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Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but they impose considerable societal, individual, and economic costs. We developed a general optimization framework to…

Populations and Evolution · Quantitative Biology 2025-12-15 Laura Müller , Fabio Sartori , Jonas Dehning , Maximilian F. Eggl , Viola Priesemann

Objectives. Public health officials need tools to assist with anticipating the healthcare resources required to confront the SARS-COV-2 pandemic. We built a modeling tool to aid practicing public health officials with estimating healthcare…

Populations and Evolution · Quantitative Biology 2020-05-14 Gabriel Rainisch , Eduardo A. Undurraga , Gerardo Chowell

Motivated by chemical reaction rules, we introduce a rule-based epidemiological framework for the systematic mathematical modelling of future pandemics. Here we stress that we do not have a specific model in mind, but a whole collection of…

Populations and Evolution · Quantitative Biology 2024-05-24 David Alonso , Steffen Bauer , Markus Kirkilionis , Lisa Maria Kreusser , Luca Sbano

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

We propose a mathematical framework, based on conic geometric programming, to control a susceptible-infected-susceptible viral spreading process taking place in a directed contact network with unknown contact rates. We assume that we have…

Optimization and Control · Mathematics 2014-12-09 Shuo Han , Victor M. Preciado , Cameron Nowzari , George J. Pappas

This paper introduces a non-parametric estimation algorithm designed to effectively estimate the joint distribution of model parameters with application to population pharmacokinetics. Our research group has previously developed the…

Currently there are many attempts around the world to use computers, smartphones, tablets and other electronic devices in order to stop the spread of COVID-19. Most of these attempts focus on collecting information about infected people, in…

Social and Information Networks · Computer Science 2020-04-07 Alexandru Popa

Various measures have been taken in different countries to mitigate the Covid-19 epidemic. But, throughout the world, many citizens don't understand well how these measures are taken and even question the decisions taken by their…

General Economics · Economics 2021-04-14 Samson Lasaulce , Chao Zhang , Vineeth Varma , Irinel Constantin Morarescu

Decision making in the face of a disaster requires the consideration of several complex factors. In such cases, Bayesian multi-criteria decision analysis provides a framework for decision making. In this paper, we present how to construct a…

Applications · Statistics 2021-12-21 Peter Strong , Aditi Shenvi , Xuewen Yu , K. Nadia Papamichail , Henry P Wynn , Jim Q Smith

The COVID-19 pandemic has influenced virtually all aspects of our lives. Across the world, countries have applied various mitigation strategies, based on social, political, and technological instruments. We postulate that multi-agent…

Computers and Society · Computer Science 2023-10-27 Wojciech Jamroga

Since roughly a decade ago, network science has focused among others on the problem of how the spreading of diseases depends on structural patterns. Here, we contribute to further advance our understanding of epidemic spreading processes by…

Computational Physics · Physics 2012-06-11 Sergio Gomez , Jesus Gomez-Gardenes , Yamir Moreno , Alex Arenas

The challenges posed by epidemics and pandemics are immense, especially if the causes are novel. This article introduces a versatile open-source simulation framework designed to model intricate dynamics of infectious diseases across diverse…

Multiagent Systems · Computer Science 2023-11-17 Zenin Easa Panthakkalakath , Neeraj , Jimson Mathew

Policy responses to COVID-19, particularly those related to non-pharmaceutical interventions, are unprecedented in scale and scope. Epidemiologists are more involved in policy decisions and evidence generation than ever before. However,…

Methodology · Statistics 2021-04-20 Noah A Haber , Emma Clarke-Deelder , Joshua A Salomon , Avi Feller , Elizabeth A Stuart

Social distancing and lockdown are the two main non-pharmaceutical interventions being used by the UK government to contain and control the COVID-19 epidemic; these are being applied uniformly across the entire country, even though the…

Populations and Evolution · Quantitative Biology 2020-04-28 L C G Rogers

Metapopulation epidemic models help capture the spatial dimension of infectious disease spread by dividing heterogeneous populations into separate but interconnected communities, represented by nodes in a network. In the event of an…

Populations and Evolution · Quantitative Biology 2025-02-21 Henrik Zunker , Philipp Dönges , Patrick Lenz , Seba Contreras , Martin J. Kühn

The recent COVID-19 pandemic highlighted the need of non-pharmaceutical interventions in the first stages of a pandemic. Among these, lockdown policies proved unavoidable yet extremely costly from an economic perspective. To better…

Optimization and Control · Mathematics 2021-12-14 Leonardo Cianfanelli , Francesca Parise , Daron Acemoglu , Giacomo Como , Asuman Ozdaglar

This paper concerns models and convergence principles for dealing with stochasticity in a wide range of algorithms arising in nonlinear analysis and optimization in Hilbert spaces. It proposes a flexible geometric framework within which…

Optimization and Control · Mathematics 2026-02-17 Patrick L. Combettes , Javier I. Madariaga

A novel coronavirus disease has emerged (later named COVID-19) and caused the world to enter a new reality, with many direct and indirect factors influencing it. Some are human-controllable (e.g. interventional policies, mobility and the…

Machine Learning · Computer Science 2021-01-12 Haonan Wu , Rajarshi Banerjee , Indhumathi Venkatachalam , Daniel Percy-Hughes , Praveen Chougale

A significant proportion of the infections driving the current {SARS-CoV-2} pandemic are transmitted asymptomatically. Here we introduce and study a simple epidemic model with separate compartments comprising asymptomatic and symptomatic…

Populations and Evolution · Quantitative Biology 2022-10-12 Maurice Görtz , Joachim Krug

As we reach the apex of the COVID-19 pandemic, the most pressing question facing us is: can we even partially reopen the economy without risking a second wave? We first need to understand if shutting down the economy helped. And if it did,…

Econometrics · Economics 2020-05-12 Anish Agarwal , Abdullah Alomar , Arnab Sarker , Devavrat Shah , Dennis Shen , Cindy Yang