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Adversarial-example-based fingerprinting approaches, which leverage the decision boundary characteristics of deep neural networks (DNNs) to craft fingerprints, have proven effective for model ownership protection. However, a fundamental…

Cryptography and Security · Computer Science 2026-03-24 Guang Yang , Ziye Geng , Yihang Chen , Changqing Luo

Atomic force microscopy (AFM or SPM) imaging is one of the best matches with machine learning (ML) analysis among microscopy techniques. The digital format of AFM images allows for direct utilization in ML algorithms without the need for…

Biological Physics · Physics 2025-01-07 Igor Sokolov

Current research on soft-biometrics showed that privacy-sensitive information can be deduced from biometric templates of an individual. Since for many applications, these templates are expected to be used for recognition purposes only, this…

Computer Vision and Pattern Recognition · Computer Science 2020-02-24 Philipp Terhörst , Marco Huber , Naser Damer , Florian Kirchbuchner , Arjan Kuijper

We introduce a convolutional neural network that operates directly on graphs. These networks allow end-to-end learning of prediction pipelines whose inputs are graphs of arbitrary size and shape. The architecture we present generalizes…

Molecular dynamic simulations are important in computational physics, chemistry, material, and biology. Machine learning-based methods have shown strong abilities in predicting molecular energy and properties and are much faster than DFT…

Molecular Networks · Quantitative Biology 2023-02-03 Zheng Yuan , Yaoyun Zhang , Chuanqi Tan , Wei Wang , Fei Huang , Songfang Huang

Accurate prediction of molecular properties is essential in drug discovery and related fields. However, existing graph neural networks (GNNs) often struggle to simultaneously capture both local and global molecular structures. In this work,…

Machine Learning · Computer Science 2025-08-26 XiaYu Liu , Chao Fan , Yang Liu , Hou-biao Li

Molecular assembly offers a promising path to detect life beyond Earth, while minimizing assumptions based on terrestrial life. As mass spectrometers will be central to upcoming Solar System missions, predicting molecular assembly from…

Machine Learning · Computer Science 2025-07-28 Lindsay A. Rutter , Abhishek Sharma , Ian Seet , David Obeh Alobo , An Goto , Leroy Cronin

Classical empirical force fields have dominated biomolecular simulation for over 50 years. Although widely used in drug discovery, crystal structure prediction, and biomolecular dynamics, they generally lack the accuracy and transferability…

Classical fingerprinting associates with each string a shorter string (its fingerprint), such that, with high probability, any two distinct strings can be distinguished by comparing their fingerprints alone. The fingerprints can be…

Quantum Physics · Physics 2009-11-07 Harry Buhrman , Richard Cleve , John Watrous , Ronald de Wolf

Automatic extraction of chemical structures from scientific literature plays a crucial role in accelerating research across fields ranging from drug discovery to materials science. Patent documents, in particular, contain molecular…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Lucas Morin , Gerhard Ingmar Meijer , Valéry Weber , Luc Van Gool , Peter W. J. Staar

Molecule property prediction is a fundamental problem for computer-aided drug discovery and materials science. Quantum-chemical simulations such as density functional theory (DFT) have been widely used for calculating the molecule…

Machine Learning · Computer Science 2019-11-26 Hiroyuki Shindo , Yuji Matsumoto

Understanding protein dynamics are essential for deciphering protein functional mechanisms and developing molecular therapies. However, the complex high-dimensional dynamics and interatomic interactions of biological processes pose…

Quantitative Methods · Quantitative Biology 2025-05-15 Tiexin Qin , Mengxu Zhu , Chunyang Li , Terry Lyons , Hong Yan , Haoliang Li

We describe two different modes for electronically detecting an adsorbed molecule using a nanoscale transistor. The attachment of an ionic molecular target shifts the threshold voltage through modulation of the depletion layer…

Mesoscale and Nanoscale Physics · Physics 2008-08-19 S. Vasudevan , K. Walczak , N. Kapur , M. Neurock , A. W. Ghosh

Molecular property prediction (MPP) is a crucial task in the drug discovery pipeline, which has recently gained considerable attention thanks to advances in deep neural networks. However, recent research has revealed that deep models…

Machine Learning · Computer Science 2023-07-03 Jun Xia , Lecheng Zhang , Xiao Zhu , Stan Z. Li

Atomic force microscopy (AFM) is an essential nanoinstrument technique for several applications such as cell biology and nanoelectronics metrology and inspection. The need for statistically significant sample sizes means that data…

Instrumentation and Detectors · Physics 2017-04-05 H. Sadeghian , R. Herfst , B. Dekker , J. Winters , T. Bijnagte , R. Rijnbeek

Large language models have revolutionized artificial intelligence by enabling large, generalizable models trained through self-supervision. This paradigm has inspired the development of scientific foundation models (FMs). However, applying…

Anonymity is a fundamental cryptographic primitive that hides the identities of both senders and receivers during message transmission over a network. Classical protocols cannot provide information-theoretic security for such task, and…

Quantum Physics · Physics 2025-12-25 Srijani Das , Manasi Patra , Tuhin Paul , Anish Majumdar , Ramij Rahaman

We discuss a novel approach to quantum information processing with molecules based on molecular degrees of freedom which are isolated from the environment as well as from the rest of the molecule. Such a degree of freedom can provide…

Atomic Physics · Physics 2023-11-27 Martin Zeppenfeld

In this study, we present a novel computational method for generating molecular fingerprints using multiparameter persistent homology (MPPH). This technique holds considerable significance for drug discovery and materials science, where…

Machine Learning · Computer Science 2023-12-14 Andac Demir , Francis Prael , Bulent Kiziltan

Property prediction on molecular graphs is an important application of Graph Neural Networks. Recently, unlabeled molecular data has become abundant, which facilitates the rapid development of self-supervised learning for GNNs in the…

Machine Learning · Computer Science 2023-10-31 Kha-Dinh Luong , Ambuj Singh