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Background: Single-cell RNA sequencing (scRNA-seq) enables gene expression profiling at cellular resolution but is inherently affected by sparsity caused by dropout events, where expressed genes are recorded as zeros due to technical…

Genomics · Quantitative Biology 2026-04-15 Yuichiro Iwashita , Ahtisham Fazeel Abbasi , Koichi Kise , Andreas Dengel , Muhammad Nabeel Asim

In this study, we introduce a multi-modal approach that efficiently integrates multi-scale clinical and dermoscopy features within a single network, thereby substantially reducing model parameters. The proposed method includes three novel…

Image and Video Processing · Electrical Eng. & Systems 2024-03-31 Peng Tang , Tobias Lasser

Spatial transcriptomics has the potential to transform our understanding of RNA expression in tissues. Classical array-based technologies produce multiple-cell-scale measurements requiring deconvolution to recover single cell information.…

Recent approaches to point tracking are able to recover the trajectory of any scene point through a large portion of a video despite the presence of occlusions. They are, however, too slow in practice to track every point observed in a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Guillaume Le Moing , Jean Ponce , Cordelia Schmid

Deep learning-based medical image segmentation is increasingly used to support clinical diagnosis and develop new treatment strategies. However, model performance remains limited by the scarcity of high-quality annotated data and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Nathan Molinier , Hendrik Möller , Thomas Dagonneau , Anna Curto-Vilalta , Robert Graf , Matan Atad , Daniel Rueckert , Jan S. Kirschke , Julien Cohen-Adad

In this work, we are concerned with the diffusive optical tomography (DOT) problem in the case when only one or two pairs of Cauchy data is available. We propose a simple and efficient direct sampling method (DSM) to locate inhomogeneities…

Mathematical Physics · Physics 2014-10-07 Yat Tin Chow , Kazufumi Ito , Keji Liu , Jun Zou

Causal abstraction offers a principled framework for mechanistic interpretability, aligning a high-level causal model with the low-level computation realized by a neural network through counterfactual intervention analysis. Existing methods…

Machine Learning · Computer Science 2026-05-11 Jonathn Chang , Arya Datla , Ziv Goldfeld

Various imaging techniques have significantly enhanced our ability to visualize objects embedded within complex media such as biological tissues, fog, atmosphere, or various turbid media. Optical imaging, in particular, offers multiple…

Optics · Physics 2025-05-05 Mingwei He , Sujit K. Sahoo , Chengyuan Xiao , Cuong Dang

One-shot object detection aims at detecting novel objects according to merely one given instance. With extreme data scarcity, current approaches explore various feature fusions to obtain directly transferable meta-knowledge. Yet, their…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yizhou Zhao , Xun Guo , Yan Lu

Spatial transcriptomics (ST) provides high-resolution pathological images and whole-transcriptomic expression profiles at individual spots across whole-slide scales. This setting makes it an ideal data source to develop multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-11-27 Yuxiang Lin , Ling Luo , Ying Chen , Xushi Zhang , Zihui Wang , Wenxian Yang , Mengsha Tong , Rongshan Yu

Device-free (DF) localization in WLANs has been introduced as a value-added service that allows tracking indoor entities that do not carry any devices. Previous work in DF WLAN localization focused on the tracking of a single entity due to…

Networking and Internet Architecture · Computer Science 2012-07-19 Ibrahim Sabek , Moustafa Youssef

Multi-object tracking (MOT) is a fundamental task in computer vision that requires continuously tracking multiple targets while maintaining consistent identities across frames. However, most existing approaches primarily rely on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanchao Wang , Dawei Zhang , Chengzhuan Yang , Wei Liu , Minglu Li , Hua Wang , Zhonglong Zheng , Ming-Hsuan Yang

Spatial Transcriptomics (ST) provides spatially resolved gene expression profiles within intact tissue architecture, enabling molecular analysis in histological context. However, the high cost, limited throughput, and restricted data…

Machine Learning · Computer Science 2026-03-31 Yaoyu Fang , Jiahe Qian , Xinkun Wang , Lee A. Cooper , Bo Zhou

A neural-network (NN)-based method for high-speed, high-definition dynamic optical coherence tomography (DOCT) using full-field swept-source optical coherence microscopy (FF-SS-OCM) is demonstrated. FF-SS-OCM provides high-definition OCT…

Spacecraft Pose Estimation (SPE) is a fundamental capability for autonomous space operations such as rendezvous, docking, and in-orbit servicing. Hybrid pipelines that combine object detection, keypoint regression, and Perspective-n-Point…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Inder Pal Singh , Nidhal Eddine Chenni , Abd El Rahman Shabayek , Arunkumar Rathinam , Djamila Aouada

Deep convolutional neural networks have significantly boosted the performance of fundus image segmentation when test datasets have the same distribution as the training datasets. However, in clinical practice, medical images often exhibit…

Computer Vision and Pattern Recognition · Computer Science 2020-10-14 Shujun Wang , Lequan Yu , Kang Li , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

While single-cell RNA sequencing provides an understanding of the transcriptome of individual cells, its high sparsity, often termed dropout, hampers the capture of significant cell-cell relationships. Here, we propose scFP (single-cell…

Computational Engineering, Finance, and Science · Computer Science 2023-07-24 Sukwon Yun , Junseok Lee , Chanyoung Park

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

We address the computational and theoretical limitations of current distributional alignment methods for source-free unsupervised domain adaptation (SFUDA) using source class-mean features. In particular, we focus on estimating…

Machine Learning · Computer Science 2026-04-30 Yiming Zhang , Sitong Liu , Alex Cloninger

Single-cell RNA sequencing (scRNA-seq) has emerged as a transformative technology, offering unparalleled insights into the intricate landscape of cellular diversity and gene expression dynamics. The analysis of scRNA-seq data poses…

Molecular Networks · Quantitative Biology 2023-12-19 Hongsong Feng , Sean Cottrell , Yuta Hozumi , Guo-Wei Wei
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