Related papers: Pulse Parameter Optimization Method for Ultra High…
Purpose: Highlight the distinctions, both in terms of concept and numerical values, of the various definitions that can be established for the dose rate in PBS proton therapy. Methods: In an in silico study, five definitions of the dose…
To accurately verify the dose of intensity-modulated radiation therapy (IMRT), we have used a global optimization method to investigate a new dose-verification algorithm. In practical application of this quality assurance (QA) procedure,…
A central aspect of every pulsed radar signal processor is the targets Range-Doppler estimation within a Coherent Processing Interval. Conventional methods typically rely on simplifying assumptions, such as linear target motion, narrowband…
Objective: While FLASH radiotherapy is recognized for short-term normal tissue sparing, its durability in late-responding organs remains uncertain, limiting clinical adoption. With its clinical importance and steep dose-response, the spinal…
As data transmission demands grow, long-haul optical transmission links face increasing pressure to increase their throughput. Expanding usable bandwidth through Ultra-Wide Band (UWB) systems has become the primary strategy for increasing…
The advent of ultra-high dose rate irradiation, known as FLASH radiation therapy, has shown promising potential in reducing toxicity while maintaining tumor control. However, the clinical translation of these benefits necessitates efficient…
In this paper, we numerically optimize broadband pulse shapes that maximize Hahn echo amplitudes. Pulses are parameterized as neural networks (NN), nonlinear amplitude limited Fourier series (FS), and discrete time series (DT). These are…
The generation of optical pulses at ultra low bias level, thus low energy cost, is explored in a commercial microcavity semiconductor laser in view of testing the principle of energy efficient information encoding in potential integrated…
This dissertation explores the interaction between high-intensity lasers and plasmas to accelerate electrons and produce radiation via experimental and computational efforts. The laser pulses used in this dissertation have ultrashort…
Efficient quantum control is necessary for practical quantum computing implementations with current technologies. Conventional algorithms for determining optimal control parameters are computationally expensive, largely excluding them from…
The potential of the Dense Plasma Focus (DPF) for industrial applications in many fields is well recognized, although yet to be realized in practice. Particularly attractive is the possibility of its use as inexpensive industrial source of…
We demonstrate a remarkably effective single-stage compression technique for ultrafast pulses in the visible electromagnetic spectrum using second-harmonic pulses at 515 nmderived from a 1030 nm Yb-based femtosecond regenerative amplifier.…
We present the development of a high power fibre laser system to investigate its suitability for use in a transverse electron beam profile monitor i.e. a laserwire. A system capable of producing individual pulses up to $165.8 \pm 0.4 \mu$J…
We describe how active feedback routines can be applied at limited repetition rate (5 Hz) to optimize high-power $>10$ TW) laser interactions with clustered gases. Optimization of x-ray production from an argon cluster jet, using a genetic…
Plasma surface high-order harmonics generation (SHHG) driven by intense laser pulses on plasma targets enables a high-quality extreme ultraviolet source with high pulse energy and outstanding spatiotemporal coherence. Optimizing the…
We optimize the pulse shape and polarization of time-dependent electric fields to maximize the production of electron-positron pairs via strong field quantum electrodynamics processes. The pulse is parametrized in Fourier space by a…
Recent studies have demonstrated the possibility of accelerating electrons to MeV energies in ambient air using tightly focused laser configurations. In this article, we explore possible strategies to control and optimize the resulting…
Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…
Ultrafast pulses, particularly those with durations under 100 femtoseconds, are crucial in achieving unprecedented precision and control in light-matter interactions. However, conventional on-chip photonic platforms are not inherently…
We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…