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Deep neural network models can learn clinically relevant features from millions of histopathology images. However generating high-quality annotations to train such models for each hospital, each cancer type, and each diagnostic task is…

Self-supervised learning (SSL) is a powerful tool in machine learning, but understanding the learned representations and their underlying mechanisms remains a challenge. This paper presents an in-depth empirical analysis of SSL-trained…

Machine Learning · Computer Science 2023-06-01 Ido Ben-Shaul , Ravid Shwartz-Ziv , Tomer Galanti , Shai Dekel , Yann LeCun

Pancreatic cancer will soon be the second leading cause of cancer-related death in Western society. Imaging techniques such as CT, MRI and ultrasound typically help providing the initial diagnosis, but histopathological assessment is still…

Image and Video Processing · Electrical Eng. & Systems 2022-01-26 Pierpaolo Vendittelli , Esther M. M. Smeets , Geert Litjens

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

In digital pathology, whole-slide images (WSIs) are often difficult to handle due to their gigapixel scale, so most approaches train patch encoders via self-supervised learning (SSL) and then aggregate the patch-level embeddings via…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Myeongjang Pyeon , Janghyeon Lee , Minsoo Lee , Juseung Yun , Hwanil Choi , Jonghyun Kim , Jiwon Kim , Yi Hu , Jongseong Jang , Soonyoung Lee

This project aims to break down large pathology images into small tiles and then cluster those tiles into distinct groups without the knowledge of true labels, our analysis shows how difficult certain aspects of clustering tumorous and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Mostafa Ibrahim , Kevin Bryson

Accurate tumour segmentation is vital for various targeted diagnostic and therapeutic procedures for cancer, e.g., planning biopsies or tumour ablations. Manual delineation is extremely labour-intensive, requiring substantial expert time.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Catalina Tan , Yipeng Hu , Shaheer U. Saeed

PURPOSE: Deep learning methods for classifying prostate cancer (PCa) in ultrasound images typically employ convolutional networks (CNNs) to detect cancer in small regions of interest (ROI) along a needle trace region. However, this approach…

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Self-supervised pretraining attempts to enhance model performance by obtaining effective features from unlabeled data, and has demonstrated its effectiveness in the field of histopathology images. Despite its success, few works concentrate…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Zhiyun Song , Penghui Du , Junpeng Yan , Kailu Li , Jianzhong Shou , Maode Lai , Yubo Fan , Yan Xu

Recent research in self-supervised learning (SSL) has shown its capability in learning useful semantic representations from images for classification tasks. Through our work, we study the usefulness of SSL for Fine-Grained Visual…

Computer Vision and Pattern Recognition · Computer Science 2021-05-20 Muhammad Maaz , Hanoona Abdul Rasheed , Dhanalaxmi Gaddam

Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Juexin Zhang , Qifeng Zhong , Ying Weng , Ke Chen

Pathologists find tedious to examine the status of the sentinel lymph node on a large number of pathological scans. The examination process of such lymph node which encompasses metastasized cancer cells is histopathologically organized.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Amit Kumar Jaiswal , Ivan Panshin , Dimitrij Shulkin , Nagender Aneja , Samuel Abramov

Digital pathology (DP) is a new research area which falls under the broad umbrella of health informatics. Owing to its potential for major public health impact, in recent years DP has been attracting much research attention. Nevertheless, a…

Image and Video Processing · Electrical Eng. & Systems 2019-03-12 Xingzhi Yue , Neofytos Dimitriou , Ognjen Arandjelovic

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

In state-of-the-art self-supervised learning (SSL) pre-training produces semantically good representations by encouraging them to be invariant under meaningful transformations prescribed from human knowledge. In fact, the property of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-16 Rumen Dangovski , Li Jing , Charlotte Loh , Seungwook Han , Akash Srivastava , Brian Cheung , Pulkit Agrawal , Marin Soljačić

Background: Transrectal ultrasound guided systematic biopsies of the prostate is a routine procedure to establish a prostate cancer diagnosis. However, the 10-12 prostate core biopsies only sample a relatively small volume of the prostate,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-20 Bojing Liu , Yinxi Wang , Philippe Weitz , Johan Lindberg , Johan Hartman , Lars Egevad , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Deep learning has proven to be a very effective approach for Hyperspectral Image (HSI) classification. However, deep neural networks require large annotated datasets to generalize well. This limits the applicability of deep learning for HSI…

Computer Vision and Pattern Recognition · Computer Science 2022-06-27 Nassim Ait Ali Braham , Lichao Mou , Jocelyn Chanussot , Julien Mairal , Xiao Xiang Zhu

Segmentation of pathological images is a crucial step for accurate cancer diagnosis. However, acquiring dense annotations of such images for training is labor-intensive and time-consuming. To address this issue, Semi-Supervised Learning…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Lanfeng Zhong , Xin Liao , Shaoting Zhang , Guotai Wang