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Although unsupervised generative modeling of an image dataset using a Variational AutoEncoder (VAE) has been used to detect anomalous images, or anomalous regions in images, recent works have shown that this method often identifies images…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 David Dehaene , Pierre Eline

Multimodal Large Language Models demonstrate strong performance on multimodal benchmarks, yet often exhibit poor robustness when exposed to spurious modality interference, such as irrelevant text in vision understanding, or irrelevant…

Machine Learning · Computer Science 2026-01-30 Rui Cai , Bangzheng Li , Xiaofei Wen , Muhao Chen , Zhe Zhao

This paper introduces a new interpretation of the Variational Autoencoder framework by taking a fully geometric point of view. We argue that vanilla VAE models unveil naturally a Riemannian structure in their latent space and that taking…

Machine Learning · Statistics 2022-11-04 Clément Chadebec , Stéphanie Allassonnière

Unsupervised visual anomaly detection from multi-view images presents a significant challenge: distinguishing genuine defects from benign appearance variations caused by viewpoint changes. Existing methods, often designed for single-view…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xintao Chen , Xiaohao Xu , Bozhong Zheng , Yun Liu , Yingna Wu

Multimodal variational autoencoders (VAEs) have emerged as a powerful framework for survival risk modeling in multiple myeloma by integrating heterogeneous omics and clinical data. However, when trained under survival supervision, standard…

Machine Learning · Computer Science 2026-04-09 Zixuan Chen , Heng Zhang , YuPeng Qin , WenPeng Xing , Qiang Wang , Da Wang , Changting Lin , Meng Han

We propose a framework for the statistical evaluation of variational auto-encoders (VAEs) and test two instances of this framework in the context of modelling images of handwritten digits and a corpus of English text. Our take on evaluation…

Machine Learning · Computer Science 2022-04-08 Claartje Barkhof , Wilker Aziz

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

This work describes an unsupervised method to objectively quantify the abnormality of general anatomical shapes. The severity of an anatomical deformity often serves as a determinant in the clinical management of patients. However,…

Computer Vision and Pattern Recognition · Computer Science 2020-09-17 Wenzheng Tao , Riddhish Bhalodia , Erin Anstadt , Ladislav Kavan , Ross T. Whitaker , Jesse A. Goldstein

Building robust medical machine learning systems requires pretraining strategies that exploit the intrinsic structure present in clinical data. We introduce Multiview Masked Autoencoder (MVMAE), a self-supervised framework that leverages…

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

We propose a robust variational autoencoder with $\beta$ divergence for tabular data (RTVAE) with mixed categorical and continuous features. Variational autoencoders (VAE) and their variations are popular frameworks for anomaly detection…

Machine Learning · Computer Science 2020-06-17 Haleh Akrami , Sergul Aydore , Richard M. Leahy , Anand A. Joshi

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

We propose a new family of optimization criteria for variational auto-encoding models, generalizing the standard evidence lower bound. We provide conditions under which they recover the data distribution and learn latent features, and…

Machine Learning · Computer Science 2017-03-01 Shengjia Zhao , Jiaming Song , Stefano Ermon

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

This paper addresses the challenges of detecting anomalies in cellular networks in an interpretable way and proposes a new approach using variational autoencoders (VAEs) that learn interpretable representations of the latent space for each…

Machine Learning · Computer Science 2023-06-29 Amandeep Singh , Michael Weber , Markus Lange-Hegermann

We propose to learn model invariances as a means of interpreting a model. This is motivated by a reverse engineering principle. If we understand a problem, we may introduce inductive biases in our model in the form of invariances.…

Machine Learning · Computer Science 2020-07-16 An-phi Nguyen , María Rodríguez Martínez

Modern applications increasingly involve many heterogeneous input streams, such as clinical sensors, wearable device data, imaging, and text, each with distinct measurement models, sampling rates, and noise characteristics. We define this…

Machine Learning · Computer Science 2026-03-03 Xing Han , Hsing-Huan Chung , Joydeep Ghosh , Paul Pu Liang , Suchi Saria

This paper proposes a method for detecting anomalies in video data. A Variational Autoencoder (VAE) is used for reducing the dimensionality of video frames, generating latent space information that is comparable to low-dimensional sensory…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Giulia Slavic , Damian Campo , Mohamad Baydoun , Pablo Marin , David Martin , Lucio Marcenaro , Carlo Regazzoni

Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models…

Computers and Society · Computer Science 2021-10-19 Sofia Lahrichi , Maryem Rhanoui , Mounia Mikram , Bouchra El Asri

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger