English

Interplay between Spinodal Decomposition and Glass Formation in Proteins Exhibiting Short-Range Attractions

Soft Condensed Matter 2012-12-10 v1 Materials Science

Abstract

We investigate the competition between spinodal decomposition and dynamical arrest using aqueous solutions of the globular protein lysozyme as a model system for colloids with short-range attractions. We show that quenches below a temperature Ta lead to gel formation as a result of a local arrest of the proteindense phase during spinodal decomposition. The rheological properties of these gels allow us to use centrifugation experiments to determine the local densities of both phases and to precisely locate the gel boundary and the attractive glass line close to and within the unstable region of the phase diagram.

Keywords

Cite

@article{arxiv.0902.0310,
  title  = {Interplay between Spinodal Decomposition and Glass Formation in Proteins Exhibiting Short-Range Attractions},
  author = {Frederic Cardinaux and Thomas Gibaud and Anna Stradner and Peter Schurtenberger},
  journal= {arXiv preprint arXiv:0902.0310},
  year   = {2012}
}