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To mitigate the spread of COVID-19 pandemic, decision-makers and public authorities have announced various non-pharmaceutical policies. Analyzing the causal impact of these policies in reducing the spread of COVID-19 is important for future…

Machine Learning · Computer Science 2021-06-03 Jing Ma , Yushun Dong , Zheng Huang , Daniel Mietchen , Jundong Li

We propose an epidemiological model that includes the mobility patterns of the individuals, in the spirit to those considered in (Barmak, 2011, 2016) and (Medus, 2011). We assume that people move around in a city of 120x120 blocks with 300…

Physics and Society · Physics 2021-12-08 Fernando E. Cornes , Guillermo A. Frank , Claudio O. Dorso

Some patients with COVID-19 show changes in signs and symptoms such as temperature and oxygen saturation days before being positively tested for SARS-CoV-2, while others remain asymptomatic. It is important to identify these subgroups and…

Methodology · Statistics 2024-10-22 Xiaoran Ma , Wensheng Guo , Mengyang Gu , Len Usvyat , Peter Kotanko , Yuedong Wang

One fundamental statistical question for research areas such as precision medicine and health disparity is about discovering effect modification of treatment or exposure by observed covariates. We propose a semiparametric framework for…

Methodology · Statistics 2020-08-04 Muxuan Liang , Menggang Yu

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

I employ a simple mathematical model of an epidemic process to evaluate how four basic quantities: the reproduction number (R), the numbers of sensitive (S) and infectious individuals(I), and total community size (N) affect strategies to…

Populations and Evolution · Quantitative Biology 2020-05-08 Michael E. Hochberg

Recently, the world has witnessed the most severe pandemic (COVID-19) in this century. Studies on epidemic prediction and simulation have received increasing attention. However, the current methods suffer from three issues. First, most of…

Social and Information Networks · Computer Science 2023-03-31 Haoyu Geng , Guanjie Zheng , Zhengqing Han , Hua Wei , Zhenhui Li

This paper introduces non-linear dimension reduction in factor-augmented vector autoregressions to analyze the effects of different economic shocks. I argue that controlling for non-linearities between a large-dimensional dataset and the…

Econometrics · Economics 2023-09-12 Karin Klieber

Marginal structural models are a popular method for estimating causal effects in the presence of time-varying exposures. In spite of their popularity, no scalable non-parametric estimator exist for marginal structural models with…

Methodology · Statistics 2024-09-30 Axel Martin , Michele Santacatterina , Iván Díaz

Motivated by the ongoing pandemic COVID-19, we propose a closed-loop framework that combines inference from testing data, learning the parameters of the dynamics and optimal resource allocation for controlling the spread of the…

Physics and Society · Physics 2021-04-27 Ashish R. Hota , Jaydeep Godbole , Philip E Paré

We create a network model to study the spread of an epidemic through physically proximate and accidental daily human contacts in a city, and simulate outcomes for two kinds of agents - poor and non-poor. Under non-intervention, peak…

Physics and Society · Physics 2021-01-27 Anand Sahasranaman , Henrik Jeldtoft Jensen

We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…

Optimization and Control · Mathematics 2021-06-29 David I. Ketcheson

During outbreaks of emerging infectious diseases, internationally connected cities often experience large and early outbreaks, while rural regions follow after some delay. This hierarchical structure of disease spread is influenced…

Epidemics of infectious diseases are among the largest threats to the quality of life and the economic and social well-being of developing countries. The arsenal of measures against such epidemics is well-established, but costly and…

Social and Information Networks · Computer Science 2013-07-09 Mohamed Kafsi , Ehsan Kazemi , Lucas Maystre , Lyudmila Yartseva , Matthias Grossglauser , Patrick Thiran

Recent outbreak of the novel coronavirus COVID-19 has affected all of our lives in one way or the other. While medical researchers are working hard to find a cure and doctors/nurses to attend the affected individuals, measures such as…

Methodology · Statistics 2020-07-23 Arkaprava Roy , Sayar Karmakar

Non-pharmacologic interventions (NPIs) are one method to mitigate the spread and effects of the COVID-19 pandemic in the United States. NPIs promote protective actions to reduce exposure risk and can reduce mobility patterns within…

Physics and Society · Physics 2021-07-16 Natalie Coleman , Xinyu Gao , Jared DeLeon , Ali Mostafavi

The COVID-19 pandemic underscored a critical need for intervention strategies that balance disease containment with socioeconomic stability. We approach this challenge by designing a framework for modeling and evaluating disease-spread…

Machine Learning · Computer Science 2025-10-07 Marian Chen , Miri Zilka

Countries around the world implement nonpharmaceutical interventions (NPIs) to mitigate the spread of COVID-19. Design of efficient NPIs requires identification of the structure of the disease transmission network. We here identify the key…

Populations and Evolution · Quantitative Biology 2021-05-18 Simon Syga , Diana David-Rus , Yannik Schälte , Michael Meyer-Hermann , Haralampos Hatzikirou , Andreas Deutsch

Epidemiological models can not only be used to forecast the course of a pandemic like COVID-19, but also to propose and design non-pharmaceutical interventions such as school and work closing. In general, the design of optimal policies…

Optimization and Control · Mathematics 2023-04-06 Jan-Hendrik Niemann , Samuel Uram , Sarah Wolf , Nataša Djurdjevac Conrad , Martin Weiser

Most epidemic models are spatially aggregate and the index which is most used for planning and policy numbers, the r number, typically refers to a single system of interest. Even if r numbers are calculated for each of adjacent areas,…

Physics and Society · Physics 2020-05-18 Alan Wilson