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Cellular differentiation is governed by gene regulatory networks, the high-dimensional stochastic biochemical systems that determine the transcriptional landscape and mediate cellular responses to signals and perturbations. Although…

Molecular Networks · Quantitative Biology 2026-04-29 Suryanarayana Maddu , Victor Chardès , Michael J. Shelley

Our knowledge of how individual cells self-organize to form complex multicellular systems is being revolutionized by a data outburst, coming from high-throughput experimental breakthroughs such as single-cell RNA sequencing and spatially…

Cell Behavior · Quantitative Biology 2021-04-20 Gabriel Torregrosa , Jordi Garcia-Ojalvo

Identifying genes that display spatial patterns is critical to investigating expression interactions within a spatial context and further dissecting biological understanding of complex mechanistic functionality. Despite the increase in…

Methodology · Statistics 2025-10-06 Mingcong Wu , Yang Li , Shuangge Ma , Mengyun Wu

Single-cell RNA sequencing (scRNA-seq) is powerful technology that allows researchers to understand gene expression patterns at the single-cell level. However, analysing scRNA-seq data is challenging due to issues and biases in data…

Genomics · Quantitative Biology 2023-12-14 Jinlu Liu , Sara Wade , Natalia Bochkina

Spatial transcriptomics (ST) technologies can be used to align transcriptomes with histopathological morphology, presenting exciting new opportunities for biomolecular discovery. Using ST data, we construct a novel framework, GeneFlow, to…

Quantitative Methods · Quantitative Biology 2025-11-04 Mengbo Wang , Shourya Verma , Aditya Malusare , Luopin Wang , Yiyang Lu , Vaneet Aggarwal , Mario Sola , Ananth Grama , Nadia Atallah Lanman

The application of deep learning to 3D point clouds is challenging due to its lack of order. Inspired by the point embeddings of PointNet and the edge embeddings of DGCNNs, we propose three improvements to the task of point cloud analysis.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Chaitanya Kaul , Nick Pears , Suresh Manandhar

Single-shot volumetric fluorescence (SVF) imaging offers a significant advantage over traditional imaging methods that require scanning across multiple axial planes as it can capture biological processes with high temporal resolution. The…

Spatial transcriptomics is a modern sequencing technology that allows the measurement of the activity of thousands of genes in a tissue sample and map where the activity is occurring. This technology has enabled the study of the so-called…

Methodology · Statistics 2022-09-15 Andrea Sottosanti , Davide Risso

As 3D point clouds become the representation of choice for multiple vision and graphics applications, the ability to synthesize or reconstruct high-resolution, high-fidelity point clouds becomes crucial. Despite the recent success of deep…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guandao Yang , Xun Huang , Zekun Hao , Ming-Yu Liu , Serge Belongie , Bharath Hariharan

In this paper, we propose a simple yet effective method to represent point clouds as sets of samples drawn from a cloud-specific probability distribution. This interpretation matches intrinsic characteristics of point clouds: the number of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Michał Stypułkowski , Kacper Kania , Maciej Zamorski , Maciej Zięba , Tomasz Trzciński , Jan Chorowski

LiDAR point cloud semantic segmentation enables the robots to obtain fine-grained semantic information of the surrounding environment. Recently, many works project the point cloud onto the 2D image and adopt the 2D Convolutional Neural…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Yu Zheng , Guangming Wang , Jiuming Liu , Marc Pollefeys , Hesheng Wang

We propose hybrid methods for localization in wireless sensor networks fusing noisy range measurements with angular information (extracted from video). Compared with conventional methods that rely on a single sensed variable, this may pave…

Optimization and Control · Mathematics 2018-01-26 Beatriz Quintino Ferreira , João Gomes , Cláudia Soares , João P. Costeira

We consider the problem of embedding point cloud data sampled from an underlying manifold with an associated flow or velocity. Such data arises in many contexts where static snapshots of dynamic entities are measured, including in…

Modern high-throughput single-cell immune profiling technologies, such as flow and mass cytometry and single-cell RNA sequencing can readily measure the expression of a large number of protein or gene features across the millions of cells…

Quantitative Methods · Quantitative Biology 2022-07-05 Vishal Athreya Baskaran , Jolene Ranek , Siyuan Shan , Natalie Stanley , Junier B. Oliva

Single-Cell RNA sequencing (scRNA-seq) measurements have facilitated genome-scale transcriptomic profiling of individual cells, with the hope of deconvolving cellular dynamic changes in corresponding cell sub-populations to better…

Genomics · Quantitative Biology 2021-04-06 Seyednami Niyakan , Ehsan Hajiramezanali , Shahin Boluki , Siamak Zamani Dadaneh , Xiaoning Qian

Traditional ship detection methods primarily rely on single-modal approaches, such as visible or infrared images, which limit their application in complex scenarios involving varying lighting conditions and heavy fog. To address this issue,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Yanyin Guo , Runxuan An , Junwei Li , Zhiyuan Zhang

Localization of single fluorescent molecules is key for physicochemical and biophysical measurements such as single-molecule tracking and super-resolution imaging by single-molecule localization microscopy (SMLM). Recently a series of…

Optics · Physics 2021-09-06 Luciano A. Masullo , Lucía F. Lopez , Fernando D. Stefani

Although data diffusion embeddings are ubiquitous in unsupervised learning and have proven to be a viable technique for uncovering the underlying intrinsic geometry of data, diffusion embeddings are inherently limited due to their discrete…

Computer Vision and Pattern Recognition · Computer Science 2023-06-13 Oluwadamilola Fasina , Guillaume Huguet , Alexander Tong , Yanlei Zhang , Guy Wolf , Maximilian Nickel , Ian Adelstein , Smita Krishnaswamy

Modern agricultural applications rely more and more on deep learning solutions. However, training well-performing deep networks requires a large amount of annotated data that may not be available and in the case of 3D annotation may not…

Computer Vision and Pattern Recognition · Computer Science 2024-04-19 George Retsinas , Niki Efthymiou , Petros Maragos

Registration of diffusion MRI tractography is an essential step for analyzing group similarities and variations in the brain's white matter (WM). Streamline-based registration approaches can leverage the 3D geometric information of fiber…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Junyi Wang , Mubai Du , Ye Wu , Yijie Li , William M. Wells , Lauren J. O'Donnell , Fan Zhang
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