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Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Marcel Bengs , Nils Gessert , Wiebke Laffers , Dennis Eggert , Stephan Westermann , Nina A. Mueller , Andreas O. H. Gerstner , Christian Betz , Alexander Schlaefer

Purpose: An investigation of the challenge of annotating discrete segmentations of brain tumours in ultrasound, with a focus on the issue of aleatoric uncertainty along the tumour margin, particularly for diffuse tumours. A segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Alistair Weld , Luke Dixon , Alfie Roddan , Giulio Anichini , Sophie Camp , Stamatia Giannarou

Dynamic Contrast Enhanced Magnetic Resonance Imaging aids in the detection and assessment of tumor aggressiveness by using a Gadolinium-based contrast agent (GBCA). However, GBCA is known to have potential toxic effects. This risk can be…

Image and Video Processing · Electrical Eng. & Systems 2024-02-06 Sadhana S , Sriprabha Ramanarayanan , Arunima Sarkar , Matcha Naga Gayathri , Keerthi Ram , Mohanasankar Sivaprakasam

In this paper we report results for recognizing colorectal NBI endoscopic images by using features extracted from convolutional neural network (CNN). In this comparative study, we extract features from different layers from different CNN…

Computer Vision and Pattern Recognition · Computer Science 2016-08-25 Toru Tamaki , Shoji Sonoyama , Tsubasa Hirakawa , Bisser Raytchev , Kazufumi Kaneda , Tetsushi Koide , Shigeto Yoshida , Hiroshi Mieno , Shinji Tanaka

We propose a statistical multiscale mapping approach to identify microscopic and molecular heterogeneity across a tumor microenvironment using multiparametric MR (mp-MR). Twenty-nine patients underwent pre-surgical mp-MR followed by…

Medical Physics · Physics 2019-07-26 Jason G Parker , PhD , Emily E Diller , MS , Sha Cao , PhD , Jeremy T Nelson , PhD , Kristen Yeom , MD , Chang Ho , MD , Robert Lober , MD , PhD

Detection of tumors in metastatic colorectal cancer (mCRC) plays an essential role in the early diagnosis and treatment of liver cancer. Deep learning models backboned by fully convolutional neural networks (FCNNs) have become the dominant…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Ramtin Mojtahedi , Mohammad Hamghalam , Richard K. G. Do , Amber L. Simpson

Accurate brain tumor typing requires integrating heterogeneous clinical evidence, including magnetic resonance imaging (MRI), histopathology, and pathology reports, which are often incomplete at the time of diagnosis. We introduce CoRe-BT,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Juampablo E. Heras Rivera , Daniel K. Low , Xavier Xiong , Jacob J. Ruzevick , Daniel D. Child , Wen-wai Yim , Mehmet Kurt , Asma Ben Abacha

Recent years have seen great advancements in the development of deep learning models for histopathology image analysis in digital pathology applications, evidenced by the increasingly common deployment of these models in both research and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Veena Kaustaban , Qinle Ba , Ipshita Bhattacharya , Nahil Sobh , Satarupa Mukherjee , Jim Martin , Mohammad Saleh Miri , Christoph Guetter , Amal Chaturvedi

Circulating tumor cells (CTCs) are crucial biomarkers in liquid biopsy, offering a noninvasive tool for cancer patient management. However, their identification remains particularly challenging due to their limited number and heterogeneity.…

Image and Video Processing · Electrical Eng. & Systems 2025-11-24 Martina Russo , Giulia Bertolini , Vera Cappelletti , Cinzia De Marco , Serena Di Cosimo , Petra Paiè , Nadia Brancati

Breast cancer remains a leading cause of cancer-related mortality worldwide, making early detection and accurate treatment response monitoring critical priorities. We present BreastDCEDL, a curated, deep learning-ready dataset comprising…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Naomi Fridman , Bubby Solway , Tomer Fridman , Itamar Barnea , Anat Goldstein

Accurate brain tumor segmentation from MRI is vital for diagnosis and treatment planning. Although Monte Carlo (MC) Dropout is widely used to estimate model uncertainty, the effectiveness of variance-based uncertainty - computed as…

Machine Learning · Computer Science 2026-05-28 Saumya B

Heterogeneity in characteristics from one region (sub-population) to another, commonly observed in complex systems, such as glasses and a collection of cells, is hard to describe theoretically. In the context of cancer, intra-tumor…

Soft Condensed Matter · Physics 2022-02-23 Sumit Sinha , Xin Li , Dave Thirumalai

In high-quality radiotherapy delivery, precise segmentation of targets and healthy structures is essential. This study proposes Radiomics features as a superior measure for assessing the segmentation ability of physicians and…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Yoichi Watanabe , Rukhsora Akramova

A definitive diagnosis of a brain tumour is essential for enhancing treatment success and patient survival. However, it is difficult to manually evaluate multiple magnetic resonance imaging (MRI) images generated in a clinic. Therefore,…

Neural and Evolutionary Computing · Computer Science 2022-04-27 Amin Abdollahi Dehkordi , Mina Hashemi , Mehdi Neshat , Seyedali Mirjalili , Ali Safaa Sadiq

Deep learning has shown tremendous progress in a wide range of digital pathology and medical image classification tasks. Its integration into safe clinical decision-making support requires robust and reliable models. However, real-world…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Abdur R. Fayjie , Jutika Borah , Florencia Carbone , Jan Tack , Patrick Vandewalle

Cancer is one of the leading causes of death globally, and early diagnosis is crucial for patient survival. Deep learning algorithms have great potential for automatic cancer analysis. Artificial intelligence has achieved high performance…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Monika Górka , Daniel Jaworek , Marek Wodzinski

Quantitative information on tumor heterogeneity and cell load could assist in designing effective and refined personalized treatment strategies. It was recently shown by us that such information can be inferred from the diffusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Yi Yin , Kai Breuhahn , Hans-Ulrich Kauczor , Oliver Sedlaczek , Irene E. Vignon-Clementel , Dirk Drasdo

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a minimally invasive imaging technique which can be used for characterizing tumor biology and tumor response to radiotherapy. Pharmacokinetic (PK) estimation is widely used…

Image and Video Processing · Electrical Eng. & Systems 2018-03-06 Xia Zhu , Dipanjan Sengupta , Andrew Beers , Kalpathy-Cramer Jayashree , Theodore L. Willke

The growth of many solid tumors has been found to be driven by chemo- and radiotherapy-resistant cancer stem cells (CSCs). A suitable therapeutic avenue in these cases may involve the use of a differentiating agent (DA) to force the…

Tissues and Organs · Quantitative Biology 2023-03-09 Jerónimo Fotinós , Lucas Barberis , Carlos A. Condat

Over the past decades, statisticians and machine-learning researchers have developed literally thousands of new tools for the reduction of high-dimensional data in order to identify the variables most responsible for a particular trait.…

Machine Learning · Statistics 2012-05-31 Chamont Wang , Jana Gevertz , Chaur-Chin Chen , Leonardo Auslender
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