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Synthetic data generation has been widely adopted in software testing, data privacy, imbalanced learning, and artificial intelligence explanation. In all such contexts, it is crucial to generate plausible data samples. A common assumption…

Artificial Intelligence · Computer Science 2024-10-16 Martina Cinquini , Fosca Giannotti , Riccardo Guidotti

Molecular dynamics (MD) simulations are essential tools in computational chemistry and drug discovery, offering crucial insights into dynamic molecular behavior. However, their utility is significantly limited by substantial computational…

Chemical Physics · Physics 2025-09-04 Bin Feng , Jiying Zhang , Xinni Zhang , Zijing Liu , Yu Li

Recent advances in deep learning have driven rapid progress in time series forecasting, yet many state-of-the-art models continue to struggle with robust performance in real-world applications, even when they achieve strong results on…

Machine Learning · Computer Science 2025-10-24 Qitai Tan , Yiyun Chen , Mo Li , Ruiwen Gu , Yilin Su , Xiao-Ping Zhang

Personalized computed tomography (CT) dosimetry has great potential in assessing patient-specific radiation exposure, supporting risk assessment, and optimizing clinical protocols. The aim of this study is to evaluate the potential of…

Medical Physics · Physics 2026-01-15 Marie-Luise Kuhlmann , Jörg Martin , Stefan Pojtinger

Many ground-breaking advancements in machine learning can be attributed to the availability of a large volume of rich data. Unfortunately, many large-scale datasets are highly sensitive, such as healthcare data, and are not widely available…

Machine Learning · Computer Science 2020-12-09 James Jordon , Alan Wilson , Mihaela van der Schaar

While synthetic tabular data generation using Deep Generative Models (DGMs) offers a compelling solution to data scarcity and privacy concerns, their effectiveness relies on the availability of substantial training data, often lacking in…

Machine Learning · Computer Science 2025-08-01 Patricia A. Apellániz , Ana Jiménez , Borja Arroyo Galende , Juan Parras , Santiago Zazo

Access to real-world healthcare data is limited by stringent privacy regulations and data imbalances, hindering advancements in research and clinical applications. Synthetic data presents a promising solution, yet existing methods often…

Machine Learning · Computer Science 2025-03-11 Nicholas I-Hsien Kuo , Blanca Gallego , Louisa Jorm

Major depressive disorder is a debilitating disease affecting 264 million people worldwide. While many antidepressant medications are available, few clinical guidelines support choosing among them. Decision support tools (DSTs) embodying…

Medical time-series data captures the dynamic progression of patient conditions, playing a vital role in modern clinical decision support systems. However, real-world clinical data is highly heterogeneous and inconsistently formatted.…

Machine Learning · Computer Science 2026-04-01 Zhongheng Jiang , Yuechao Zhao , Donglin Xie , Chenxi Sun , Rongchen Lu , Silu Luo , Zisheng Liang , Shenda Hong

Modern studies of societal phenomena rely on the availability of large datasets capturing attributes and activities of synthetic, city-level, populations. For instance, in epidemiology, synthetic population datasets are necessary to study…

Databases · Computer Science 2016-02-26 Hao Wu , Yue Ning , Prithwish Chakraborty , Jilles Vreeken , Nikolaj Tatti , Naren Ramakrishnan

The potential of synthetic data to replace real data creates a huge demand for synthetic data in data-hungry AI. This potential is even greater when synthetic data is used for training along with a small number of real images from domains…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Hyungtae Lee , Yan Zhang , Heesung Kwon , Shuvra S. Bhattacharrya

One major barrier to advancing aerial autonomy has been collecting large-scale aerial datasets for training machine learning models. Due to costly and time-consuming real-world data collection through deploying drones, there has been an…

Computer Vision and Pattern Recognition · Computer Science 2023-05-29 Mehrnaz Sabet , Praveen Palanisamy , Sakshi Mishra

A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which…

The adoption of machine learning (ML) and, more specifically, deep learning (DL) applications into all major areas of our lives is underway. The development of trustworthy AI is especially important in medicine due to the large implications…

Machine Learning · Computer Science 2024-02-22 Daniel Schwabe , Katinka Becker , Martin Seyferth , Andreas Klaß , Tobias Schäffter

Advances in genomic medicine accelerate the identi cation of mutations in disease-associated genes, but the pathogenicity of many mutations remains unknown, hindering their use in diagnostics and clinical decision-making. Predictive AI…

Recent smaller language models such Phi-3.5 and Phi-4 rely on synthetic data generated using larger Language models. Questions remain about leveraging synthetic data for other use cases, such as adapting LLMs to specific domains. A key…

Computation and Language · Computer Science 2025-11-06 Haris Riaz , Sourav Bhabesh , Vinayak Arannil , Miguel Ballesteros , Graham Horwood

The global need for effective disease diagnosis remains substantial, given the complexities of various disease mechanisms and diverse patient symptoms. To tackle these challenges, researchers, physicians, and patients are turning to machine…

Machine Learning · Computer Science 2023-10-27 S M Atikur Rahman , Sifat Ibtisum , Ehsan Bazgir , Tumpa Barai

Since decades, the modelling of metadata has been core to the functioning of any academic library. Its importance has only enhanced with the increasing pervasiveness of Generative Artificial Intelligence (AI)-driven information activities…

Digital Libraries · Computer Science 2025-03-18 Mayukh Bagchi

In recent years, AI-assisted IC design methods have demonstrated great potential, but the availability of circuit design data is extremely limited, especially in the public domain. The lack of circuit data has become the primary bottleneck…

Machine Learning · Computer Science 2025-09-03 Shang Liu , Jing Wang , Wenji Fang , Zhiyao Xie

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso