Related papers: Synchronous replication initiation of multiple ori…
A mathematical model of Min oscillation in Escherichia coli is numerically studied. The oscillatory state and hysteretic transition are explained with simpler coupled differential equations. Next, we propose a simple model of cell growth…
In a letter published in Molecular Biology Evolution [10], Chen and Zhang argue that the variation of the mutation rate along the Escherichia coli genome that we recently reported [3] cannot be evolutionarily optimised. To support this…
Synchronization across long neural distances is a functionally important phenomenon. In order to access the mechanistic basis of long-range synchrony, we constructed an experimental model that enables monitoring of spiking activities over…
Being a dual purpose enzyme, the DNA polymerase is responsible for elongation of the newly formed DNA strand as well as cleaving the erroneous growth in case of a misincorporation. The efficiency of replication depends on the coordination…
Formation of hydronium and carbonate ions from CO2 in the aqueous phase is a reversible process and can produce and consume ions. These equilibrium reactions represent molecular electrochemical oscillators with chaotic dynamics. As…
This computational study introduces a theoretical framework for practical, electrochemical fuel generation displaying exponential product yields as functions of time. Exponential reaction scaling is simulated through an autocatalytic cycle…
Individual mRNAs are translated by multiple ribosomes that initiate translation with a few seconds interval. The ribosome speed is codon dependant, and ribosome queuing has been suggested to explain specific data for translation of some…
The cell cycle is a tightly controlled process, yet its underlying genetic network shows marked differences across species. Which of the associated structural features follow solely from the ability to impose the appropriate gene expression…
Collective cell migration lies at the intersection of developmental biology and non-equilibrium physics, where active processes give rise to emergent patterns that are biologically relevant. Here, we investigate dilatational modes--cycles…
We say that a Cellular Automata (CA) is coalescing when its execution on two distinct (random) initial configurations in the same asynchronous mode (the same cells are updated in each configuration at each time step) makes both…
Cellular life requires the presence of a set of biochemical mechanisms in order to maintain a predictable process of growth and division. Several attempts have been made towards the building of minimal protocells from a top-down approach,…
Spike synchrony, which occurs in various cortical areas in response to specific perception, action and memory tasks, has sparked a long-standing debate on the nature of temporal organization in cortex. One prominent view is that this type…
Synchronization is of importance in both fundamental and applied physics, but their demonstration at the micro/nanoscale is mainly limited to low-frequency oscillations like mechanical resonators. Here, we report the synchronization of two…
The mechanism of synchronization of oscillations in two identical coupled flow systems has beenstudied. The time (past the coupling onset) during which a synchronous oscillation regime is establisheddepends on the oscillation phase…
Biological systems are promising substrates for computation because they naturally process environmental information through complex internal dynamics. In this study, we investigate whether bacterial metabolic models can act as physical…
Asynchronously replicated primary-backup databases are commonly deployed to improve availability and offload read-only transactions. To both apply replicated writes from the primary and serve read-only transactions, the backups implement a…
Distributed systems, such as state machine replication, are critical infrastructures for modern applications. Practical distributed protocols make minimum assumptions about the underlying network: They typically assume a partially…
We study the relation between process calculi that differ in their either synchronous or asynchronous interaction mechanism. Concretely, we are interested in the conditions under which synchronous interaction can be implemented using just…
The genetic code underlying protein synthesis is a canonical example of a degenerate biological system. Degeneracies in physical and biological systems can be lifted by external perturbations thus allowing degenerate systems to exhibit a…
Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…