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Personalized medicine is the future of medical practice. In oncology, tumor heterogeneity assessment represents a pivotal step for effective treatment planning and prognosis prediction. Despite new procedures for DNA sequencing and…

Multiparametric magnetic resonance imaging (mpMRI) is a key tool for assessing breast cancer progression. Although deep learning has been applied to automate tumor segmentation in breast MRI, the effect of sequence combinations in mpMRI…

Image and Video Processing · Electrical Eng. & Systems 2024-06-13 Hang Min , Gorane Santamaria Hormaechea , Prabhakar Ramachandran , Jason Dowling

Transformer models have demonstrated the capability to produce highly accurate segmentation of organs and tumors. However, model training requires high-quality curated datasets to ensure robust generalization to unseen datasets. Hence, we…

Accurate synthesis of a full 3D MR image containing tumours from available MRI (e.g. to replace an image that is currently unavailable or corrupted) would provide a clinician as well as downstream inference methods with important…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Raghav Mehta , Tal Arbel

Despite the promising performance of convolutional neural networks (CNNs) in brain tumor diagnosis from magnetic resonance imaging (MRI), their integration into the clinical workflow has been limited. That is mainly due to the fact that the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Sara Ketabi , Matthias W. Wagner , Cynthia Hawkins , Uri Tabori , Birgit Betina Ertl-Wagner , Farzad Khalvati

Uncontrolled cell division in the brain is what gives rise to brain tumors. If the tumor size increases by more than half, there is little hope for the patient's recovery. This emphasizes the need of rapid and precise brain tumor diagnosis.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Plabon Paul , Md. Nazmul Islam , Fazle Rafsani , Pegah Khorasani , Shovito Barua Soumma

Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC)…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ni Yao , Hang Hu , Kaicong Chen , Chen Zhao , Yuan Guo , Boya Li , Jiaofen Nan , Yanting Li , Chuang Han , Fubao Zhu , Weihua Zhou , Li Tian

Introduction: In sodium (23Na) magnetic resonance imaging (MRI), partial volume effects (PVE) are one of the most common causes of errors in the in vivo quantification of tissue sodium concentration (TSC). Advanced image reconstruction…

Effective treatment for rectal cancer relies on accurate lymph node metastasis (LNM) staging. However, radiological criteria based on lymph node (LN) size, shape and texture morphology have limited diagnostic accuracy. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2025-07-17 Benjamin Keel , Aaron Quyn , David Jayne , Maryam Mohsin , Samuel D. Relton

Brain tumors are abnormal cell growths in the central nervous system (CNS), and their timely detection is critical for improving patient outcomes. This paper proposes an automatic and efficient deep-learning framework for brain tumor…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ahta-Shamul Hoque Emran , Hafija Akter , Abdullah Al Shiam , Abu Saleh Musa Miah , Anichur Rahman , Fahmid Al Farid , Hezerul Abdul Karim

Early assessment of tumor therapeutic response is an important topic in precision medicine to optimize personalized treatment regimens and reduce unnecessary toxicity, cost, and delay. Although diffusion MRI (dMRI) has shown potential to…

Medical Physics · Physics 2024-08-06 Diwei Shi , Sisi Li , Fan Liu , Xiaoyu Jiang , Lei Wu , Li Chen , Quanshui Zheng , Haihua Bao , Hua Guo , Junzhong Xu

Breast cancer is the most diagnosed cancer in women, with HER2 status critically guiding treatment decisions. Noninvasive prediction of HER2 status from dynamic contrast-enhanced MRI (DCE-MRI) could streamline diagnostics and reduce…

Quantitative Methods · Quantitative Biology 2025-10-17 Naomi Fridman , Anat Goldstein

Volumetric images from Magnetic Resonance Imaging (MRI) provide invaluable information in preoperative staging of rectal cancer. Above all, accurate preoperative discrimination between T2 and T3 stages is arguably both the most challenging…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Joohyung Lee , Jieun Oh , Inkyu Shin , You-sung Kim , Dae Kyung Sohn , Tae-sung Kim , In So Kweon

Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Akshay Bhagwan Sonawane , Lena D. Swamikannan , Lakshman Tamil

Precise confidence estimation in deep learning is vital for high-stakes fields like medical imaging, where overconfident misclassifications can have serious consequences. This work evaluates the effectiveness of Temperature Scaling (TS), a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Ankur Chanda , Kushan Choudhury , Shubhrodeep Roy , Shubhajit Biswas , Somenath Kuiry

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

We present an algorithm for multi-scale tumor (chimeric cell) detection in high resolution slide scans. The broad range of tumor sizes in our dataset pose a challenge for current Convolutional Neural Networks (CNN) which often fail when…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Qingchao Zhang , Coy D. Heldermon , Corey Toler-Franklin

The diagnosis of brain tumours is an extremely sensitive and complex clinical task that must rely upon information gathered through non-invasive techniques. One such technique is magnetic resonance, in the modalities of imaging or…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 Carlos Arizmendi , Alfredo Vellido , Enrique Romero

Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Sevcan Turk , Kaya Oguz , Mehmet Orman , Emre Caliskan , Yesim Ertan , Erkin Ozgiray , Taner Akalin , Ashok Srinivasan , Omer Kitis

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu