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Ultrasound computed tomography (UCT) via full waveform inversion (FWI) enables high-resolution quantitative imaging for tissue characterization and disease diagnosis. However, UCT suffers from large computational burden and severe…
A closed-form analytical expression is derived for the limiting empirical squared singular value density of a spreading (signature) matrix corresponding to sparse low-density code-domain (LDCD) non-orthogonal multiple-access (NOMA) with…
Advances in single-cell sequencing have enabled high-resolution profiling of diverse molecular modalities, while integrating unpaired multi-omics single-cell data remains challenging. Existing approaches either rely on pair information or…
Spatial Transcriptomics (ST) is a technology that measures gene expression profiles within tissue sections while retaining spatial context. It reveals localized gene expression patterns and tissue heterogeneity, both of which are essential…
In this paper, we present a novel unsupervised domain adaptation (UDA) method, named Domain Adaptive Relational Reasoning (DARR), to generalize 3D multi-organ segmentation models to medical data collected from different scanners and/or…
Multivariate time series (MTS) data, when sampled irregularly and asynchronously, often present extensive missing values. Conventional methodologies for MTS analysis tend to rely on temporal embeddings based on timestamps that necessitate…
This study introduces SEFI (SEgmentation-Free Integration), a novel method for integrating morphological features of cell nuclei with spatial transcriptomics data. Cell segmentation poses a significant challenge in the analysis of spatial…
Deep sequencing has become one of the most popular tools for transcriptome profiling in biomedical studies. While an abundance of computational methods exists for "normalizing" sequencing data to remove unwanted between-sample variations…
Semantic Image Segmentation facilitates a multitude of real-world applications ranging from autonomous driving over industrial process supervision to vision aids for human beings. These models are usually trained in a supervised fashion…
The spatial location of cells within tissues and organs is crucial for the manifestation of their specific functions.Spatial transcriptomics technology enables comprehensive measurement of the gene expression patterns in tissues while…
Unsupervised Domain Adaptation (UDA) can effectively address domain gap issues in real-world image Super-Resolution (SR) by accessing both the source and target data. Considering privacy policies or transmission restrictions of source data…
In this paper, based on the spatio-temporal correlation of sensor nodes in the Internet of Things (IoT), a Spatio-temporal Scope information model (SSIM) is proposed to quantify the scope valuable information of sensor data, which decays…
As a powerful tool for characterizing cellular subpopulations and cellular heterogeneity, single cell RNA sequencing (scRNA-seq) technology offers advantages of high throughput and multidimensional analysis. However, the process of data…
This paper introduces a novel multi-object tracking (MOT) method, dubbed GenTrack, whose main contributions include: a hybrid tracking approach employing both stochastic and deterministic manners to robustly handle unknown and time-varying…
Searching for novel molecular compounds with desired properties is an important problem in drug discovery. Many existing frameworks generate molecules one atom at a time. We instead propose a flexible editing paradigm that generates…
DONNs leverage light propagation for efficient analog AI and signal processing. Advances in nanophotonic fabrication and metasurface-based wavefront engineering have opened new pathways to realize high-capacity DONNs across various spectral…
Single-cell RNA-sequencing (scRNA-seq) has become a routinely used technique to quantify the gene expression profile of thousands of single cells simultaneously. Analysis of scRNA-seq data plays an important role in the study of cell states…
Optical coherence tomography (OCT) imaging from different camera devices causes challenging domain shifts and can cause a severe drop in accuracy for machine learning models. In this work, we introduce a minimal noise adaptation method…
Motivation: Quality control of genomic data is an essential but complicated multi-step procedure, often requiring separate installation and expert familiarity with a combination of disparate bioinformatics tools. Results: To provide an…
RNA inverse folding, designing sequences to form specific 3D structures, is critical for therapeutics, gene regulation, and synthetic biology. Current methods, focused on sequence recovery, struggle to address structural objectives like…