Related papers: Pulse Parameter Optimization Method for Ultra High…
We introduce a filter-construction method for pulse processing that differs in two respects from that in standard optimal filtering, in which the average pulse shape and noise-power spectral density are combined to create a convolution…
Laser-driven proton sources have long been developed with an eye on their potential for medical application to radiation therapy. These sources are compact, versatile, and show peculiar characteristics such as extreme instantaneous dose…
Background: Ultra-high dose rate proton therapy shows promise in tissue sparing by enhancing therapeutic ratio through the FLASH effect. In radiotherapy, accurate in vivo dosimetry is crucial for quality assurance, but remains challenging…
Achieving high-performance perovskite photovoltaics, especially in ambient air relies heavily on optimizing process parameters. However, traditional manual methods often struggle to effectively control the key variables. This inherent…
High-order harmonic generation (HHG) in gases has been studied for almost 40 years in many different conditions, varying the laser wavelength, intensity, focusing geometry, target design, gas species, etc. However, no systematic…
Radiation chemistry of model systems irradiated with ultra-high dose-rates (UHDR) is key to obtain a mechanistic understanding of the sparing of healthy tissue, which is called the FLASH effect. It is envisioned to be used for efficient…
Purpose: Ultra-fast scintillation imaging has been shown to provide a unique tool for spatio-temporal dosimetry of conventional cyclotron and synchrocyclotron pencil beam scanning (PBS) deliveries, indicating the potential use for…
FLASH radiotherapy necessitates the development of advanced Quality Assurance methods and detectors for accurate and online monitoring of the radiation field. This study introduces enhanced time-resolution detection systems and methods…
With an increase in the application of ultra-wideband (UWB) electromagnetic pulses in the communications industry, radar, biotechnology and medicine, comes an interest in UWB exposure safety standards. Despite an increase of the scientific…
Background: Ultra-high-dose-rate (UHDR) radiation therapy has demonstrated promising potential in reducing toxicity to organs-at-risk (OARs). Proton therapy is uniquely positioned to deliver UHDR by leveraging the Bragg peak in conjunction…
For many applications of pulsed radiation, the time-history of the radiation intensity must be optimized to induce a desired time-history of conditions. This optimization is normally performed using multi-physics simulations of the system.…
We present some approaches to the computation of ultra-fast laser pulses capable of selectively breaking molecular bonds. The calculations are based on a mixed quantum-classical description: The electrons are treated quantum mechanically…
FLASH is a new treatment modality that requires optimization of dose, dose rate, and LET. Here we validate these three quantities under FLASH conditions, which includes the quantum uncertainty in the time-dependent instantaneous dose rate…
We report our investigation on ultrashort laser pulse optimization using an AI algorithm in a system consisting of a mode-locked oscillator, a spectral phase shaper, and a highly nonlinear amplifier. We analyzed the performance of the pulse…
High harmonic generation (HHG) is a crucial technology for compact, high-brightness extreme ultraviolet (XUV) and soft X-ray sources, which are key to advancing both fundamental and applied sciences. The availability of advanced driving…
The future applications of the short-duration, multi-MeV ion beams produced in the interaction of high-intensity laser pulses with solid targets will require improvements in the conversion efficiency, peak ion energy, beam monochromaticity,…
We present a detailed numerical study of ultrashort pulse compression using a three-stage hybrid all-bulk multipass cell scheme. By operating in the enhanced frequency chirp regime, we achieve the compression of pulses from around 180 fs to…
In this study, a novel method for simulating plasma dynamics using parallel programming has been developed. The equations based on Particle-in-Cell (PIC) method were utilized and adapted for this purpose. We utilized 35 processors from…
Objective: In this study, a fast imaging technique was developed for the first in vivo Cherenkov emission imaging from an ultra-high dose rate (UHDR) electron beam source at single pulse (360 Hz) submillimeter resolution. Approach: A CMOS…
We propose and detail a multi-step analytical procedure, based on an improved fully relativistic plane model for Laser Wake Field Acceleration, to tailor the initial density of a cold diluted plasma to the laser pulse profile, so as to…