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From medical diagnosis to autonomous vehicles, critical applications rely on the integration of multiple heterogeneous data modalities. Multimodal Variational Autoencoders offer versatile and scalable methods for generating unobserved…

Machine Learning · Computer Science 2025-02-07 Agathe Senellart , Stéphanie Allassonnière

In recent years, single modality based gait recognition has been extensively explored in the analysis of medical images or other sensory data, and it is recognised that each of the established approaches has different strengths and…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Aite Zhao , Jianbo Li , Junyu Dong , Lin Qi , Qianni Zhang , Ning Li , Xin Wang , Huiyu Zhou

Brain disorders are a major challenge to global health, causing millions of deaths each year. Accurate diagnosis of these diseases relies heavily on advanced medical imaging techniques such as Magnetic Resonance Imaging (MRI) and Computed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Xuran Zhu

Binge eating disorder (BED) is the most prevalent eating disorder. However, current diagnostic frameworks remain largely grounded in symptom-based criteria rather than underlying biological mechanisms, thereby limiting early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Lin Zhao , Qiaohui Gao , Elizabeth Martin , Kurt P. Schulz , Tom Hildebrandt , Robyn Sysko , Tianming Liu , Xiaobo Li

Neurophysiological decoding, fundamental to advancing brain-computer interface (BCI) technologies, has significantly benefited from recent advances in deep learning. However, existing decoding approaches largely remain constrained to…

Signal Processing · Electrical Eng. & Systems 2025-08-07 Di Wu , Yifei Jia , Siyuan Li , Shiqi Zhao , Jie Yang , Mohamad Sawan

Fair and unbiased machine learning is an important and active field of research, as decision processes are increasingly driven by models that learn from data. Unfortunately, any biases present in the data may be learned by the model,…

Machine Learning · Computer Science 2020-02-27 Matthew J. Vowels , Necati Cihan Camgoz , Richard Bowden

Recently Autoencoder(AE) based models are widely used in the field of anomaly detection. A model trained with normal data generates a larger restoration error for abnormal data. Whether or not abnormal data is determined by observing the…

Machine Learning · Computer Science 2021-07-20 JoonSung Lee , YeongHyeon Park

Medical anomaly detection aims to identify abnormal findings using only normal training data, playing a crucial role in health screening and recognizing rare diseases. Reconstruction-based methods, particularly those utilizing autoencoders…

Machine Learning · Computer Science 2024-07-10 Yu Cai , Hao Chen , Kwang-Ting Cheng

Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Vision foundation models like DINOv2 demonstrate remarkable potential in medical imaging despite their origin in natural image domains. However, their design inherently works best for uni-modal image analysis, limiting their effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Viktoria Ehm , Anke Meyer-Baese , Jan C. Peeken , Daniel Rueckert , Benedikt Wiestler

We present two deep generative models based on Variational Autoencoders to improve the accuracy of drug response prediction. Our models, Perturbation Variational Autoencoder and its semi-supervised extension, Drug Response Variational…

Machine Learning · Statistics 2017-07-07 Ladislav Rampasek , Daniel Hidru , Petr Smirnov , Benjamin Haibe-Kains , Anna Goldenberg

Learning from heterogeneous data poses challenges such as combining data from various sources and of different types. Meanwhile, heterogeneous data are often associated with missingness in real-world applications due to heterogeneity and…

Machine Learning · Computer Science 2021-02-26 Yu Gong , Hossein Hajimirsadeghi , Jiawei He , Thibaut Durand , Greg Mori

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

The long-term progression of neurodegenerative diseases is commonly conceptualized as a spatiotemporal diffusion process that consists of a graph diffusion process across the structural brain connectome and a localized reaction process…

Machine Learning · Computer Science 2025-08-12 Tiantian He , Keyue Jiang , An Zhao , Anna Schroder , Elinor Thompson , Sonja Soskic , Frederik Barkhof , Daniel C. Alexander

All neuroimaging modalities have their own strengths and limitations. A current trend is toward interdisciplinary approaches that use multiple imaging methods to overcome limitations of each method in isolation. At the same time…

Methodology · Statistics 2023-03-30 Pratim Guha Niyogi , Martin A. Lindquist , Tapabrata Maiti

Unnormalised latent variable models are a broad and flexible class of statistical models. However, learning their parameters from data is intractable, and few estimation techniques are currently available for such models. To increase the…

Machine Learning · Statistics 2019-02-26 Benjamin Rhodes , Michael Gutmann

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

Multimodal Variational Autoencoders (VAEs) represent a promising group of generative models that facilitate the construction of a tractable posterior within the latent space given multiple modalities. Previous studies have shown that as the…

Machine Learning · Computer Science 2024-12-11 Daniel Wesego , Pedram Rooshenas

Multi-view data from the same source often exhibit correlation. This is mirrored in correlation between the latent spaces of separate variational autoencoders (VAEs) trained on each data-view. A multi-view VAE approach is proposed that…

Machine Learning · Statistics 2025-08-01 Ella S. C. Orme , Marina Evangelou , Ulrich Paquet