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Advances in digital pathology and artificial intelligence (AI) offer promising opportunities for clinical decision support and enhancing diagnostic workflows. Previous studies already demonstrated AI's potential for automated Gleason…

Automated classification of histopathological whole-slide images (WSI) of breast tissue requires analysis at very high resolutions with a large contextual area. In this paper, we present context-aware stacked convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-05-11 Babak Ehteshami Bejnordi , Guido Zuidhof , Maschenka Balkenhol , Meyke Hermsen , Peter Bult , Bram van Ginneken , Nico Karssemeijer , Geert Litjens , Jeroen van der Laak

In this paper, we introduce an unsupervised cancer segmentation framework for histology images. The framework involves an effective contrastive learning scheme for extracting distinctive visual representations for segmentation. The encoder…

Computer Vision and Pattern Recognition · Computer Science 2022-06-20 Yilong Li , Yaqi Wang , Huiyu Zhou , Huaqiong Wang , Gangyong Jia , Qianni Zhang

We propose a new strategy to improve the accuracy and robustness of image classification. First, we train a baseline CNN model. Then, we identify challenging regions in the feature space by identifying all misclassified samples, and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Fadoua Khmaissia , Hichem Frigui

Microsatellite instability (MSI) is a tumor phenotype whose diagnosis largely impacts patient care in colorectal cancers (CRC), and is associated with response to immunotherapy in all solid tumors. Deep learning models detecting MSI tumors…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Charlie Saillard , Olivier Dehaene , Tanguy Marchand , Olivier Moindrot , Aurélie Kamoun , Benoit Schmauch , Simon Jegou

The analysis of the tumor environment on digital histopathology slides is becoming key for the understanding of the immune response against cancer, supporting the development of novel immuno-therapies. We introduce here a novel deep…

Image and Video Processing · Electrical Eng. & Systems 2019-06-27 Ansh Kapil , Tobias Wiestler , Simon Lanzmich , Abraham Silva , Keith Steele , Marlon Rebelatto , Guenter Schmidt , Nicolas Brieu

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

Despite significant research efforts and advancements, cancer remains a leading cause of mortality. Early cancer prediction has become a crucial focus in cancer research to streamline patient care and improve treatment outcomes. Manual…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Samta Rani , Tanvir Ahmad , Sarfaraz Masood , Chandni Saxena

Cancer is still one of the most devastating diseases of our time. One way of automatically classifying tumor samples is by analyzing its derived molecular information (i.e., its genes expression signatures). In this work, we aim to…

Machine Learning · Computer Science 2020-01-16 Mafalda Falcao Ferreira , Rui Camacho , Luis F. Teixeira

In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Abdul Samad Shaik , Shashaank Mattur Aswatha , Rahul Jashvantbhai Pandya

Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Yinsheng He , Xingyu Li

Stacked Auto-Encoder (SAE) is a kind of deep learning algorithm for unsupervised learning. Which has multi layers that project the vector representation of input data into a lower vector space. These projection vectors are dense…

Computer Vision and Pattern Recognition · Computer Science 2016-10-11 Fei Hu , Changjiu Pu , Haowei Gao , Mengzi Tang , Li Li

Improving generalization is a major challenge in audio classification due to labeled data scarcity. Self-supervised learning (SSL) methods tackle this by leveraging unlabeled data to learn useful features for downstream classification…

Audio and Speech Processing · Electrical Eng. & Systems 2021-12-22 Melikasadat Emami , Dung Tran , Kazuhito Koishida

Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Rui Aguiar , Jon Braatz

Domain shift is a problem commonly encountered when developing automated histopathology pipelines. The performance of machine learning models such as convolutional neural networks within automated histopathology pipelines is often…

Image and Video Processing · Electrical Eng. & Systems 2021-07-16 Andrew Moyes , Richard Gault , Kun Zhang , Ji Ming , Danny Crookes , Jing Wang

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor grade and treatment for patients. However, this task is often challenging due to the heterogeneous nature of lung adenocarcinoma and the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-01 Jason W. Wei , Laura J. Tafe , Yevgeniy A. Linnik , Louis J. Vaickus , Naofumi Tomita , Saeed Hassanpour

Histopathological images (HI) encrypt resolution dependent heterogeneous textures & diverse color distribution variability, manifesting in micro-structural surface tissue convolutions. Also, inherently high coherency of cancerous cells…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Sawon Pratiher , Subhankar Chattoraj
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