening, rational strategies for protein crystallization are crucial. Understanding how chemical anisotropy…

Biomolecules · Quantitative Biology 2022-05-03 Amir R. Khan , Susan James , Michelle K. Quinn , Irem Altan , Patrick Charbonneau , Jennifer J. McManus

The viscoelastic properties of thin polymeric films represent a central issue, especially for nanotechnological applications. In particular, it is highly relevant the dependence of viscoelasticity on the temperature. For polystyrene it is…

Confinement breaks the translational symmetry of materials. Such symmetry breaking can be used to obtain configurations that are not otherwise accessible in the bulk. Here, we explore the effect of substrate-liquid interactions on the…

Statistical Mechanics · Physics 2015-12-03 Amir Haji-Akbari , Pablo G. Debenedetti

The study of protein functions attributed to the conformation and fluctuation that are ruled by both the amino acid sequence and thermodynamics, requires thermodynamic quantities given by calorimetry using thermometric techniques. The…

Biological Physics · Physics 2019-05-01 Manabu Ishino , Akio Kishigami , Hiroyuki Kudo , Jongsuck Bae , Tatsuo Nozokido