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While interest in the application of generative AI (GenAI) in network optimization has surged in recent years, its rapid progress has often overshadowed critical limitations intrinsic to generative models that remain insufficiently examined…

Networking and Internet Architecture · Computer Science 2026-01-15 Bo Yang , Ruihuai Liang , Weixin Li , Han Wang , Xuelin Cao , Zhiwen Yu , Samson Lasaulce , Mérouane Debbah , Mohamed-Slim Alouini , H. Vincent Poor , Chau Yuen

Modern language model-based AI systems are remarkably powerful, yet their capabilities remain fundamentally capped by their human creators in three key ways. First, although a model's weights can be updated via fine-tuning, acquiring new…

Artificial Intelligence · Computer Science 2026-03-20 Zitong Yang

Synthetic Data is not new, but recent advances in Generative AI have raised interest in expanding the research toolbox, creating new opportunities and risks. This article provides a taxonomy of the full breadth of the Synthetic Data domain.…

Human-Computer Interaction · Computer Science 2024-08-29 Richard Timpone , Yongwei Yang

Clinical time series data from electronic health records and medical registries offer unprecedented opportunities to understand patient trajectories and inform medical decision-making. However, leveraging such data presents significant…

Machine Learning · Computer Science 2025-11-21 Muhammad Aslanimoghanloo , Ahmed ElGazzar , Marcel van Gerven

$\textbf{Background:}$ At the onset of a pandemic, such as COVID-19, data with proper labeling/attributes corresponding to the new disease might be unavailable or sparse. Machine Learning (ML) models trained with the available data, which…

Domain-aware machine learning (ML) models have been increasingly adopted for accelerating small molecule therapeutic design in the recent years. These models have been enabled by significant advancement in state-of-the-art artificial…

Machine Learning · Computer Science 2021-02-12 Rajendra P. Joshi , Neeraj Kumar

AI-based persona simulation -- often referred to as digital twin simulation -- is increasingly used for market research, recommender systems, and social sciences. Despite their flexibility, large language models (LLMs) often exhibit…

Machine Learning · Computer Science 2026-04-10 Grace Jiarui Fan , Chengpiao Huang , Tianyi Peng , Kaizheng Wang , Yuhang Wu

The role of Artificial Intelligence (AI) is growing in every stage of drug development. Nevertheless, a major challenge in drug discovery AI remains: Drug pharmacokinetic (PK) and Drug-Target Interaction (DTI) datasets collected in…

Quantitative Methods · Quantitative Biology 2025-10-27 Bing Hu , Jong-Hoon Park , Helen Chen , Young-Rae Cho , Anita Layton

Generating molecular dynamics (MD) trajectories using deep generative models has attracted increasing attention, yet remains inherently challenging due to the limited availability of MD data and the complexities involved in modeling…

Machine Learning · Computer Science 2026-04-07 Aniketh Iyengar , Jiaqi Han , Pengwei Sun , Mingjian Jiang , Jianwen Xie , Stefano Ermon

Generative AI systems are increasingly used by patients seeking everyday health guidance, yet their appropriateness in chronic care contexts remains unclear. Focusing on Type 2 Diabetes Mellitus (T2DM), this paper presents a mixed-methods…

Human-Computer Interaction · Computer Science 2026-01-06 Yibo Meng , Ruiqi Chen , Bingyi Liu , Yan Guan , Xiaolan Ding

Among the biggest challenges we face in utilizing neural networks trained on waveform data (i.e., seismic, electromagnetic, or ultrasound) is its application to real data. The requirement for accurate labels forces us to develop solutions…

Geophysics · Physics 2021-09-14 Tariq Alkhalifah , Hanchen Wang , Oleg Ovcharenko

Optimizing credit limits, interest rates, and loan terms is crucial for managing borrower risk and lifetime value (LTV) in personal loan platform. However, counterfactual estimation of these continuous, multi-dimensional treatments faces…

Machine Learning · Computer Science 2025-08-12 Kexin Zhao , Bo Wang , Cuiying Zhao , Tongyao Wan

Synthetic data generation (SDG) is a promising approach for enabling data sharing in biomedical studies while preserving patient privacy. Yet, state-of-the-art generative models often require large datasets and complex training procedures,…

Machine Learning · Computer Science 2026-01-27 Natalia Espinosa-Dice , Nicholas J. Jackson , Chao Yan , Aaron Lee , Bradley A. Malin

Industrial process optimization and control is crucial to increase economic and ecologic efficiency. However, data sovereignty, differing goals, or the required expert knowledge for implementation impede holistic implementation. Further,…

Machine Learning · Computer Science 2024-08-28 Johannes Emmert , Ronald Mendez , Houman Mirzaalian Dastjerdi , Christopher Syben , Andreas Maier

Synthetic data has emerged as a cost-effective alternative to real data for training artificial neural networks (ANN). However, the disparity between synthetic and real data results in a domain gap. That gap leads to poor performance and…

Machine Learning · Computer Science 2025-09-03 Paul Wachter , Lukas Niehaus , Julius Schöning

Generative AI has seen remarkable growth over the past few years, with diffusion models being state-of-the-art for image generation. This study investigates the use of diffusion models in generating artificial data generation for electronic…

Machine Learning · Computer Science 2023-10-18 Prasha Srivastava , Pawan Kumar , Zia Abbas

We provide new algorithms for two tasks relating to heterogeneous tabular datasets: clustering, and synthetic data generation. Tabular datasets typically consist of heterogeneous data types (numerical, ordinal, categorical) in columns, but…

Machine Learning · Computer Science 2024-04-22 Chandrani Kumari , Rahul Siddharthan

Physician-physician discussions of patient cases represent a rich source of clinical knowledge and reasoning that could feed AI agents to enrich and even participate in subsequent interactions. However, privacy regulations and ethical…

Computation and Language · Computer Science 2026-04-13 Beny Rubinstein , Sergio Matos

We consider the problem of synthetically generating data that can closely resemble human decisions made in the context of an interactive human-AI system like a computer game. We propose a novel algorithm that can generate synthetic,…

Machine Learning · Computer Science 2023-04-17 Bryan Brandt , Prithviraj Dasgupta

The growing number of pretrained models in Machine Learning (ML) presents significant challenges for practitioners. Given a new dataset, they need to determine the most suitable deep learning (DL) pipeline, consisting of the pretrained…

Machine Learning · Computer Science 2025-06-17 Fabio Ferreira
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