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Insufficient amounts of available training data is a critical challenge for both development and deployment of artificial intelligence and machine learning (AI/ML) models. This paper proposes a unified approach to both synthetic data…

Machine Learning · Computer Science 2025-05-20 Alice Williams , Boris Kovalerchuk

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

Synthetic data has emerged as a powerful resource in life sciences, offering solutions for data scarcity, privacy protection and accessibility constraints. By creating artificial datasets that mirror the characteristics of real data, allows…

The generation of synthetic clinical trial data offers a promising approach to mitigating privacy concerns and data accessibility limitations in medical research. However, ensuring that synthetic datasets maintain high fidelity, utility,…

Machine Learning · Computer Science 2025-12-16 Waldemar Hahn , Jan-Niklas Eckardt , Christoph Röllig , Martin Sedlmayr , Jan Moritz Middeke , Markus Wolfien

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…

Cryptography and Security · Computer Science 2022-11-22 Florimond Houssiau , Samuel N. Cohen , Lukasz Szpruch , Owen Daniel , Michaela G. Lawrence , Robin Mitra , Henry Wilde , Callum Mole

Synthetic data generation has proven to be a promising solution for addressing data availability issues in various domains. Even more challenging is the generation of synthetic time series data, where one has to preserve temporal dynamics,…

Quantum Physics · Physics 2022-04-14 Haim Horowitz , Pooja Rao , Santosh Kumar Radha

The digital transformation of modern cities by integrating advanced information, communication, and computing technologies has marked the epoch of data-driven smart city applications for efficient and sustainable urban management. Despite…

Artificial Intelligence · Computer Science 2024-08-08 Haowen Xu , Femi Omitaomu , Soheil Sabri , Sisi Zlatanova , Xiao Li , Yongze Song

Synthetic Data Generation (SDG), leveraging Large Language Models (LLMs), has recently been recognized and broadly adopted as an effective approach to improve the performance of smaller but more resource and compute efficient LLMs through…

Machine Learning · Computer Science 2026-03-25 Srideepika Jayaraman , Achille Fokoue , Dhaval Patel , Jayant Kalagnanam

The role of AI-generated synthetic data has recently been expanded to support realistic Monte Carlo simulations. However, guidance is limited on generating data with multilevel structures and designing simulations based on such data. This…

Methodology · Statistics 2026-05-08 Youmi Suk , Chenguang Pan , Weixuan Xiao

This paper presents SYMBIOSIS, an AI-powered framework and platform designed to make Systems Thinking accessible for addressing societal challenges and unlock paths for leveraging systems thinking frameworks to improve AI systems. The…

Computers and Society · Computer Science 2025-03-11 Sameer Sethi , Donald Martin , Emmanuel Klu

The Cloud paradigm is at a critical point in which the existing energy-efficiency techniques are reaching a plateau, while the computing resources demand at Data Center facilities continues to increase exponentially. The main challenge in…

Machine Learning · Computer Science 2023-06-19 Jaime Pérez , Patricia Arroba , José M. Moya

Data scarcity remains a significant challenge in the field of emotion recognition using physiological signals, as acquiring comprehensive and diverse datasets is often prevented by privacy concerns and logistical constraints. This…

Neural and Evolutionary Computing · Computer Science 2025-01-29 S. Muhammad Hossein Mousavi

The use of synthetic data to deidentify data and to improve predictive models is well-attested to. The augmentation of datasets using synthetically generated data is an alluring proposition: in the best case, it generates realistic data…

Methodology · Statistics 2026-03-20 Reid Dale , Jordan Rodu , Mike Baiocchi

Single-arm trials are an important study design for evaluating drug efficacy and safety without enrolling patients into a control arm. Although they do not provide the gold-standard evidence of randomized controlled trials, they are…

Applications · Statistics 2026-05-14 Daniele Bertolini , Franklin Fuller , Aaron M. Smith , Jonathan R. Walsh , Run Zhuang

The purpose of this study is to investigate the development process for Artificial inelegance (AI) and machine learning (ML) applications in order to provide the best support environment. The main stages of ML are problem understanding,…

Software Engineering · Computer Science 2023-08-16 Taha Khamis , Hamam Mokayed

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

Generative Artificial Intelligence (AI) technologies and large models are producing realistic outputs across various domains, such as images, text, speech, and music. Creating these advanced generative models requires significant resources,…

AI models present a wide range of applications in the field of medicine. However, achieving optimal performance requires access to extensive healthcare data, which is often not readily available. Furthermore, the imperative to preserve…

Over the past decades, cognitive neuroscientists and behavioral economists have recognized the value of describing the process of decision making in detail and modeling the emergence of decisions over time. For example, the time it takes to…

Neurons and Cognition · Quantitative Biology 2025-07-24 Mrugsen Nagsen Gopnarayan , Jaan Aru , Sebastian Gluth

Enhancing the ability of Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs) to interpret sheet music is a crucial step toward building AI musicians. However, current research lacks both evaluation benchmarks and…

Computation and Language · Computer Science 2025-09-29 Zhilin Wang , Zhe Yang , Yun Luo , Yafu Li , Xiaoye Qu , Ziqian Qiao , Haoran Zhang , Runzhe Zhan , Derek F. Wong , Jizhe Zhou , Yu Cheng