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A fast Bayesian method that seamlessly fuses classification and hypothesis testing via discriminant analysis is developed. Building upon the original discriminant analysis classifier, modelling components are added to identify…

Methodology · Statistics 2019-08-28 Weichang Yu , John T. Ormerod , Michael Stewart

Randomized pre-post designs, with outcomes measured at baseline and follow-ups, have been commonly used to compare the clinical effectiveness of two competing treatments. There are vast, but often conflicting, amount of information in…

Applications · Statistics 2020-07-16 Fei Wan

We consider balanced one-, two- and three-way ANOVA models to test the hypothesis that the fixed factor A has no effect. The other factors are fixed or random. We determine the noncentrality parameter for the exact F-test, describe its…

Methodology · Statistics 2021-07-01 Bernhard Spangl , Norbert Kaiblinger , Peter Ruckdeschel , Dieter Rasch

A formal likelihood ratio hypothesis test for the validity of a parametric regression function is proposed, using a large-dimensional, nonparametric double cone alternative. For example, the test against a constant function uses the…

Methodology · Statistics 2014-06-30 Bodhisattva Sen , Mary Meyer

Statistical tests that compare classification algorithms are univariate and use a single performance measure, e.g., misclassification error, $F$ measure, AUC, and so on. In multivariate tests, comparison is done using multiple measures…

Machine Learning · Statistics 2014-09-17 Olcay Taner Yildiz , Ethem Alpaydin

Modern machine learning methods are often overparametrized, allowing adaptation to the data at a fine level. This can seem puzzling; in the worst case, such models do not need to generalize. This puzzle inspired a great amount of work,…

Machine Learning · Statistics 2021-06-10 Licong Lin , Edgar Dobriban

In clinical studies with paired organs, binary outcomes often exhibit intra-subject correlation and may include a mixture of unilateral and bilateral observations. Under Donner's constant correlation model, we develop three likelihood-based…

Methodology · Statistics 2025-10-22 Jia Zhou , Chang-Xing Ma

A multi-reader multi-case (MRMC) analysis is applied to account for both reader and case variability when evaluating the clinical performance of a medical imaging device or reader performance under different reading modalities. For a…

Quantitative Methods · Quantitative Biology 2023-12-27 Si Wen , Brandon D. Gallas

In the social sciences we are often interested in comparing models specified by parametric equality or inequality constraints. For instance, when examining three group means $\{ \mu_1, \mu_2, \mu_3\}$ through an analysis of variance…

Methodology · Statistics 2025-01-08 Guido Consonni , Roberta Paroli

Studies show that Studies that cardiovascular diseases (CVDs) are malignant for human health. Thus, it is important to have an efficient way of CVD prognosis. In response to this, the healthcare industry has adopted machine learning-based…

Machine Learning · Computer Science 2022-08-02 Mohammed Nowshad Ruhani Chowdhury , Wandong Zhang , Thangarajah Akilan

The performance of a number of different measures of nonlinearity in a time series is compared numerically. Their power to distinguish noisy chaotic data from linear stochastic surrogates is determined by Monte Carlo simulation for a number…

chao-dyn · Physics 2009-10-31 Thomas Schreiber , Andreas Schmitz

In pharmacogenomic studies, biomedical researchers commonly analyze the association between genotype and biological response by using the Kruskal--Wallis test or one-way analysis of variance (ANOVA) after logarithmic transformation of the…

Methodology · Statistics 2020-12-08 Kengo Nagashima , Yasunori Sato , Chikuma Hamada

In this paper, we consider testing the homogeneity of risk differences in independent binomial distributions especially when data are sparse. We point out some drawback of existing tests in either controlling a nominal size or obtaining…

Methodology · Statistics 2018-05-31 Junyong Park , Iris Ivy Gauran

The homogeneity problem for testing if more than two different samples come from the same population is considered for the case of functional data. The methodological results are motivated by the study of homogeneity of electronic devices…

Several treatments are usually compared with a control using the Dunnett test. As an alternative, three variants of the closed testing approach are considered, one with ANOVA-F-tests, one with MCT-GrandMean and one with global Dunnett-tests…

Applications · Statistics 2020-12-09 Ludwig A. Hothorn

In this paper we proposed the alternative test to the two independent and normally distributed samples t test based on the cross variance concept. We present the simulation results of the power and the error rate of the special case of the…

Methodology · Statistics 2015-01-27 Rohmatul Fajriyah

In cell biology, statistical analysis means testing the hypothesis that there was no effect. This weak form of hypothesis testing neglects effect size, is universally misinterpreted, and is disastrously prone to error when combined with…

Other Quantitative Biology · Quantitative Biology 2025-05-13 Josh L. Morgan

At every phase of scientific research, scientists must decide how to allocate limited resources to pursue the research inquiries with the greatest potential. This prioritization dictates which controlled interventions are studied, awarded…

Methodology · Statistics 2022-10-11 Bruce A. Corliss , Yaotian Wang , Heman Shakeri , Philip E. Bourne

The normality assumption for random errors is fundamental in the analysis of variance (ANOVA) models. However, it is rarely subjected to formal testing in practice, and theoretically justified procedures are largely unavailable, especially…

Econometrics · Economics 2026-03-31 Peiwen Jia , Xiaojun Song , Haoyu Wei

Hypothesis testing is one of the most common types of data analysis and forms the backbone of scientific research in many disciplines. Analysis of variance (ANOVA) in particular is used to detect dependence between a categorical and a…

Cryptography and Security · Computer Science 2019-03-05 Marika Swanberg , Ira Globus-Harris , Iris Griffith , Anna Ritz , Adam Groce , Andrew Bray