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Multi-sequence MRI is valuable in clinical settings for reliable diagnosis and treatment prognosis, but some sequences may be unusable or missing for various reasons. To address this issue, MRI synthesis is a potential solution. Recent deep…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Luyi Han , Tianyu Zhang , Yunzhi Huang , Haoran Dou , Xin Wang , Yuan Gao , Chunyao Lu , Tan Tao , Ritse Mann

Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Benjamin Towle , Xin Chen , Ke Zhou

Three-dimensional (3D) medical images, such as Computed Tomography (CT) and Magnetic Resonance Imaging (MRI), are essential for clinical applications. However, the need for diverse and comprehensive representations is particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Siwen Wang , Churan Wang , Fei Gao , Lixian Su , Fandong Zhang , Yizhou Wang , Yizhou Yu

Designing novel protein sequences for a desired 3D topological fold is a fundamental yet non-trivial task in protein engineering. Challenges exist due to the complex sequence--fold relationship, as well as the difficulties to capture the…

Machine Learning · Computer Science 2021-06-25 Yue Cao , Payel Das , Vijil Chenthamarakshan , Pin-Yu Chen , Igor Melnyk , Yang Shen

In many real-world applications, modeling both the internal structure of sets and their temporal relationships is essential for capturing complex underlying patterns. Sequential multiple-instance learning aims to address this challenge by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Athanasios Efthymiou , Stevan Rudinac , Monika Kackovic , Nachoem Wijnberg , Marcel Worring

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

In this work, we investigate unsupervised representation learning on medical time series, which bears the promise of leveraging copious amounts of existing unlabeled data in order to eventually assist clinical decision making. By evaluating…

Machine Learning · Computer Science 2018-12-04 Xinrui Lyu , Matthias Hueser , Stephanie L. Hyland , George Zerveas , Gunnar Raetsch

Self-supervised deep learning has accelerated 2D natural image analysis but remains difficult to translate into 3D MRI, where data are scarce and pre-trained 2D backbones cannot capture volumetric context. We present a…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

Foundation models have become a promising paradigm for advancing medical image analysis, particularly for segmentation tasks where downstream applications often emerge sequentially. Existing fine-tuning strategies, however, remain limited:…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Yiwen Ye , Yicheng Wu , Xiangde Luo , He Zhang , Ziyang Chen , Ting Dang , Yanning Zhang , Yong Xia

Purpose: Different Magnetic resonance imaging (MRI) modalities of the same anatomical structure are required to present different pathological information from the physical level for diagnostic needs. However, it is often difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-09-15 Yuchen Fei , Bo Zhan , Mei Hong , Xi Wu , Jiliu Zhou , Yan Wang

Purpose: The aim of this work is to develop a neural network training framework for continual training of small amounts of medical imaging data and create heuristics to assess training in the absence of a hold-out validation or test set.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Sohaib Naim , Brian Caffo , Haris I Sair , Craig K Jones

The rise of In-Context Learning (ICL) for universal medical image segmentation has introduced an unprecedented demand for large-scale, diverse datasets for training, exacerbating the long-standing problem of data scarcity. While data…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Chenfei Ye , Hanyang Peng , Jianfeng Cao , Ting Ma

As acquiring MRIs is expensive, neuroscience studies struggle to attain a sufficient number of them for properly training deep learning models. This challenge could be reduced by MRI synthesis, for which Generative Adversarial Networks…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Wei Peng , Ehsan Adeli , Tomas Bosschieter , Sang Hyun Park , Qingyu Zhao , Kilian M. Pohl

Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Jee Seok Yoon , Chenghao Zhang , Heung-Il Suk , Jia Guo , Xiaoxiao Li

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Insufficiency of training data is a persistent issue in medical image analysis, especially for task-based functional magnetic resonance images (fMRI) with spatio-temporal imaging data acquired using specific cognitive tasks. In this paper,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Jiyao Wang , Nicha C. Dvornek , Lawrence H. Staib , James S. Duncan

Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Lijun Yan , Churan Wang , Fangwei Zhong , Yizhou Wang

Representation learning is an important step in the machine learning pipeline. Given the current biological sequencing data volume, learning an explicit representation is prohibitive due to the dimensionality of the resulting feature…

Machine Learning · Computer Science 2023-04-04 Sarwan Ali , Usama Sardar , Murray Patterson , Imdad Ullah Khan

Generative AI models hold great potential in creating synthetic brain MRIs that advance neuroimaging studies by, for example, enriching data diversity. However, the mainstay of AI research only focuses on optimizing the visual quality (such…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Wei Peng , Tomas Bosschieter , Jiahong Ouyang , Robert Paul , Ehsan Adeli , Qingyu Zhao , Kilian M. Pohl

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels
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